(Q34657210)

3 August 2017

1 reference

title

Regulation of human dihydrofolate reductase activity and expression (English)

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3 August 2017

Emine Ercikan Abali

1

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3 August 2017

Nancy E Skacel

series ordinal

2

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3 August 2017

Hilal Celikkaya

series ordinal

3

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3 August 2017

Yi-Ching Hsieh

series ordinal

4

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3 August 2017

publication date

1 January 2008

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3 August 2017

published in

Vitamins and Hormones

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3 August 2017

volume

79

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3 August 2017

page(s)

267-292

1 reference

Kinetics of tetrahydrobiopterin synthesis by rabbit brain dihydrofolate reductase

3 August 2017

cites work

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7 January 2021

Preliminary evidence for involvement of the folate gene polymorphism 19bp deletion-DHFR in occurrence of autism.

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7 January 2021

Chromosomal organization of the human dihydrofolate reductase genes: dispersion, selective amplification, and a novel form of polymorphism

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7 January 2021

Nucleotide sequence and nuclease hypersensitivity of the Chinese hamster dihydrofolate reductase gene promoter region

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7 January 2021

Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase

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7 January 2021

The intracellular content of dihydrofolate reductase: possibilities for control and implications for chemotherapy

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7 January 2021

A perspective on enzyme catalysis.

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7 January 2021

Increased Level of Dihydrofolic Reductase in Leucocytes of Patients Treated with Amethopterin

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7 January 2021

THE "INDUCTION" OF DIHYDROFOLIC REDUCTASE ACTIVITY IN LEUKOCYTES AND ERYTHROCYTES OF PATIENTS TREATED WITH AMETHOPTERIN

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7 January 2021

Growth/cell cycle regulation of Sp1 phosphorylation

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7 January 2021

Dismutation of dihydrofolate by dihydrofolate reductase

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7 January 2021

The 5'-untranslated RNA of the human dhfr minor transcript alters transcription pre-initiation complex assembly at the major (core) promoter

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7 January 2021

5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review

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7 January 2021

A structurally conserved water molecule in Rossmann dinucleotide-binding domains

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7 January 2021

Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding

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7 January 2021

NADP-dependent enzymes. I: Conserved stereochemistry of cofactor binding

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7 January 2021

NADP-dependent enzymes. II: Evolution of the mono- and dinucleotide binding domains

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7 January 2021

Endothelial dihydrofolate reductase: critical for nitric oxide bioavailability and role in angiotensin II uncoupling of endothelial nitric oxide synthase

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7 January 2021

Cooperation of E2F-p130 and Sp1-pRb complexes in repression of the Chinese hamster dhfr gene

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7 January 2021

Intronless human dihydrofolate reductase genes are derived from processed RNA molecules

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7 January 2021

Specific binding of human dihydrofolate reductase protein to dihydrofolate reductase messenger RNA in vitro

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7 January 2021

Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation

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7 January 2021

Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Histone deacetylase 1 can repress transcription by binding to Sp1.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Effect of codon 22 mutations on substrate and inhibitor binding for human dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Dihydrofolate reductase protein inhibits its own translation by binding to dihydrofolate reductase mRNA sequences within the coding region

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Sequences downstream of the transcription initiation site modulate the activity of the murine dihydrofolate reductase promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Activation of the murine dihydrofolate reductase promoter by E2F1. A requirement for CBP recruitment

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Molecular genetic analysis of the human dihydrofolate reductase gene: relation with plasma total homocysteine, serum and red blood cell folate levels.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Relating protein motion to catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Increase of dihydrofolate reductase activity in cultured mammalian cells after exposure to methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy?

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Common dihydrofolate reductase 19-base pair deletion allele: a novel risk factor for preterm delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

The nucleotide sequence of the cDNA coding for the human dihydrofolic acid reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Discrete human dihydrofolate reductase gene transcripts present in polysomal RNA map with their 5' ends several hundred nucleotides upstream of the main mRNA start site

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

A human dihydrofolate reductase pseudogene and its relationship to the multiple forms of specific messenger RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Human dihydrofolate reductase gene is located in chromosome 5 and is unlinked to the related pseudogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Assignment of human dihydrofolate reductase gene to band q23 of chromosome 5 and of related pseudogene psi HD1 to chromosome 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Multiple transcription start sites, DNase I-hypersensitive sites, and an opposite-strand exon in the 5' region of the CHO dhfr gene

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

miRNAs on the move: miRNA biogenesis and the RNAi machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

The Rb/E2F pathway and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Retinoblastoma protein associates with SP1 and activates the hamster dihydrofolate reductase promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

An intron is required for dihydrofolate reductase protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Kainate-like neurotoxicity of folates

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Amelioration of sodium valproate‐induced neural tube defects in mouse fetuses by maternal folic acid supplementation during gestation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Modulation of Sp1-dependent transcription by a cis-acting E2F element in dhfr promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

The 19-bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR) may decrease rather than increase risk for spina bifida in the Irish population

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Proximal and long-range alterations in chromatin structure surrounding the Chinese hamster dihydrofolate reductase promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Identification of a base pair substitution at the tetranucleotide tandem repeat locus DHFRP2 (AAAC)n in a worldwide survey.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

The SWI/SNF complex--chromatin and cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Chemical and biological evolution of nucleotide-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Transcriptional regulation of the dihydrofolate reductase/rep-3 locus

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Structure, dynamics, and catalytic function of dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

A human dihydrofolate reductase intronless pseudogene with an Alu repetitive sequence: multiple DNA insertions at a single chromosomal site

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Site-specific demethylation and normal chromatin structure of the human dihydrofolate reductase gene promoter after transfection into CHO cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Identification of two initiator elements in the bidirectional promoter of the human dihydrofolate reductase and mismatch repair protein 1 genes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Functional role for Tyr 31 in the catalytic cycle of chicken dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Identification of amino acids required for the functional up-regulation of human dihydrofolate reductase protein in response to antifolate Treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Transcriptional regulation of the dihydrofolate reductase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Identification of critical amino acid residues on human dihydrofolate reductase protein that mediate RNA recognition

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Characterization of a cis-acting regulatory element in the protein-coding region of human dihydrofolate reductase mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Kinetic investigation of the functional role of phenylalanine-31 of recombinant human dihydrofolate reductase.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Folic acid and the inhibition of brain L-glutamic decarboxylase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Variation and expression of dihydrofolate reductase (DHFR) in relation to spina bifida

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Genomic organization and expression of the human MSH3 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UK.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

A functional 19-base pair deletion polymorphism of dihydrofolate reductase (DHFR) and risk of breast cancer in multivitamin users

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Divergent regulation of dihydrofolate reductase between malaria parasite and human host

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

Translational regulation of the synthesis of dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900409-3

7 January 2021

10.1016/S0083-6729(08)00409-3

Identifiers

DOI

1 reference

3 August 2017

1 reference