(Q34660829)

3 August 2017

1 reference

title

Epigenetic cancer therapies: DNA methyltransferase inhibitors (English)

1 reference

3 August 2017

Gordon Strathdee

1

0 references

author name string

Robert Brown

series ordinal

2

1 reference

PubMed ID

12036419

3 August 2017

language of work or name

English

0 references

publication date

1 June 2002

1 reference

Expert Opinion on Investigational Drugs

3 August 2017

1 reference

3 August 2017

11

1 reference

3 August 2017

6

1 reference

3 August 2017

747-754

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

3 August 2017

1 reference

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Limited up-regulation of DNA methyltransferase in human colon cancer reflecting increased cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Effects of DNA methylation on DNA-binding proteins and gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Methylation-induced repression--belts, braces, and chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

The "dark side" of chromatin remodeling: repressive effects on transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Pharmacological approach for optimization of the dose schedule of 5-Aza-2'-deoxycytidine (Decitabine) for the therapy of leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Genomic imprinting in mammals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

The DNA methylation machinery as a therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.6.747

10.1517/13543784.11.6.747

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

12036419