(Q42472986)

English

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

scientific article published on June 1999

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scholarly article

1 reference

Europe PubMed Central

1 November 2017

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence (English)

1 reference

Europe PubMed Central

1 November 2017

phosphorylation

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1 reference

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inferred from title

author name string

S Guo

1

1 reference

Europe PubMed Central

1 November 2017

G Rena

2

1 reference

Europe PubMed Central

1 November 2017

S Cichy

3

1 reference

Europe PubMed Central

1 November 2017

X He

4

1 reference

Europe PubMed Central

1 November 2017

P Cohen

5

1 reference

Europe PubMed Central

1 November 2017

T Unterman

6

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Europe PubMed Central

1 November 2017

language of work or name

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publication date

1 June 1999

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Europe PubMed Central

1 November 2017

number of pages

9

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Journal of Biological Chemistry

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Europe PubMed Central

1 November 2017

274

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Europe PubMed Central

1 November 2017

24

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Europe PubMed Central

1 November 2017

17184-17192

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Europe PubMed Central

1 November 2017

Common genetic variation in the promoter of the human apo CIII gene abolishes regulation by insulin and may contribute to hypertriglyceridemia

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A multicomponent insulin response sequence mediates a strong repression of mouse glucose-6-phosphatase gene transcription by insulin

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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Mechanism of activation and function of protein kinase B.

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Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Parallel signal processing among mammalian MAPKs

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Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216

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4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

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Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene.

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Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor

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daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

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Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

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Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)

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Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

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Cloning and characterization of the t(X;11) breakpoint from a leukemic cell line identify a new member of the forkhead gene family

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Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

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The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator

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Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase

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1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells

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Interleukin 3-dependent survival by the Akt protein kinase

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TOR signalling and control of cell growth

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Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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Direct control of the Forkhead transcription factor AFX by protein kinase B

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Identifiers

10.1074/JBC.274.24.17184

1 reference

Europe PubMed Central

1 November 2017

1 reference

Europe PubMed Central

1 November 2017

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