(Q46500200)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Carlos B. Duarte

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Bruno Manadas

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

João R Gomes

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

César S Mendes

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Mário Grãos

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

author name string

Melo CV

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Carvalho RF

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Carvalho AP

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

publication date

1 October 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

12 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

page(s)

1329-1343

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15905876%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401662

12 January 2020

exact match

0 references

cites work

Trk receptors: roles in neuronal signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

cAMP-induced switching in turning direction of nerve growth cones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Signal transduction underlying growth cone guidance by diffusible factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Brain-derived neurotrophic factor protects against ischemic cell damage in rat hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Post-occlusion treatment with BDNF reduces infarct size in a model of permanent occlusion of the middle cerebral artery in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Neuroprotection with noninvasive neurotrophin delivery to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Intravenous brain-derived neurotrophic factor reduces infarct size and counterregulates Bax and Bcl-2 expression after temporary focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Alterations in IGF-I, BDNF and NT-3 levels following experimental brain trauma and the effect of IGF-I administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Regional brain-derived neurotrophic factor mRNA and protein levels following transient forebrain ischemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Neurotrophins as synaptic modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Neurotrophins and their receptors: a convergence point for many signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

PI 3-kinase, Akt and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Structure, regulation and function of PKB/AKT--a major therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Mitochondrial dysfunction and glutamate excitotoxicity studied in primary neuronal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Activation of p42 mitogen-activated protein kinase in hippocampal long term potentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Insulin-stimulated protein kinase B phosphorylation on Ser-473 is independent of its activity and occurs through a staurosporine-insensitive kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Regulation of Akt/PKB activation by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Involvement of 3-phosphoinositide-dependent protein kinase-1 in the MEK/MAPK signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Regulation of c-Jun N-terminal kinase, p38 kinase and AP-1 DNA binding in cultured brain neurons: roles in glutamate excitotoxicity and lithium neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Expression of members of the trk family in the developing postnatal rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Pathogenesis of hippocampal neuronal death after hypoxia-ischemia changes during brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Neuronal cell death: a demise with different shapes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Down-regulation of the neurotrophin receptor TrkB following ligand binding. Evidence for an involvement of the proteasome and differential regulation of TrkA and TrkB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Neuroprotection by brain-derived neurotrophic factor is mediated by extracellular signal-regulated kinase and phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Activation of mitogen-activated protein kinase and p70S6 kinase is not correlated with cerebellar granule cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Apoptotic and antiapoptotic mechanisms in stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Brain ischemia and reperfusion: molecular mechanisms of neuronal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Cooperative expression of survival p-ERK and p-Akt signals in rat brain neurons after transient MCAO.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

The role of phosphatidylinositide-3-kinase in basal mitogen-activated protein kinase activity and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Platelet-derived-growth-factor stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle: role of pertussis-toxin-sensitive G-proteins, c-Src tyrosine kinases and phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Regulation of Raf-Akt Cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

A novel role for serum response factor in neuronal survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Brain-derived neurotrophic factor enhances neuronal translation by activating multiple initiation processes: comparison with the effects of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Small molecule peptidomimetic ligands of neurotrophin receptors, identifying binding sites, activation sites and regulatory sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Evidence for neuroprotective effects of endogenous brain-derived neurotrophic factor after global forebrain ischemia in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

K-252 compounds: modulators of neurotrophin signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Glutamate, but not dopamine, stimulates stress-activated protein kinase and AP-1-mediated transcription in striatal neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Mitochondria and the Bcl-2 family proteins in apoptosis signaling pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Cells Expressing mRNA for Neurotrophins and their Receptors During Embryonic Rat Development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Signal transduction events mediated by the BDNF receptor gp 145trkB in primary hippocampal pyramidal cell culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Potentiated necrosis of cultured cortical neurons by neurotrophins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Neurotrophins induce death of hippocampal neurons via the p75 receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

The anti-apoptotic protein ITA is essential for NGF-mediated survival of embryonic chick neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

The inhibitors of apoptosis (IAPs) and their emerging role in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Mitogen-activated protein kinase-independent pathways mediate the effects of nerve growth factor and cAMP on neuronal survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021

Role of desensitization of AMPA receptors on the neuronal viability and on the [Ca2+]ichanges in cultured rat hippocampal neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401662

7 January 2021