(Q34663915)

25218284

3 August 2017

title

Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells (English)

1 reference

3 August 2017

1

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1 June 2020

Talal A Chatila

13

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1 June 2020

12

Sevgi Keles

1 reference

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1 June 2020

author name string

Henner Morbach

2

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1 June 2020

Sumana Ullas

3

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1 June 2020

Jason M Bannock

4

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1 June 2020

Christopher Massad

5

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1 June 2020

Laurence Menard

6

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1 June 2020

Isil Barlan

7

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1 June 2020

Gerard Lefranc

8

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1 June 2020

Helen Su

9

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1 June 2020

Majed Dasouki

10

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1 June 2020

Waleed Al-Herz

11

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1 June 2020

Raif S Geha

14

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1 June 2020

Eric Meffre

15

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1 June 2020

language of work or name

English

0 references

publication date

11 September 2014

1 reference

25218284

3 August 2017

number of pages

10

1 reference

The Journal of Allergy and Clinical Immunology

inferred from page(s)

published in

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1 June 2020

volume

134

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1 June 2020

issue

6

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1 June 2020

page(s)

1365-1374

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Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation

1 June 2020

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7 July 2018

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7 July 2018

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DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

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Clinical, immunologic and genetic profiles of DOCK8-deficient patients in Kuwait

7 July 2018

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Additional diverse findings expand the clinical presentation of DOCK8 deficiency

7 July 2018

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The establishment of early B cell tolerance in humans: lessons from primary immunodeficiency diseases

7 July 2018

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The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

7 July 2018

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Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans

7 July 2018

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Dedicator of cytokinesis 8 (DOCK8) deficiency

7 July 2018

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Successful engraftment of donor marrow after allogeneic hematopoietic cell transplantation in autosomal-recessive hyper-IgE syndrome caused by dedicator of cytokinesis 8 deficiency.

7 July 2018

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Complement receptor 2/CD21- human naive B cells contain mostly autoreactive unresponsive clones

7 July 2018

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Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

7 July 2018

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Combined immunodeficiency associated with DOCK8 mutations

7 July 2018

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Defects along the T(H)17 differentiation pathway underlie genetically distinct forms of the hyper IgE syndrome

7 July 2018

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CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Clinical, immunological and molecular characterization of DOCK8 and DOCK8-like deficient patients: single center experience of twenty-five patients

26 October 2018

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Clinical and immunological correction of DOCK8 deficiency by allogeneic hematopoietic stem cell transplantation following a reduced toxicity conditioning regimen.

26 October 2018

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Expansion of functionally anergic CD21-/low marginal zone-like B cell clones in hepatitis C virus infection-related autoimmunity

26 October 2018

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Single-cell analysis of the human T regulatory population uncovers functional heterogeneity and instability within FOXP3+ cells.

26 October 2018

1 reference

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Successful long-term correction of autosomal recessive hyper-IgE syndrome due to DOCK8 deficiency by hematopoietic stem cell transplantation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261031

Different proliferative potential and migratory characteristics of human CD4+ regulatory T cells that express either CD45RA or CD45RO.

26 October 2018

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Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndromes.

26 October 2018

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Successful allogeneic hematopoietic stem cell transplantation for DOCK8 deficiency

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4261031

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

26 October 2018

1 reference

12 December 2020

Curative treatment of autosomal-recessive hyper-IgE syndrome by hematopoietic cell transplantation

1 reference

12 December 2020

Successful bone marrow transplantation for DOCK8 deficient hyper IgE syndrome

1 reference

12 December 2020

Treosulfan-based conditioning in DOCK8 deficiency: complete lympho-hematopoietic reconstitution with minimal toxicity

1 reference

12 December 2020

10.1016/J.JACI.2014.07.042

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25218284%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25218284%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

25218284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25218284%20AND%20SRC:MED&resulttype=core&format=json