(Q34674654)

3 August 2017

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title

Pefloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. (English)

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3 August 2017

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Gonzalez JP

1

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PubMed ID

2663414

3 August 2017

Henwood JM

series ordinal

2

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3 August 2017

1 May 1989

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3 August 2017

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3 August 2017

37

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3 August 2017

628-668

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3 August 2017

5

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https://scigraph.springernature.com/pub.10.2165/00003495-198937050-00003

3 August 2017

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cites work

Interaction between the fluoroquinolones and the bronchodilator theophylline

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12 December 2020

Efficacy and safety of pefloxacin in the treatment of severe infections in patients hospitalized in intensive care units

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12 December 2020

Activity of the newer quinolones against Chlamydia trachomatis

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12 December 2020

In vitro activity of five new quinolones against cultivable mycobacteria

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12 December 2020

Pharmacokinetics of pefloxacin in normal and impaired renal function

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12 December 2020

Pefloxacin in the treatment of nosocomial lower respiratory tract infections in intensive care patients

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12 December 2020

Cross-resistance among cinoxacin, ciprofloxacin, DJ-6783, enoxacin, nalidixic acid, norfloxacin, and oxolinic acid after in vitro selection of resistant populations

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12 December 2020

Intraperitoneal penetration of pefloxacin

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12 December 2020

The adverse effects of fluoroquinolones

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12 December 2020

Quinolone/ureidopenicillin cross-resistance

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12 December 2020

Effects of subinhibitory concentrations of pefloxacin on the adherence of Staphylococcus aureus to human cells

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12 December 2020

[Treatment of septicemia and endocarditis with pefloxacine. 15 cases].

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12 December 2020

New synthetic quinolone antibacterial agents and serum concentration of theophylline

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12 December 2020

Steady-state kinetics of the quinolone derivatives ofloxacin, enoxacin, ciprofloxacin and pefloxacin during maintenance treatment with theophylline

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12 December 2020

Pefloxacin in the treatment of lower respiratory tract infections in geriatrics

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12 December 2020

Inhibition of DNA replication in vitro by pefloxacin

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12 December 2020

Ciprofloxacin and tenosynovitis

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12 December 2020

In-vitro activity of lomefloxacin in comparison with pefloxacin and ofloxacin

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12 December 2020

In vitro activity of four fluoroquinolones against eighty-six isolates of mycobacteria

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12 December 2020

In vitro activity of pefloxacin compared to that of quinolones and other antimicrobial agents

1 reference

12 December 2020

Steady-state levels of pefloxacin and its metabolites in patients with severe renal impairment

1 reference

12 December 2020

Comparative in vitro activity of amifloxacin and five other fluoroquinolone antimicrobial agents and preliminary criteria for the disk susceptibility test.

1 reference

12 December 2020

Activities of pefloxacin and ciprofloxacin in experimentally induced Pseudomonas pneumonia in neutropenic guinea pigs

1 reference

12 December 2020

Diffusion of ofloxacin into the cerebrospinal fluid in patients with bacterial meningitis

1 reference

12 December 2020

Antimicrobial chemotherapy of chlamydial infection: where next?

1 reference

12 December 2020

Efficacy and safety of pefloxacin in the treatment of patients with complicated urinary tract infections

1 reference

12 December 2020

Pefloxacin in acute exacerbations of chronic bronchitis

1 reference

12 December 2020

Mode of Incomplete Cross-Resistance Among Pipemidic, Piromidic, and Nalidixic Acids

1 reference

12 December 2020

Combination of a 3d-generation cephalosporin (cefotaxime or ceftazidime) and a new quinolone (pefloxacine) in the treatment of febrile episodes in neutropenic diseases (37 cases)

1 reference

12 December 2020

Prospective randomized comparative trial of pefloxacin versus cotrimoxazole in the treatment of typhoid fever in adults

1 reference

12 December 2020

Comparative in vitro effect of 7 quinolones on Ureaplasma urealyticum

1 reference

12 December 2020

In-vitro selection of bacteria resistant to the 4-quinolone agents.

1 reference

12 December 2020

Cross-resistance of nalidixic acid resistant Enterobacteriaceae to new quinolones and other antimicrobials.

1 reference

12 December 2020

Correlates of therapeutic efficacy in experimental methicillin-resistant Staphylococcus aureus endocarditis.

1 reference

12 December 2020

Comparative in-vitro activity of five fluoroquinolones against mycobacteria

1 reference

12 December 2020

A review on the impact of 4-quinolones on the normal oropharyngeal and intestinal human microflora

1 reference

12 December 2020

Comparative in vitro activities of ciprofloxacin, enoxacin, norfloxacin, ofloxacin and pefloxacin against Bacteroides fragilis and Clostridium difficile

1 reference

12 December 2020

In vitro effect of combinations of netilmicin and amikacin with fosfomycin and pefloxacin on 31 strains of heterogeneous methicillin- resistant Staphylococcus aureus

1 reference

12 December 2020

Oral ciprofloxacin in the treatment of elderly patients with complicated urinary tract infections due to trimethoprim/sulfamethoxazole-resistant bacteria.

1 reference

12 December 2020

In vitro susceptibility of Campylobacter jejuni to 27 antimicrobial agents and various combinations of beta-lactams with clavulanic acid or sulbactam

1 reference

12 December 2020

Elimination of plasmids from Enterobacteriaceae by 4-quinolone derivatives.

1 reference

12 December 2020

In-vitro activity of newer quinolones against aerobic bacteria.

1 reference

12 December 2020

In vitro activity of fosfomycin combined with rifampin, pefloxacin and imipenem against staphylococci: a study by the time-kill curve method

1 reference

12 December 2020

In vitro comparison of A-56619, A-56620, amifloxacin, ciprofloxacin, enoxacin, norfloxacin, and ofloxacin against methicillin-resistant Staphylococcus aureus

1 reference

12 December 2020

Neurological toxicity related to pefloxacin

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12 December 2020

Influence of beta-lactam antibiotics and ciprofloxacin on cell envelope of Escherichia coli

1 reference

12 December 2020

[Pefloxacine: diffusion into bronchial mucus]

1 reference

12 December 2020

In vitro activities of U-63366, a spectinomycin analog; roxithromycin (RU 28965), a new macrolide antibiotic; and five quinolone derivatives against Haemophilus ducreyi

1 reference

12 December 2020

[New oral quinolone compounds in chronic bronchitis]

1 reference

12 December 2020

Recovery of pefloxacin in saliva and feces and its action on oral and fecal floras of healthy volunteers

1 reference

12 December 2020

Efficacy of pefloxacin-fosfomycin in experimental endocarditis caused by methicillin-resistant Staphylococcus aureus

1 reference

12 December 2020

The comparative in-vitro activity of twelve 4-quinolone antimicrobials against Haemophilus ducreyi

1 reference

12 December 2020

Susceptibility of Legionella spp. to quinolone derivatives and related organic acids

1 reference

12 December 2020

4-Quinolone drugs affect cell cycle progression and function of human lymphocytes in vitro

1 reference

12 December 2020

[In vitro antibacterial activity of cefpirome in combination with 4 aminoglycosides and 2 fluoroquinolones].

1 reference

12 December 2020

Elimination of plasmids by new 4-quinolones

1 reference

12 December 2020

[Susceptibility of Campylobacter pyloridis to antibiotics]

1 reference

12 December 2020

Enoxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

1 reference

12 December 2020

Comparison of antimicrobial susceptibility patterns of fifty-seven strains of Haemophilus ducreyi isolated in Amsterdam from 1978 to 1985.

1 reference

12 December 2020

Pefloxacin kinetics in cirrhosis

1 reference

12 December 2020

Photoonycholysis induced by the fluoroquinolones pefloxacine and ofloxacine. Report on 2 cases

1 reference

12 December 2020

Prevention of bacterial infections after bone marrow graft by broad-spectrum oral antibiotics, absorbable (pefloxacin, penicillin) and non absorbable (cephalosporin, gentamycin, bacitracin)

1 reference

12 December 2020

[Intraocular penetration of pefloxacin in man and rabbit. The aqueous humor and vitreous body]

1 reference

12 December 2020

Comparative evaluation of recently developed quinolone compounds--with a note on the frequency of resistant mutants.

1 reference

12 December 2020

Comparative in vitro activity of seven quinolones against 100 clinical isolates of Clostridium difficile

1 reference

12 December 2020

Quinolones and colonization resistance in human volunteers.

1 reference

12 December 2020

In-vitro activity of pefloxacin compared to enoxacin, norfloxacin, gentamicin and new beta-lactams.

1 reference

12 December 2020

Comparative in vitro activity of ciprofloxacin, ofloxacin and pefloxacin against resistant clinical isolates.

1 reference

12 December 2020

Comparative in vitro activity of the new quinolone fleroxacin (RO 23-6240).

1 reference

12 December 2020

Comparative pharmacokinetic parameters of new systemic fluoroquinolones: a review

1 reference

12 December 2020

Comparative in vitro activities of pefloxacin, ofloxacin, enoxacin and ciprofloxacin against 256 clinical isolates

1 reference

12 December 2020

[Sensitivity of 7 mycobacterial species to new quinolones]

1 reference

12 December 2020

In vitro activity of pefloxacin.

1 reference

12 December 2020

The influence of quinolone derivatives on theophylline clearance

1 reference

12 December 2020

Comparative efficacy of pefloxacin and six other antimicrobial agents on Staphylococcus aureus experimental abscesses.

1 reference

12 December 2020

In vitro activity of lomefloxacin (SC-47111; NY-198), a difluoroquinolone 3-carboxylic acid, compared with those of other quinolones

1 reference

12 December 2020

Ofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

1 reference

12 December 2020

Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

1 reference

12 December 2020

Mechanisms of action of and resistance to ciprofloxacin

1 reference

12 December 2020

[Tolerance to pefloxacine during treatment of a series of osteoarticular infections. 36 cases]

1 reference

12 December 2020

Influence of two quinolones, ofloxacin and pefloxacin, on human myelopoiesis in vitro

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12 December 2020

Penetration of ciprofloxacin into cerebrospinal fluid of patients with bacterial meningitis

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12 December 2020

Comparative effects of quinolones on human mononuclear leucocyte functions

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12 December 2020

Improved high-performance liquid chromatographic determination of pefloxacin and its metabolite norfloxacin in human plasma and tissue

1 reference

12 December 2020

In vitro activity of antimicrobial agents against Acinetobacter calcoaceticus.

1 reference

12 December 2020

[Sensitivity of obligate anaerobes to ofloxacin, pefloxacin, enoxacin and norfloxacin]

1 reference

12 December 2020

Activities of pefloxacin and ciprofloxacin against Mycobacterium leprae in the mouse

1 reference

12 December 2020

In vitro activity of pefloxacin against gram-negative and gram-positive bacteria in comparison with other antibiotics

1 reference

12 December 2020

Peritonitis during continuous ambulatory peritoneal dialysis. Treatment with pefloxacin: first results and pharmacokinetics

1 reference

12 December 2020

Oral pharmacokinetics and ascitic fluid penetration of pefloxacin in cirrhosis

1 reference

12 December 2020

Clinical pharmacokinetics of the newer antibacterial 4-quinolones

1 reference

12 December 2020

Clinical uses of nalidixic acid analogues: the fluoroquinolones

1 reference

12 December 2020

Resistance occurring after fluoroquinolone therapy of experimental Pseudomonas aeruginosa peritonitis

1 reference

12 December 2020

Decreased absorption of pefloxacin by gastric antacids. Preliminary study

1 reference

12 December 2020

[Comparative in vitro antistaphylococcal effect of norfloxacin and pefloxacin on 312 hospital strains]

1 reference

12 December 2020

Pharmacokinetics of pefloxacin after repeated intravenous and oral administration (400 mg bid) in young healthy volunteers

1 reference

12 December 2020

[Kinetics of pefloxacin diffusion in human bone tissue following a single infusion of 800 mg. Evaluation of an extraction technic using chloroform]

1 reference

12 December 2020

Efficacy of pefloxacin in comparison with erythromycin in the treatment of experimental guinea pig legionellosis

1 reference

12 December 2020

Comparative efficacy of five antibiotics on experimental airborne legionellosis in guinea-pigs

1 reference

12 December 2020

Comparative bactericidal kinetics of ciprofloxacin, ofloxacin and pefloxacin alone and in combination against strains of group D Streptococcus

1 reference

12 December 2020

In vitro susceptibility of 96 Capnocytophaga strains, including a beta-lactamase producer, to new beta-lactam antibiotics and six quinolones

1 reference

12 December 2020

Nalidixic acid-resistant mutations of the gyrB gene of Escherichia coli

1 reference

12 December 2020

The quinolones in chronic bronchitis

1 reference

12 December 2020

Penetration of pefloxacin into cerebrospinal fluid of patients with meningitis

1 reference

12 December 2020

Pefloxacin in rabbits: protein binding, extravascular diffusion, urinary excretion and bactericidal effect in experimental endocarditis

1 reference

12 December 2020

Effects of pefloxacin on phagocytosis function of rat macrophages and polymorphonuclear leucocytes

1 reference

12 December 2020

Resistance to ten different fluoroquinolone antibiotics following in vitro exposures to nalidixic acid

1 reference

12 December 2020

Pefloxacin concentrations in human aqueous humour and lens

1 reference

12 December 2020

[In vitro activity of 3 fluoroquinolones on Branhamella catarrhalis]

1 reference

12 December 2020

Dose-dependent pharmacokinetic study of pefloxacin, a new antibacterial agent, in humans

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12 December 2020

Pharmacokinetics of pefloxacin in renal insufficiency

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12 December 2020

Transfer kinetics of pefloxacin into cerebro-spinal fluid after one hour i.v. infusion of 400 mg in man.

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12 December 2020

Pharmacokinetics and tissue penetration of orally administered pefloxacin

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12 December 2020

Activity of pefloxacin and thirteen other antimicrobial agents in vitro against isolates from hospital and genitourinary infections.

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12 December 2020

Absorption, distribution, metabolic fate, and elimination of pefloxacin mesylate in mice, rats, dogs, monkeys, and humans

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12 December 2020

The in-vitro comparative activity of quinolones against bacteria from urinary tract infections in general practice.

1 reference

12 December 2020

Norfloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

1 reference

12 December 2020

Susceptibility of non-fermentative gram-negative bacteria to ciprofloxacin, norfloxacin, amifloxacin, pefloxacin and cefpirome

1 reference

12 December 2020

The comparative activity of pefloxacin, enoxacin, ciprofloxacin and 13 other antimicrobial agents against enteropathogenic microorganisms

1 reference

12 December 2020

In vitro activities of five new quinolones against 88 genital and neonatal Haemophilus isolates

1 reference

12 December 2020

Susceptibility of multiply resistant Haemophilus influenzae to newer antimicrobial agents.

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12 December 2020

Comparative in vitro studies with 4-quinolone antimicrobials

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12 December 2020

In-vitro activity of pefloxacin against micro-organisms multiply resistant to beta-lactam antibiotics and aminoglycosides.

1 reference

12 December 2020

[In vitro activity of new quinolones against Mycoplasma pathogenic to humans].

1 reference

12 December 2020

Bactericidal activity and killing rate of serum in volunteers receiving pefloxacin alone or in combination with ceftazidime, piperacillin or mezlocillin against Pseudomonas aeruginosa.

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12 December 2020

Penetration of pefloxacin in human heart valves.

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12 December 2020

In vitro antibacterial activity of piperacillin/quinolone combinations

1 reference

12 December 2020

Susceptibility of Campylobacter pyloridis to 20 antimicrobial agents

1 reference

12 December 2020

The comparative in-vitro activity of pefloxacin.

1 reference

12 December 2020

The diffusion of pefloxacin into bone and the treatment of osteomyelitis

1 reference

12 December 2020

[The effect of pefloxacin on the chemotactic response of human polynuclear neutrophils after oral treatment]

1 reference

12 December 2020

Comparative in vitro activities of six new fluoroquinolones and other oral antimicrobial agents against Campylobacter pylori

1 reference

12 December 2020

New 4-quinolones in the treatment of urinary tract infections.

1 reference

12 December 2020

Mutational resistance to 4-quinolone antibacterial agents

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12 December 2020

Bactericidal activity and killing rate of serum from volunteers receiving pefloxacin alone or in combination with amikacin

1 reference

12 December 2020

10.2165/00003495-198937050-00003

Identifiers

DOI

1 reference

PubMed ID

2663414

Dimensions Publication ID

3 August 2017

0 references

1 reference

PubMed ID

2663414