(Q34675229)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25146929%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes (English)

1 reference

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13 March 2020

6

1 reference

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13 March 2020

Margus Pooga

9

1 reference

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13 March 2020

Julian Pardo

10

1 reference

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13 March 2020

author name string

S S Metkar

1

1 reference

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13 March 2020

M Marchioretto

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25146929%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

V Antonini

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25146929%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

L Lunelli

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25146929%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

B Wang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25146929%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

G Anderluh

7

1 reference

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13 March 2020

R Roth

8

1 reference

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13 March 2020

J E Heuser

11

1 reference

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13 March 2020

M D Serra

12

1 reference

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13 March 2020

C J Froelich

13

1 reference

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13 March 2020

publication date

22 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25146929%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

13 March 2020

published in

1 reference

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13 March 2020

volume

22

1 reference

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13 March 2020

issue

1

1 reference

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13 March 2020

page(s)

74-85

1 reference

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https://scigraph.springernature.com/pub.10.1038/cdd.2014.110

13 March 2020

exact match

0 references

cites work

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Functional truncated membrane pores

7 July 2018

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Effects of MACPF/CDC proteins on lipid membranes.

7 July 2018

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Packing a punch: the mechanism of pore formation by cholesterol dependent cytolysins and membrane attack complex/perforin-like proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC)

7 July 2018

1 reference

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Perforin activity at membranes leads to invaginations and vesicle formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Perforin rapidly induces plasma membrane phospholipid flip-flop

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Imaging of lytic granule exocytosis in CD8+ cytotoxic T lymphocytes reveals a modified form of full fusion

7 July 2018

1 reference

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Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membrane

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

The structural basis for membrane binding and pore formation by lymphocyte perforin

7 July 2018

1 reference

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Human perforin employs different avenues to damage membranes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis

7 July 2018

1 reference

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Cytosolic delivery of liposomally targeted proteins induced by photochemical internalization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Detection of human perforin by ELISpot and ELISA: ex vivo identification of virus-specific cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Melittin-induced bilayer leakage depends on lipid material properties: evidence for toroidal pores

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Effect of pH on the conformation, interaction with membranes and hemolytic activity of sticholysin II, a pore forming cytolysin from the sea anemone Stichodactyla helianthus.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Human perforin: rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays

7 July 2018

1 reference

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Neutron scattering in the plane of membranes: structure of alamethicin pores

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Changes in intracellular calcium concentration and pH of target cells during the cytotoxic process: A quantitative study at the single cell level

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

A voltage-gated ion channel model inferred from the crystal structure of alamethicin at 1.5-Å resolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Quantitation of intracellular free calcium in single adult cardiomyocytes by fura-2 fluorescence microscopy: calibration of fura-2 ratios

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Transients of perforin pore formation observed by fluorescence microscopic single channel recording

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4262768

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.110

A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.

21 January 2018

1 reference

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Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

21 January 2018

1 reference

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Chemically induced phospholipid translocation across biological membranes

21 January 2018

1 reference

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An antimicrobial peptide, magainin 2, induced rapid flip-flop of phospholipids coupled with pore formation and peptide translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2014.110

Pore formation by equinatoxin II, a eukaryotic protein toxin, occurs by induction of nonlamellar lipid structures

21 January 2018

1 reference

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Penetration without cells: membrane translocation of cell-penetrating peptides in the model giant plasma membrane vesicles.

21 January 2018

1 reference

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A Comprehensive Model for the Cellular Uptake of Cationic Cell-penetrating Peptides

21 January 2018

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Liposomes in the Study of Pore-Forming Toxins

21 January 2018

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Flow cytometric analysis of murine splenic B lymphocyte cytosolic free calcium response to anti-IgM and anti-IgD

21 January 2018

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12 December 2020

Rapid purification of cationic granule proteases: application to human granzymes

1 reference

12 December 2020

New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis

1 reference

12 December 2020

Direct evidence for membrane pore formation by the apoptotic protein Bax

1 reference

12 December 2020

Effect of lipids with different spontaneous curvature on the channel activity of colicin E1: evidence in favor of a toroidal pore

1 reference

12 December 2020

Lipid dependence of the channel properties of a colicin E1-lipid toroidal pore

1 reference

12 December 2020

Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH

1 reference

12 December 2020

Identifiers

DOI

10.1038/CDD.2014.110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25146929%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25146929%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

25146929

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25146929%20AND%20SRC:MED&resulttype=core&format=json