(Q34675885)

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Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy (English)

1 reference

Europe PubMed Central

3 August 2017

Huntington's disease

0 references

13

object named as

Isaac S Kohane

1 reference

Europe PubMed Central

3 August 2017

James F. Gusella

16

object named as

James F Gusella

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Europe PubMed Central

3 August 2017

6

object named as

Tammy Gillis

1 reference

Europe PubMed Central

3 August 2017

Marcy E. MacDonald

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object named as

Marcy E MacDonald

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Europe PubMed Central

3 August 2017

Vanessa C Wheeler

15

object named as

Vanessa C Wheeler

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Europe PubMed Central

3 August 2017

14

object named as

Ihn Sik Seong

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Europe PubMed Central

3 August 2017

Jayalakshmi Srinidhi Mysore

7

object named as

Jayalakshmi Srinidhi Mysore

1 reference

Europe PubMed Central

3 August 2017

4

object named as

Elisa Fossale

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Europe PubMed Central

3 August 2017

Kathryn R Coser

8

object named as

Kathryn R Coser

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Europe PubMed Central

3 August 2017

9

object named as

Toshi Shioda

1 reference

Europe PubMed Central

3 August 2017

author name string

Jong-Min Lee

1

1 reference

Europe PubMed Central

3 August 2017

Ekaterina I Galkina

2

1 reference

Europe PubMed Central

3 August 2017

Rachel M Levantovsky

3

1 reference

Europe PubMed Central

3 August 2017

Mary Anne Anderson

5

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Europe PubMed Central

3 August 2017

Bin Zhang

10

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Europe PubMed Central

3 August 2017

Matthew D Furia

11

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Europe PubMed Central

3 August 2017

Jonathan Derry

12

1 reference

Europe PubMed Central

3 August 2017

publication date

16 April 2013

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Europe PubMed Central

3 August 2017

Human Molecular Genetics

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Europe PubMed Central

3 August 2017

22

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3 August 2017

16

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3 August 2017

3227-3238

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Europe PubMed Central

3 August 2017

CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

HD CAG-correlated gene expression changes support a simple dominant gain of function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Prevalence of incompletely penetrant Huntington's disease alleles among individuals with major depressive disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Huntingtin facilitates polycomb repressive complex 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Genetics of gene expression and its effect on disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Analysis of potential transcriptomic biomarkers for Huntington's disease in peripheral blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: the HD MAPS study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Adjusting batch effects in microarray expression data using empirical Bayes methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Regional and cellular gene expression changes in human Huntington's disease brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Exploiting naturally occurring DNA variation and molecular profiling data to dissect disease and drug response traits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Discovering statistically significant pathways in expression profiling studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

An integrative genomics approach to infer causal associations between gene expression and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Comparison of ARM and HEAT protein repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Trinucleotide repeat length instability and age of onset in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Structure and expression of the Huntington's disease gene: evidence against simple inactivation due to an expanded CAG repeat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Increased rate of suicide among patients with Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3723309

7 July 2018

Estimating the probability of de novo HD cases from transmissions of expanded penetrant CAG alleles in the Huntington disease gene from male carriers of high normal alleles (27-35 CAG).

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT176

21 January 2018

A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT176

21 January 2018

Huntington's disease CAG trinucleotide repeats in pathologically confirmed post-mortem brains

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT176

21 January 2018

HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT176

21 January 2018

Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT176

21 January 2018

Differential 3' polyadenylation of the Huntington disease gene results in two mRNA species with variable tissue expression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT176

21 January 2018

A new polymerase chain reaction (PCR) assay for the trinucleotide repeat that is unstable and expanded on Huntington's disease chromosomes

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT176

21 January 2018

Re: Autopsy-proven Huntington's disease with 29 trinucleotide repeats

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDT176

21 January 2018

Identifiers

10.1093/HMG/DDT176

1 reference

Europe PubMed Central

3 August 2017

release_kahjiyh3t5dgtiztjjbezmadrm

1 reference

https://api.fatcat.wiki/v0/release/kahjiyh3t5dgtiztjjbezmadrm

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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