(Q34663655)

3 August 2017

1 reference

title

Is it time to reassess the BDNF hypothesis of depression? (English)

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3 August 2017

Groves JO

1

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3 August 2017

language of work or name

English

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publication date

14 August 2007

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3 August 2017

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3 August 2017

volume

12

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3 August 2017

issue

12

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3 August 2017

page(s)

1079-1088

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https://scigraph.springernature.com/pub.10.1038/sj.mp.4002075

3 August 2017

exact match

0 references

cites work

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Beyond the monoamine hypothesis: mechanisms, molecules and methods

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Neurobiology of depression

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7 January 2021

Neurotrophins and neuronal plasticity

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7 January 2021

Neurotrophin-evoked rapid excitation through TrkB receptors

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7 January 2021

Stress, Glucocorticoids, and Damage to the Nervous System: The Current State of Confusion.

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7 January 2021

The neurobiology of stress: from serendipity to clinical relevance

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7 January 2021

Depression: a case of neuronal life and death?

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Neurotrophic factors and regulation of mood: role of exercise, diet and metabolism

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https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Neurogenesis in the adult brain: death of a dogma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Hippocampal neurogenesis: regulation by stress and antidepressants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Neurotrophic factors: from structure-function studies to designing effective therapeutics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Neuroplasticity: from MRI to depressive symptoms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Apoptosis in the nervous system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Neurotrophins: roles in neuronal development and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Effects of electroconvulsive seizures and antidepressant drugs on brain-derived neurotrophic factor protein in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Effects of stress on neurotrophic factor expression in the rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Brain-derived neurotrophic factor mRNA downregulation produced by social isolation is blocked by intrahippocampal interleukin-1 receptor antagonist

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Acute social defeat reduces neurotrophin expression in brain cortical and subcortical areas in mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Postnatal repeated maternal deprivation produces age-dependent changes of brain-derived neurotrophic factor expression in selected rat brain regions.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Antidepressant-like effect of brain-derived neurotrophic factor (BDNF).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Bi-phasic change in BDNF gene expression following antidepressant drug treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Differential regulation of brain derived neurotrophic factor transcripts by antidepressant treatments in the adult rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Exercise, antidepressant treatment, and BDNF mRNA expression in the aging brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Chronic treatment with desipramine and fluoxetine modulate BDNF, CaMKKalpha and CaMKKbeta mRNA levels in the hippocampus of transgenic mice expressing antisense RNA against the glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Effects of chronic exercise and imipramine on mRNA for BDNF after olfactory bulbectomy in rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Anterograde transport of endogenous brain-derived neurotrophic factor in hippocampal mossy fibers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Gene profile of electroconvulsive seizures: induction of neurotrophic and angiogenic factors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Long-term repetitive transcranial magnetic stimulation increases the expression of brain-derived neurotrophic factor and cholecystokinin mRNA, but not neuropeptide tyrosine mRNA in specific areas of rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Chronic elevation of brain-derived neurotrophic factor by ampakines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

The neuroprotective agent memantine induces brain-derived neurotrophic factor and trkB receptor expression in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Decreased serum brain-derived neurotrophic factor levels in major depressed patients.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Low Brain-Derived Neurotrophic Factor (BDNF) levels in serum of depressed patients probably results from lowered platelet BDNF release unrelated to platelet reactivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: a preliminary study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Partial Normalization of Serum Brain-Derived Neurotrophic Factor in Remitted Patients after a Major Depressive Episode

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Effect of treatment on serum brain-derived neurotrophic factor levels in depressed patients.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Regulation of cAMP phosphodiesterase mRNAs expression in rat brain by acute and chronic fluoxetine treatment. An in situ hybridization study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Early social enrichment augments adult hippocampal BDNF levels and survival of BrdU-positive cells while increasing anxiety- and "depression"-like behavior

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Brain-derived neurotrophic factor in the ventral midbrain-nucleus accumbens pathway: a role in depression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

BDNF in anxiety and depression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Mice with reduced brain-derived neurotrophic factor expression show decreased choline acetyltransferase activity, but regular brain monoamine levels and unaltered emotional behavior

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Unusual behavioral phenotypes of inbred mouse strains.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Transgenic study of energy homeostasis equation: implications and confounding influences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Examination of behavioral deficits triggered by targeting Bdnf in fetal or postnatal brains of mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

The interrelationship of neuroticism, sex, and stressful life events in the prediction of episodes of major depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Forebrain-specific trkB-receptor knockout mice: behaviorally more hyperactive than "depressive".

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Recent advances in animal models of chronic antidepressant effects: the novelty-induced hypophagia test

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Transgenic brain-derived neurotrophic factor expression causes both anxiogenic and antidepressant effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Genetic epidemiology of major depression: review and meta-analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Major depressive disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Genome-wide linkage analysis of a composite index of neuroticism and mood-related scales in extreme selected sibships

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Linkage analysis of extremely discordant and concordant sibling pairs identifies quantitative-trait loci that influence variation in the human personality trait neuroticism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Genetic covariation between neuroticism and the symptoms of anxiety and depression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Neuroticism, major depression and gender: a population-based twin study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

A population-based twin study of the relationship between neuroticism and internalizing disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Heritability of the big five personality dimensions and their facets: a twin study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Further evidence against the environmental transmission of individual differences in neuroticism from a collaborative study of 45,850 twins and relatives on two continents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Genetic dissection of complex traits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Recent progress in psychiatric genetics-some hope but no hype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Neuroticism: a vulnerability marker for depression evidence from a family study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

The genetic basis of neuroticism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Association of a functional BDNF polymorphism and anxiety-related personality traits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Association study of a brain-derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behavior

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Association study of a brain‐derived neurotrophic‐factor genetic polymorphism and major depressive disorders, symptomatology, and antidepressant response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorder.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

No association between the BDNF Val66Met polymorphism and mood status in a non-clinical community sample of 7389 older adults.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

The Val66Met coding variant of the brain-derived neurotrophic factor (BDNF) gene does not contribute toward variation in the personality trait neuroticism.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Does measurement instrument moderate the association between the serotonin transporter gene and anxiety-related personality traits? A meta-analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

BDNF variation and mood disorders: a novel functional promoter polymorphism and Val66Met are associated with anxiety but have opposing effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

The Val66Met polymorphism of the brain-derived neurotrophic-factor gene is associated with geriatric depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Role of neurotrophic factors in depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

The mesolimbic dopamine reward circuit in depression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4002075

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4002075

1 reference

3 August 2017

1 reference