(Q34641933)

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Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection

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scholarly article

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Europe PubMed Central

3 August 2017

Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection (English)

1 reference

Europe PubMed Central

3 August 2017

Simian immunodeficiency virus

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12

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Europe PubMed Central

3 August 2017

21

object named as

Anthony S Fauci

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Europe PubMed Central

3 August 2017

object named as

Joseph Hiatt

6

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Nagadenahalli Byrareddy Siddappa

1

object named as

Siddappa N Byrareddy

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Europe PubMed Central

3 August 2017

Aftab A. Ansari

22

object named as

Aftab A Ansari

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Europe PubMed Central

3 August 2017

4

object named as

Claudia Cicala

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Europe PubMed Central

3 August 2017

Francois Villinger

20

object named as

Francois Villinger

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Europe PubMed Central

3 August 2017

3

object named as

James Arthos

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Europe PubMed Central

3 August 2017

Markus Brameier

11

object named as

Markus Brameier

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Europe PubMed Central

3 August 2017

14

object named as

Ann E Mayne

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Europe PubMed Central

3 August 2017

author name string

Brianne Kallam

2

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Europe PubMed Central

3 August 2017

Fatima Nawaz

5

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Europe PubMed Central

3 August 2017

Ellen N Kersh

7

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Europe PubMed Central

3 August 2017

Janet M McNicholl

8

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Europe PubMed Central

3 August 2017

Debra Hanson

9

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Europe PubMed Central

3 August 2017

Keith A Reimann

10

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Europe PubMed Central

3 August 2017

Kenneth Rogers

13

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Europe PubMed Central

3 August 2017

Paul Dunbar

15

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Europe PubMed Central

3 August 2017

Tara Villinger

16

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Europe PubMed Central

3 August 2017

Dawn Little

17

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Europe PubMed Central

3 August 2017

Tristram G Parslow

18

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Europe PubMed Central

3 August 2017

Philip J Santangelo

19

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Europe PubMed Central

3 August 2017

language of work or name

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publication date

24 November 2014

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Europe PubMed Central

3 August 2017

Nature Medicine

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20

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12

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1397-1400

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Europe PubMed Central

3 August 2017

https://scigraph.springernature.com/pub.10.1038/nm.3715

0 references

Biological agents for moderately to severely active ulcerative colitis: a systematic review and network meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Vedolizumab for the treatment of IBD: a selective therapeutic approach targeting pathogenic a4b7 cells.

1 reference

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Vedolizumab as induction and maintenance therapy for Crohn's disease

1 reference

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7 July 2018

Vedolizumab as induction and maintenance therapy for ulcerative colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

The frequency of α₄β₇(high) memory CD4⁺ T cells correlates with susceptibility to rectal simian immunodeficiency virus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Susceptibility to repeated, low-dose, rectal SHIVSF162P3 challenge is independent of TRIM5 genotype in rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

In captive rhesus macaques, cervicovaginal inflammation is common but not associated with the stable polymicrobial microbiome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Monoclonal antibodies to the V2 domain of MN-rgp120: fine mapping of epitopes and inhibition of α4β7 binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Animal models for microbicide studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques

1 reference

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7 July 2018

Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques

1 reference

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7 July 2018

The genotype of early-transmitting HIV gp120s promotes α (4) β(7)-reactivity, revealing α (4) β(7) +/CD4+ T cells as key targets in mucosal transmission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Blocking of α4β7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Resistance to Simian HIV infection is associated with high plasma interleukin-8, RANTES and Eotaxin in a macaque model of repeated virus challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

TRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus Monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Identification of novel MHC class I sequences in pig-tailed macaques by amplicon pyrosequencing and full-length cDNA cloning and sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Preliminary in vivo efficacy studies of a recombinant rhesus anti-alpha(4)beta(7) monoclonal antibody.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Assessing vaccine effects in repeated low-dose challenge experiments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

The mucosal barrier and immune activation in HIV pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Preclinical assessment of HIV vaccines and microbicides by repeated low-dose virus challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4257865

7 July 2018

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

1 reference

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7 July 2018

Identification of homing receptors that mediate the recruitment of CD4 T cells to the genital tract following intravaginal infection with Chlamydia trachomatis

1 reference

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7 July 2018

Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes

1 reference

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7 July 2018

Distinct roles of L-selectin and integrins alpha 4 beta 7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: the multistep model confirmed and refined

1 reference

https://api.crossref.org/works/10.1038%2FNM.3715

21 January 2018

Characterization and allelic polymorphisms of rhesus macaque (Macaca mulatta) IgG Fc receptor genes.

1 reference

https://api.crossref.org/works/10.1038%2FNM.3715

21 January 2018

Direct stringency comparison of two macaque models (single-high vs. repeat-low) for mucosal HIV transmission using an identical anti-HIV chemoprophylaxis intervention

1 reference

https://api.crossref.org/works/10.1038%2FNM.3715

21 January 2018

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10.1038/NM.3715

1 reference

Europe PubMed Central

3 August 2017

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1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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