(Q34675945)

3 August 2017

title

Pivotal role of mouse mast cell protease 4 in the conversion and pressor properties of Big-endothelin-1. (English)

1 reference

3 August 2017

0 references

Martin Houde

1

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Gunnar Pejler

5

object named as

Gunnar Pejler

1 reference

3 August 2017

Pedro D'Orléans-Juste

8

object named as

Pedro D'Orléans-Juste

1 reference

3 August 2017

Marc-David Jamain

2

1 reference

3 August 2017

Julie Labonté

3

1 reference

3 August 2017

Louisane Desbiens

4

1 reference

3 August 2017

Michael Gurish

6

1 reference

3 August 2017

Shinji Takai

7

1 reference

3 August 2017

language of work or name

English

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publication date

17 April 2013

1 reference

Journal of Pharmacology and Experimental Therapeutics

3 August 2017

published in

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3 August 2017

volume

346

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3 August 2017

issue

1

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3 August 2017

page(s)

31-37

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Targets of chymase inhibitors

3 August 2017

cites work

1 reference

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Chymase as an Important Target for Preventing Complications of Metabolic Syndrome

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Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation

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7 July 2018

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Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation

7 July 2018

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7 July 2018

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The extended cleavage specificity of the rodent beta-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymase

7 July 2018

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7 July 2018

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7 July 2018

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The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover

7 July 2018

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7 July 2018

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7 July 2018

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Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development

7 July 2018

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Long-term telemetric recording of arterial pressure and heart rate in mice fed basal and high NaCl diets

7 July 2018

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Endothelin generating pathway through endothelin1-31 in human cultured bronchial smooth muscle cells

7 July 2018

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Effect of endothelin-1 (1-31) on extracellular signal-regulated kinase and proliferation of human coronary artery smooth muscle cells

7 July 2018

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Selective conversion of big endothelins to tracheal smooth muscle-constricting 31-amino acid-length endothelins by chymase from human mast cells

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

7 July 2018

1 reference

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Cloning and expression of a cDNA encoding an endothelin receptor

7 July 2018

1 reference

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Phosphoramidon blocks the pressor activity of porcine big endothelin-1-(1-39) in vivo and conversion of big endothelin-1-(1-39) to endothelin-1-(1-21) in vitro

7 July 2018

1 reference

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Effects of chymase inhibitor on angiotensin II-induced abdominal aortic aneurysm development in apolipoprotein E-deficient mice

7 July 2018

1 reference

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Chymase-dependent conversion of Big endothelin-1 in the mouse in vivo

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684843

Chymase inhibition reduces the progression to heart failure after autoimmune myocarditis in rats

26 October 2018

1 reference

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26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684843

Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684843

Endothelin-1(1-31) levels are increased in atherosclerotic lesions of the thoracic aorta of hypercholesterolemic hamsters

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684843

A specific chymase inhibitor, 2-(5-formylamino-6-oxo-2-phenyl-1,6-dihydropyrimidine-1-yl)-N-[[3,4-dioxo-1-phenyl-7-(2-pyridyloxy)]-2-heptyl]acetamide (NK3201), suppresses development of abdominal aortic aneurysm in hamsters

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684843

Impact of chymase inhibitor on cardiac function and survival after myocardial infarction

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684843

Endothelin-A receptors mediate renal hemodynamic effects of exogenous Angiotensin II in humans

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684843

A novel chymase inhibitor, 4-[1-([bis-(4-methyl-phenyl)-methyl]-carbamoyl)3-(2-ethoxy-benzyl)-4-oxo-azetidine-2-yloxy]-benzoic acid (BCEAB), suppressed cardiac fibrosis in cardiomyopathic hamsters

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684843

Identification of a stable chymase inhibitor using a pharmacophore-Based database search

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684843

Long-term telemetric measurement of cardiovascular parameters in awake mice: a physiological genomics tool.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3684843

Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor

26 October 2018

1 reference

12 December 2020

Angiotensin II induces nuclear factor- kappa B activation in cultured neonatal rat cardiomyocytes through protein kinase C signaling pathway

1 reference

12 December 2020

Stress upregulates arterial matrix metalloproteinase expression and activity via endothelin A receptor activation

1 reference

12 December 2020

Role of mast cell chymase in the extracellular processing of big-endothelin-1 to endothelin-1 in the perfused rat lung

1 reference

12 December 2020

Vasoconstrictor action of angiotensin I-convertase and the synthetic substrate (Pro11,D-Ala12)-angiotensin I

1 reference

12 December 2020

Accumulation of activated mast cells in the shoulder region of human coronary atheroma, the predilection site of atheromatous rupture

1 reference

12 December 2020

Processing of proendothelin-1 by human furin convertase

1 reference

12 December 2020

Localization of neutral endopeptidase (NEP) mRNA in human bronchi

1 reference

12 December 2020

Hydrolysis of big endothelin-1 by a serine protease in the membrane fraction of human lung

1 reference

12 December 2020

Identifiers

DOI

10.1124/JPET.112.202275

1 reference

3 August 2017

1 reference

3 August 2017

1 reference