(Q34675649)

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A dileucine in the protease of botulinum toxin A underlies its long-lived neuroparalysis: transfer of longevity to a novel potential therapeutic

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Europe PubMed Central

PubMed publication ID

3 August 2017

A dileucine in the protease of botulinum toxin A underlies its long-lived neuroparalysis: transfer of longevity to a novel potential therapeutic (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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Jiafu Wang

1

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David P Finn

6

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author name string

Tomas H Zurawski

2

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Jianghui Meng

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Gary Lawrence

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Weredeselam M Olango

5

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Larry Wheeler

7

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Europe PubMed Central

PubMed publication ID

3 August 2017

J Oliver Dolly

8

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Europe PubMed Central

PubMed publication ID

3 August 2017

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publication date

7 December 2010

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Europe PubMed Central

PubMed publication ID

3 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

3 August 2017

286

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Europe PubMed Central

PubMed publication ID

3 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

6375-6385

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

OnabotulinumtoxinA for treatment of chronic migraine: pooled results from the double-blind, randomized, placebo-controlled phases of the PREEMPT clinical program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Botulinum neurotoxin: a marvel of protein design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

A distributed set of interactions controls mu2 functionality in the role of AP-2 as a sorting adaptor in synaptic vesicle endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

The biological activity of ubiquitinated BoNT/B light chain in vitro and in human SHSY-5Y neuronal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Electroacupuncture suppresses capsaicin-induced secondary hyperalgesia through an endogenous spinal opioid mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Neuro-exocytosis: botulinum toxins as inhibitory probes and versatile therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Mechanisms involved in an increment of multimodal excitability of medullary and upper cervical dorsal horn neurons following cutaneous capsaicin treatment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Novel chimeras of botulinum neurotoxins A and E unveil contributions from the binding, translocation, and protease domains to their functional characteristics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Single molecule detection of intermediates during botulinum neurotoxin translocation across membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Exploding vs. imploding headache in migraine prophylaxis with Botulinum Toxin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Antinociceptive effect of antisense oligonucleotides against the vanilloid receptor VR1/TRPV1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

SV2 is the protein receptor for botulinum neurotoxin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Protein production by auto-induction in high density shaking cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Plasma membrane localization signals in the light chain of botulinum neurotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Evaluation of the therapeutic usefulness of botulinum neurotoxin B, C1, E, and F compared with the long lasting type A. Basis for distinct durations of inhibition of exocytosis in central neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Intramuscular and intradermal injection of capsaicin: a comparison of local and referred pain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Interaction of 125I-labeled botulinum neurotoxins with nerve terminals. II. Autoradiographic evidence for its uptake into motor nerves by acceptor-mediated endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Effects of botulinum toxin on neuromuscular transmission in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

7 July 2018

Activation of TRPV1 mediates calcitonin gene-related peptide release, which excites trigeminal sensory neurons and is attenuated by a retargeted botulinum toxin with anti-nociceptive potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

26 October 2018

Two protein trafficking processes at motor nerve endings unveiled by botulinum neurotoxin E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

26 October 2018

Antiepileptic effects of botulinum neurotoxin E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

26 October 2018

Botulinum neurotoxin type D enables cytosolic delivery of enzymatically active cargo proteins to neurones via unfolded translocation intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

26 October 2018

Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

26 October 2018

Ca2+-induced changes in SNAREs and synaptotagmin I correlate with triggered exocytosis from chromaffin cells: insights gleaned into the signal transduction using trypsin and botulinum toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

26 October 2018

Persistence of botulinum neurotoxin A demonstrated by sequential administration of serotypes A and E in rat EDL muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

26 October 2018

Different time courses of recovery after poisoning with botulinum neurotoxin serotypes A and E in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3057784

26 October 2018

A comparison of the safety margins of botulinum neurotoxin serotypes A, B, and F in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21138836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of motor nerve terminal remodeling unveiled using SNARE-cleaving botulinum toxins: the extent and duration are dictated by the sites of SNAP-25 truncation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21138836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potency of 3,4-Diaminopyridine and 4-aminopyridine on mammalian neuromuscular transmission and the effect of pH changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21138836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acceptors for botulinum neurotoxin reside on motor nerve terminals and mediate its internalization

1 reference

https://pubmed.ncbi.nlm.nih.gov/21138836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of the constituent chains of botulinum neurotoxins A and B in the blockade of neurotransmitter release

1 reference

https://pubmed.ncbi.nlm.nih.gov/21138836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human response to botulinum toxin injection: type B compared with type A

1 reference

https://pubmed.ncbi.nlm.nih.gov/21138836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistence of botulinum neurotoxin action in cultured spinal cord cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21138836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptobrevin I mediates exocytosis of CGRP from sensory neurons and inhibition by botulinum toxins reflects their anti-nociceptive potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/21138836

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.181784

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

release_6z2yf7ygzvhe7nkeiv6ga5en74

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https://api.fatcat.wiki/v0/release/6z2yf7ygzvhe7nkeiv6ga5en74

24 November 2022

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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