(Q36429676)

14 August 2017

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title

FOXO factors: a matter of life and death (English)

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14 August 2017

Haojie Huang

1

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14 August 2017

Donald J Tindall

series ordinal

2

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14 August 2017

language of work or name

English

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publication date

1 February 2006

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14 August 2017

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14 August 2017

volume

2

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14 August 2017

issue

1

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14 August 2017

page(s)

83-89

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Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

FoxO6, a novel member of the FoxO class of transcription factors with distinct shuttling dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Direct control of the Forkhead transcription factor AFX by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Negative regulation of the forkhead transcription factor FKHR by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Forkhead transcription factors contribute to execution of the mitotic programme in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1).

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Akt activation promotes degradation of tuberin and FOXO3a via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Androgens negatively regulate forkhead transcription factor FKHR (FOXO1) through a proteolytic mechanism in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Molecular pathogenesis of rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

PAX3-FKHR transformation increases 26 S proteasome-dependent degradation of p27Kip1, a potential role for elevated Skp2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Role of the F-box protein Skp2 in lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

Skp2 is oncogenic and overexpressed in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2F14796694.2.1.83

21 January 2018

Identifiers

DOI

10.2217/14796694.2.1.83

1 reference

release_4l5xqkxuunfk3n7mflzshdmhpe

14 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4l5xqkxuunfk3n7mflzshdmhpe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference