(Q34661764)

3 August 2017

title

Enantioselective synthesis of spliceostatin E and evaluation of biological activity (English)

1 reference

3 August 2017

1 reference

Arun K Ghosh

1

1 reference

3 August 2017

Anne M Veitschegger

2

1 reference

3 August 2017

Venkata Reddy Sheri

3

1 reference

3 August 2017

Kerstin A Effenberger

4

1 reference

3 August 2017

Beth E Prichard

5

1 reference

3 August 2017

Melissa S Jurica

6

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3 August 2017

language of work or name

English

0 references

publication date

25 November 2014

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3 August 2017

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3 August 2017

volume

16

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3 August 2017

issue

23

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3 August 2017

page(s)

6200-6203

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Enantioselective total syntheses of FR901464 and spliceostatin A and evaluation of splicing activity of key derivatives

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Coherence between cellular responses and in vitro splicing inhibition for the anti-tumor drug pladienolide B and its analogs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

An efficient, modular approach for the synthesis of (+)-strictifolione and a related natural product

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Cancer-Associated Perturbations in Alternative Pre-messenger RNA Splicing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Enantioselective syntheses of FR901464 and spliceostatin A: potent inhibitors of spliceosome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Phase I pharmacokinetic and pharmacodynamic study of the first-in-class spliceosome inhibitor E7107 in patients with advanced solid tumors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

The spliceosome as a target of novel antitumour drugs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Enantioselective total synthesis of (-)-zampanolide, a potent microtubule-stabilizing agent

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Spliceosome Structure and Function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

The spliceosome as target for anticancer treatment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Total syntheses, fragmentation studies, and antitumor/antiproliferative activities of FR901464 and its low picomolar analogue

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Application of olefin cross-metathesis to the synthesis of biologically active natural products

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Cytotoxic Spliceostatins from Burkholderia sp. and Their Semisynthetic Analogues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Splicing factor SF3b as a target of the antitumor natural product pladienolide.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Total synthesis of FR901464, an antitumor agent that regulates the transcription of oncogenes and tumor suppressor genes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

A general model for selectivity in olefin cross metathesis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

Total synthesis of microtubule-stabilizing agent (-)-laulimalide

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4260646

FR901464: total synthesis, proof of structure, and evaluation of synthetic analogues

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25423085

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Synthesis of a C4-epi-C1-C6 fragment of FR901464 using a novel bromolactolization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25423085

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25423085

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/OL503127R

1 reference

3 August 2017

1 reference

3 August 2017

1 reference