(Q34671934)

3 August 2017

title

Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB. (English)

1 reference

3 August 2017

1 reference

19

Bernhard Radlwimmer

0 references

Manuela Zucknick

8

Manuela Zucknick

0 references

Stephan Stilgenbauer

26

Stephan Stilgenbauer

0 references

Maïwen Caudron-Herger

Maïwen Caudron-Herger

9

0 references

Sudhir Thakurela

Sudhir Thakurela

15

0 references

Daniel Mertens

Daniel Mertens

27

0 references

Karsten Rippe

Karsten Rippe

22

0 references

Stefan Wiemann

Stefan Wiemann

21

0 references

Hartmut Döhner

24

Hartmut Döhner

1 reference

3 August 2017

25

Peter Lichter

1 reference

3 August 2017

Angela Garding

1

1 reference

3 August 2017

Nupur Bhattacharya

2

1 reference

3 August 2017

Rainer Claus

3

1 reference

3 August 2017

Melanie Ruppel

4

1 reference

3 August 2017

Cordula Tschuch

5

1 reference

3 August 2017

Katharina Filarsky

6

1 reference

3 August 2017

Irina Idler

7

1 reference

3 August 2017

Manuela Zucknick

8

1 reference

3 August 2017

Christopher Oakes

10

1 reference

3 August 2017

Verena Fleig

11

1 reference

3 August 2017

Ioanna Keklikoglou

12

1 reference

3 August 2017

Danilo Allegra

13

1 reference

3 August 2017

Leticia Serra

14

1 reference

3 August 2017

Vijay Tiwari

16

1 reference

3 August 2017

Dieter Weichenhan

17

1 reference

3 August 2017

Axel Benner

18

1 reference

3 August 2017

Hanswalter Zentgraf

20

1 reference

3 August 2017

Christoph Plass

23

1 reference

3 August 2017

publication date

4 April 2013

1 reference

3 August 2017

1 reference

3 August 2017

volume

9

1 reference

3 August 2017

issue

4

1 reference

3 August 2017

page(s)

e1003373

1 reference

Creative Commons Attribution 4.0 International

3 August 2017

copyright license

start time

4 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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TRIM13 regulates ER stress induced autophagy and clonogenic ability of the cells

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Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

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Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies.

7 July 2018

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Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

7 July 2018

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Coding RNAs with a non-coding function: maintenance of open chromatin structure

7 July 2018

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The prognostic significance of various 13q14 deletions in chronic lymphocytic leukemia.

7 July 2018

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Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia

7 July 2018

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7 July 2018

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The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia

7 July 2018

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7 July 2018

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Large non-coding RNAs: missing links in cancer?

7 July 2018

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MicroRNAs modulate the noncanonical transcription factor NF-kappaB pathway by regulating expression of the kinase IKKalpha during macrophage differentiation

7 July 2018

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Characterization of the RNA content of chromatin

7 July 2018

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All you need is a Mir-acle: the role of nontranslated RNAs in the suppression of B cell chronic lymphocytic leukemia

7 July 2018

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13q14 deletions in CLL involve cooperating tumor suppressors

7 July 2018

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The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia

7 July 2018

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The human retinoblastoma gene is imprinted

7 July 2018

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The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

7 July 2018

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From pathogenesis to treatment of chronic lymphocytic leukaemia

7 July 2018

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High-throughput detection of nuclear factor-kappaB activity using a sensitive oligo-based chemiluminescent enzyme-linked immunosorbent assay

7 July 2018

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Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia

7 July 2018

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Regulatory roles of natural antisense transcripts

7 July 2018

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DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

7 July 2018

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miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer

7 July 2018

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MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma

7 July 2018

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Chronic lymphocytic leukemia and 13q14: miRs and more

7 July 2018

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Evolution and functions of long noncoding RNAs

7 July 2018

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Long non-coding RNAs: insights into functions

7 July 2018

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A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster

7 July 2018

1 reference

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The antisense transcriptomes of human cells

7 July 2018

1 reference

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Differential role of the transcription factor NF-kappaB in selection and survival of CD4+ and CD8+ thymocytes

7 July 2018

1 reference

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The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

7 July 2018

1 reference

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miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes.

7 July 2018

1 reference

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Monoclonal B-cell lymphocytosis and chronic lymphocytic leukemia

7 July 2018

1 reference

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Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians

7 July 2018

1 reference

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Bone marrow fibroblasts induce expression of PI3K/NF-kappaB pathway genes and a pro-angiogenic phenotype in CLL cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Molecular allelokaryotyping of early-stage, untreated chronic lymphocytic leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer

7 July 2018

1 reference

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Smad7 sensitizes tumor necrosis factor induced apoptosis through the inhibition of antiapoptotic gene expression by suppressing activation of the nuclear factor-kappaB pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice

7 July 2018

1 reference

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Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD

7 July 2018

1 reference

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Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Temporal genetic program following B-cell receptor cross-linking: altered balance between proliferation and death in healthy and malignant B cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Genome-wide profiling of CpG methylation identifies novel targets of aberrant hypermethylation in myeloid leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Allelic silencing at the tumor-suppressor locus 13q14.3 suggests an epigenetic tumor-suppressor mechanism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Accurate quantification of DNA methylation using combined bisulfite restriction analysis coupled with the Agilent 2100 Bioanalyzer platform

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

The role of chromatin structure in regulating the expression of clustered genes.

7 July 2018

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Genetics of Paget's disease of bone.

7 July 2018

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Control of lymphocyte development by nuclear factor-kappaB.

7 July 2018

1 reference

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Chronic lymphocytic leukemia

7 July 2018

1 reference

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NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

DLEU2 encodes an antisense RNA for the putative bicistronic RFP2/LEU5 gene in humans and mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

7 July 2018

1 reference

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MicroRNAs: genomics, biogenesis, mechanism, and function

7 July 2018

2 references

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7 July 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003373

Involvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway.

21 January 2018

1 reference

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Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Capillary electrophoretic analysis of genomic DNA methylation levels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Methylation of histone H3 Lys 4 in coding regions of active genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Identification of novel genes coding for small expressed RNAs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

B-cell neoplasia associated gene with multiple splicing (BCMS): the candidate B-CLL gene on 13q14 comprises more than 560 kb covering all critical regions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

The tripartite motif family identifies cell compartments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Comparative sequence analysis of a region on human chromosome 13q14, frequently deleted in B-cell chronic lymphocytic leukemia, and its homologous region on mouse chromosome 14.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

CD40 ligand in CLL pathogenesis and therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Polymorphic imprinting of the serotonin-2A (5-HT2A) receptor gene in human adult brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

The overgrown hematopoietic organs-31 tumor suppressor gene of Drosophila encodes an Importin-like protein accumulating in the nucleus at the onset of mitosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003373

Quantification of DNA methylation in electrofluidics chips (Bio-COBRA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003373

Global, comparative analysis of tissue-specific promoter CpG methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003373

A gene expression map for the euchromatic genome of Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003373

The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003373

The novel nuclear factor-kappaB inhibitor LC-1 is equipotent in poor prognostic subsets of chronic lymphocytic leukemia and shows strong synergy with fludarabine

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003373

AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells: interference with the Akt/NF-kappaB survival pathway.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616974

Exclusion of Leu1 and Leu2 genes as tumor suppressor genes in 13q14.3-deleted B-CLL

26 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003373

Characterization of a novel B-CLL candidate gene--DLEU7--located in the 13q14 tumor suppressor locus

21 January 2018

1 reference

12 December 2020

Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma

1 reference

12 December 2020

Epigenetic regulation of the human retinoblastoma tumor suppressor gene promoter by CTCF

1 reference

12 December 2020

In-vivo quantification of primary microRNA processing by Drosha with a luciferase based system

1 reference

12 December 2020

Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival

1 reference

12 December 2020

Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines

1 reference

12 December 2020

Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector

1 reference

12 December 2020

The 13q and 11q B-cell chronic lymphocytic leukaemia-associated regions derive from a common ancestral region in the zebrafish

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1003373

Identifiers

DOI

1 reference

3 August 2017

1 reference

3 August 2017

1 reference