(Q34666156)

English

FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas.

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas. (English)

1 reference

Europe PubMed Central

3 August 2017

pulmonary fibrosis

1 reference

based on heuristic

inferred from title

idiopathic pulmonary fibrosis

1 reference

based on heuristic

inferred from title

author name string

Richard Seonghun Nho

1

1 reference

Europe PubMed Central

3 August 2017

Mark Peterson

2

1 reference

Europe PubMed Central

3 August 2017

Polla Hergert

3

1 reference

Europe PubMed Central

3 August 2017

Craig A Henke

4

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

8 April 2013

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

8

1 reference

Europe PubMed Central

3 August 2017

4

1 reference

Europe PubMed Central

3 August 2017

e61017

1 reference

Europe PubMed Central

3 August 2017

copyright license

Creative Commons Attribution 4.0 International

8 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Calpain 2 regulates Akt-FoxO-p27(Kip1) protein signaling pathway in mammary carcinoma

1 reference

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7 July 2018

Pathological alteration of FoxO3a activity promotes idiopathic pulmonary fibrosis fibroblast proliferation on type i collagen matrix

1 reference

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7 July 2018

Increased cell surface Fas expression is necessary and sufficient to sensitize lung fibroblasts to Fas ligation-induced apoptosis: implications for fibroblast accumulation in idiopathic pulmonary fibrosis.

1 reference

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7 July 2018

The extracellular matrix: an active or passive player in fibrosis?

1 reference

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7 July 2018

Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis

1 reference

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7 July 2018

Unregulated miR-96 induces cell proliferation in human breast cancer by downregulating transcriptional factor FOXO3a

1 reference

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7 July 2018

Src and caveolin-1 reciprocally regulate metastasis via a common downstream signaling pathway in bladder cancer

1 reference

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7 July 2018

Pathologic caveolin-1 regulation of PTEN in idiopathic pulmonary fibrosis

1 reference

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7 July 2018

beta1-Integrin-collagen interaction suppresses FoxO3a by the coordination of Akt and PP2A

1 reference

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7 July 2018

TGF-beta-FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia

1 reference

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7 July 2018

Deletion of caveolin-1 protects hyperoxia-induced apoptosis via survivin-mediated pathways

1 reference

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7 July 2018

Deregulation of FOXO3A during prostate cancer progression

1 reference

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7 July 2018

Association of FOXO3A variation with human longevity confirmed in German centenarians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27(Kip1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Cytokine-mediated FOXO3a phosphorylation suppresses FasL expression in hemopoietic cell lines: investigations of the role of Fas in apoptosis due to cytokine starvation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Genomic and morphological changes of neuroblastoma cells in response to three-dimensional matrices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

New insights into the pathogenesis and treatment of idiopathic pulmonary fibrosis: a potential role for stem cells in the lung parenchyma and implications for therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

PTEN regulates fibroblast elimination during collagen matrix contraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Idiopathic pulmonary fibrosis : new concepts in pathogenesis and implications for drug therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Incidence and prevalence of idiopathic pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Targeting genes for treatment in idiopathic pulmonary fibrosis: challenges and opportunities, promises and pitfalls.

1 reference

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7 July 2018

FOXO factors: a matter of life and death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness

1 reference

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7 July 2018

FOXO transcription factors at the interface between longevity and tumor suppression

1 reference

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7 July 2018

Lack of telopeptides in fibrillar collagen I promotes the invasion of a metastatic breast tumor cell line

1 reference

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7 July 2018

Apoptosis as a therapeutic target for the treatment of lung disease

1 reference

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7 July 2018

Caveolin-1 in oncogenic transformation, cancer, and metastasis

1 reference

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7 July 2018

Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Direct control of caveolin-1 expression by FOXO transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

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Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Possible involvement of aminotelopeptide in self-assembly and thermal stability of collagen I as revealed by its removal with proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Myofibroblasts. I. Paracrine cells important in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Idiopathic pulmonary fibrosis: current concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

The roles of the myofibroblast in idiopathic pulmonary fibrosis. Ultrastructural and immunohistochemical features of sites of active extracellular matrix synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

Caveolin, a protein component of caveolae membrane coats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3620276

7 July 2018

The definition of fibrogenic processes in fibroblastic foci of idiopathic pulmonary fibrosis based on morphometric quantification of extracellular matrices.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061017

21 January 2018

Role of the Akt/FoxO3a pathway in TGF-beta1-mediated mesangial cell dysfunction: a novel mechanism related to diabetic kidney disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061017

21 January 2018

Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0061017

21 January 2018

Does the triple helical domain of type I collagen encode molecular recognition and fiber assembly while telopeptides serve as catalytic domains? Effect of proteolytic cleavage on fibrillogenesis and on collagen-collagen interaction in fibers

1 reference

https://pubmed.ncbi.nlm.nih.gov/23580232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assembly of type I collagen: fusion of fibril subunits and the influence of fibril diameter on mechanical properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/23580232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/23580232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0061017

1 reference

Europe PubMed Central

3 August 2017

2013PLoSO...861017N

0 references

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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