(Q40908497)

24 September 2017

title

The role of phosphatidylinositide-3-kinase in basal mitogen-activated protein kinase activity and cell survival (English)

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24 September 2017

H H Versteeg

1

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24 September 2017

M W Evertzen

series ordinal

2

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24 September 2017

S J van Deventer

series ordinal

3

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24 September 2017

M P Peppelenbosch

series ordinal

4

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24 September 2017

language of work or name

English

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publication date

1 January 2000

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24 September 2017

number of pages

5

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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24 September 2017

volume

465

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24 September 2017

issue

1

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24 September 2017

page(s)

69-73

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Phosphoinositide 3-kinases: a conserved family of signal transducers

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2899%2901701-9

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

21 January 2018

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

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A heterotrimeric GTPase-regulated isoform of PI3K and the regulation of its potential effectors

21 January 2018

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Requirement for phosphatidylinositol 3'-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin

21 January 2018

1 reference

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The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

21 January 2018

1 reference

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Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

21 January 2018

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Conditional inhibition of the mitogen-activated protein kinase cascade by wortmannin. Dependence on signal strength

21 January 2018

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Alpha1 adrenergic receptors activate phosphatidylinositol 3-kinase in human vascular smooth muscle cells. Role in mitogenesis

21 January 2018

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Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

21 January 2018

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

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Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

21 January 2018

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Ras promotes cell survival in Drosophila by downregulating hid expression

21 January 2018

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The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling

21 January 2018

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Comparison of in vitro anticancer-drug-screening data generated with a tetrazolium assay versus a protein assay against a diverse panel of human tumor cell lines

21 January 2018

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

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Phosphatidylinositol 3-OH kinase activity is not required for activation of mitogen-activated protein kinase by cytokines

21 January 2018

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

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Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

21 January 2018

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Disruption of epithelial cell-matrix interactions induces apoptosis

21 January 2018

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Control of adhesion-dependent cell survival by focal adhesion kinase

21 January 2018

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Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts

21 January 2018

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Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

21 January 2018

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Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion

21 January 2018

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Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

21 January 2018

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Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

21 January 2018

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Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

21 January 2018

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Two major signal pathways linked

21 January 2018

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Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)

21 January 2018

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10.1016/S0014-5793(99)01701-9

7 January 2021

Identifiers

DOI

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24 September 2017

1 reference