(Q34674753)

3 August 2017

1 reference

title

Mono-N-terminal poly(ethylene glycol)-protein conjugates (English)

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3 August 2017

Olaf Kinstler

1

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3 August 2017

Graham Molineux

2

1 reference

3 August 2017

Michael Treuheit

3

1 reference

3 August 2017

David Ladd

4

1 reference

3 August 2017

Colin Gegg

5

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3 August 2017

language of work or name

English

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publication date

1 June 2002

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Advanced Drug Delivery Reviews

3 August 2017

published in

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3 August 2017

volume

54

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3 August 2017

issue

4

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3 August 2017

page(s)

477-485

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Therapeutic antibody fragments with prolonged in vivo half-lives

3 August 2017

cites work

1 reference

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7 January 2021

Transglutaminase-mediated dual and site-specific incorporation of poly(ethylene glycol) derivatives into a chimeric interleukin-2

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7 January 2021

Site-specific attachment of functionalized poly(ethylene glycol) to the amino terminus of proteins

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7 January 2021

Single-chain Fv with manifold N-glycans as bifunctional scaffolds for immunomolecules

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7 January 2021

Use of site-directed mutagenesis to enhance the epitope-shielding effect of covalent modification of proteins with polyethylene glycol

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7 January 2021

Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and immunogenicity

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7 January 2021

Functionalized Poly(ethylene glycols) for Preparation of Biologically Relevant Conjugates

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7 January 2021

Rational design of a potent, long-lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon alpha-2a for the treatment of hepatitis C.

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7 January 2021

"Hairy enzymes" stay in the blood

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7 January 2021

Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: a comparison of conjugation chemistries and compounds

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7 January 2021

Synthesis and Physicochemical Properties of Protein Conjugates with Water-Soluble Poly(alkylene oxides)

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7 January 2021

Polyethylene glycol (PEG) modification of granulocyte-macrophage colony stimulating factor (GM-CSF) enhances neutrophil priming activity but not colony stimulating activity

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7 January 2021

Improvement of oxygen-carrying properties of human hemoglobin by chemical modification with a benzene hexacarboxylate-monosubstituted polyoxyethylene

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7 January 2021

Structure-function studies of interleukin 15 using site-specific mutagenesis, polyethylene glycol conjugation, and homology modeling

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7 January 2021

Subtiligase: a tool for semisynthesis of proteins

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7 January 2021

A general method for highly selective cross-linking of unprotected polypeptides via pH-controlled modification of N-terminal alpha-amino groups

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7 January 2021

Site-directed pegylation of recombinant interleukin-2 at its glycosylation site

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7 January 2021

Labeling glycoconjugates with hydrazide reagents

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7 January 2021

Studies on the rate and control of antibody oxidation by periodate

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7 January 2021

Modification of CD4 immunoadhesin with monomethoxypoly(ethylene glycol) aldehyde via reductive alkylation

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7 January 2021

Characterization and stability of N-terminally PEGylated rhG-CSF.

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7 January 2021

A new form of Filgrastim with sustained duration in vivo and enhanced ability to mobilize PBPC in both mice and humans

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7 January 2021

Effects of renal function on pharmacokinetics of recombinant human granulocyte colony-stimulating factor in lung cancer patients.

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7 January 2021

Randomized, dose-escalation study of SD/01 compared with daily filgrastim in patients receiving chemotherapy

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7 January 2021

Demonstration and some properties of human thrombopoietin in thrombocythaemic sera

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7 January 2021

Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

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7 January 2021

Purification and characterization of thrombopoietin

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7 January 2021

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand.

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7 January 2021

The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production

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7 January 2021

Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl.

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7 January 2021

Regulation of Platelet Production: ‘Hypersplenism’ in the Experimental Animal

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7 January 2021

Pharmacokinetic analysis of pegylated megakaryocyte growth and development factor in humans

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7 January 2021

PEGylation prevents the N-terminal degradation of megakaryocyte growth and development factor

1 reference

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7 January 2021

10.1016/S0169-409X(02)00023-6

Identifiers

DOI

1 reference

3 August 2017

1 reference