(Q34654684)

English

Sirolimus-FKBP12.6 impairs endothelial barrier function through protein kinase C-α activation and disruption of the p120-vascular endothelial cadherin interaction

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Sirolimus-FKBP12.6 impairs endothelial barrier function through protein kinase C-α activation and disruption of the p120-vascular endothelial cadherin interaction (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

0 references

Frank D Kolodgie

7

object named as

Frank D Kolodgie

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

8

object named as

Aloke V Finn

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Anwer Habib

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Vinit Karmali

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Rohini Polavarapu

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Hirokuni Akahori

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Qi Cheng

5

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Kim Pachura

6

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

0 references

publication date

25 July 2013

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Arteriosclerosis, Thrombosis, and Vascular Biology

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

33

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

2425-2431

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Metformin impairs vascular endothelial recovery after stent placement in the setting of locally eluted mammalian target of rapamycin inhibitors via S6 kinase-dependent inhibition of cell proliferation

1 reference

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7 July 2018

Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.

1 reference

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7 July 2018

Myosin light chain kinase signaling in endothelial barrier dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

PKCα activation of p120-catenin serine 879 phospho-switch disassembles VE-cadherin junctions and disrupts vascular integrity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

In-stent neoatherosclerosis: a final common pathway of late stent failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Withdrawal of proliferation signal inhibitors due to adverse events in the maintenance phase of heart transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

The pathology of neoatherosclerosis in human coronary implants bare-metal and drug-eluting stents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Activation of protein kinase C isoforms and its impact on diabetic complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Regulation of endothelial permeability via paracellular and transcellular transport pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Calcineurin inhibitor-sparing regimens in solid organ transplantation: focus on improving renal function and nephrotoxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Endothelial Akt signaling is rate-limiting for rapamycin inhibition of mouse mammary tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

FK506 binding protein 12/12.6 depletion increases endothelial nitric oxide synthase threonine 495 phosphorylation and blood pressure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Decreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase Akt

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Signaling mechanisms regulating endothelial permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Thrombin-induced phosphorylation of the regulatory light chain of myosin II in cultured bovine corneal endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Role of Akt signaling in vascular homeostasis and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Ca(2+) signalling and PKCalpha activate increased endothelial permeability by disassembly of VE-cadherin junctions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Simvastatin improves disturbed endothelial barrier function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Multiple pathways control protein kinase C phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

SDZ RAD, a new rapamycin derivative: pharmacological properties in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Increased endothelial albumin permeability mediated by protein kinase C activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Rapamycin (AY-22,989), a new antifungal antibiotic. III. In vitro and in vivo evaluation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

7 July 2018

Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

26 October 2018

Proliferation signal inhibitor-induced decrease of vascular endothelial cadherin expression and increase of endothelial permeability in vitro are prevented by an anti-oxidant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

26 October 2018

Tolerance profile of the proliferation signal inhibitors everolimus and sirolimus in heart transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

26 October 2018

VE-cadherin-p120 interaction is required for maintenance of endothelial barrier function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

26 October 2018

Graft-versus-host disease prevention by rapamycin: cellular mechanisms

1 reference

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26 October 2018

Calcium antagonists ameliorate ischemia-induced endothelial cell permeability by inhibiting protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

26 October 2018

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3827918

26 October 2018

Removal of FKBP12/12.6 from endothelial ryanodine receptors leads to an intracellular calcium leak and endothelial dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23887639

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective binding of FKBP12.6 by the cardiac ryanodine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/23887639

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/ATVBAHA.113.301659

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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