(Q24301586)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

title

Human perforin employs different avenues to damage membranes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

0 references

1 reference

GOA release 2020-03-11

protein homooligomerization

1 reference

GOA release 2020-03-11

author

Gabriella Viero

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Aleš Kladnik

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Gregor Anderluh

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Mauro Dalla Serra

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Robert J Gilbert

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

author name string

Tilen Praper

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Andreas Sonnen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

Christopher J Froelich

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

language of work or name

English

0 references

publication date

2 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

number of pages

10

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

volume

286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

issue

4

1 reference

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14 February 2020

page(s)

2946-2955

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins

14 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

19 March 2017

1 reference

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An antimicrobial activity of cytolytic T cells mediated by granulysin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

UCSF Chimera--a visualization system for exploratory research and analysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Accurate determination of local defocus and specimen tilt in electron microscopy

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

EMAN: semiautomated software for high-resolution single-particle reconstructions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Plasmodium berghei: plasmodium perforin-like protein 5 is required for mosquito midgut invasion in Anopheles stephensi

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

A new generation of the IMAGIC image processing system

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Structural basis of pore formation by the bacterial toxin pneumolysin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Barrel-stave model or toroidal model? A case study on melittin pores.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Enhanced genome annotation using structural profiles in the program 3D-PSSM

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Exploring the extremes of sequence/structure space with ensemble fold recognition in the program Phyre

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Reverse genetics screen identifies six proteins important for malaria development in the mosquito

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

The biological significance of lipid-protein interactions.

26 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

The molecular basis for perforin oligomerization and transmembrane pore assembly

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Disparate proteins use similar architectures to damage membranes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

The MACPF/CDC family of pore-forming toxins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Effect of the structure of lipids favoring disordered domain formation on the stability of cholesterol-containing ordered domains (lipid rafts): identification of multiple raft-stabilization mechanisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Delivering the kiss of death: progress on understanding how perforin works

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Perforin-mediated target-cell death and immune homeostasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Inactivation and activity of cholesterol-dependent cytolysins: what structural studies tell us.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Calcium-dependent plasma membrane binding and cell lysis by perforin are mediated through its C2 domain: A critical role for aspartate residues 429, 435, 483, and 485 but not 491.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Cholesterol and the activity of bacterial toxins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Assembly and topography of the prepore complex in cholesterol-dependent cytolysins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Assembly mechanism of the oligomeric streptolysin O pore: the early membrane lesion is lined by a free edge of the lipid membrane and is extended gradually during oligomerization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid-binding C2 domain.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Effect of changing the size of lipid headgroup on peptide insertion into membranes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Human perforin: rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Liposomes as targets for granule cytolysin from cytotoxic large granular lymphocyte tumors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Mechanism of membrane damage by streptolysin-O.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Extracellular release of lymphocyte cytolytic pore-forming protein (perforin) after ionophore stimulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Properties of a purified pore-forming protein (perforin 1) isolated from H-2-restricted cytotoxic T cell granules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Functional channel formation associated with cytotoxic T-cell granules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Functional size of complement and perforin pores compared by confocal laser scanning microscopy and fluorescence microphotolysis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Transients of perforin pore formation observed by fluorescence microscopic single channel recording

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Demonstration of a cholesterol-dependent cytolysin in a noninsecticidal Bacillus sphaericus strain and evidence for widespread distribution of the toxin within the species

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Toxin structure: part of a hole?

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Ion modulation of membrane permeability: effect of cations on intact cells and on cells and phospholipid bilayers treated with pore-forming agents

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Cell damage by cytolysin. Spontaneous recovery and reversible inhibition by divalent cations.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Electroformation in a flow chamber with solution exchange as a means of preparation of flaccid giant vesicles.

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.169417

Pneumolysin generates multiple conductance pores in the membrane of nucleated cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.169417

Vibrio cholerae hemolysin. Implication of amphiphilicity and lipid-induced conformational change for its pore-forming activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.169417

Host cell traversal is important for progression of the malaria parasite through the dermis to the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.169417

The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.169417

Characterization of molecular properties of pore-forming toxins with planar lipid bilayers

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024789

Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells

29 November 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.169417

Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH

21 January 2018

1 reference

12 December 2020

Differential sensitivity of pneumolysin-induced channels to gating by divalent cations

1 reference

12 December 2020

The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins

1 reference

12 December 2020

Isolation of a lytic, pore-forming protein (perforin) from cytolytic T-lymphocytes

1 reference

12 December 2020

Perforin-mediated myocardial damage in acute myocarditis

1 reference

12 December 2020

Interaction of the pore-forming protein equinatoxin II with model lipid membranes: A calorimetric and spectroscopic study

1 reference

12 December 2020

Cholesterol and the activity of bacterial toxins

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.169417

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20889983%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

20889983

2 references