(Q34679829)

3 August 2017

title

Rapamycin inhibits anal carcinogenesis in two preclinical animal models (English)

1 reference

3 August 2017

1 reference

1 reference

Gregory D Kennedy

5

0 references

Henry C Pitot

2

object named as

Henry C Pitot

1 reference

3 August 2017

Marie K Stelzer

1

1 reference

3 August 2017

Amy Liem

3

1 reference

3 August 2017

Denis Lee

4

1 reference

3 August 2017

Paul F Lambert

6

1 reference

3 August 2017

publication date

1 December 2010

1 reference

Cancer Prevention Research

3 August 2017

published in

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3 August 2017

volume

3

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3 August 2017

issue

12

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3 August 2017

page(s)

1542-1551

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A mouse model for human anal cancer

3 August 2017

cites work

1 reference

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Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status

7 July 2018

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Human papillomavirus type 16 E6 and E7 oncoproteins act synergistically to cause head and neck cancer in mice

7 July 2018

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7 July 2018

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A role for HPV16 E5 in cervical carcinogenesis

7 July 2018

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Evaluating temsirolimus activity in multiple tumors: a review of clinical trials

7 July 2018

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7 July 2018

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Human papillomavirus E7 oncoprotein overrides the tumor suppressor activity of p21Cip1 in cervical carcinogenesis

7 July 2018

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Rapamycin prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model.

7 July 2018

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Persistence of high-grade cervical dysplasia and cervical cancer requires the continuous expression of the human papillomavirus type 16 E7 oncogene

7 July 2018

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Immunoregulatory functions of mTOR inhibition.

7 July 2018

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Human papillomavirus type distribution in anal cancer and anal intraepithelial lesions

7 July 2018

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Inhibition of mTOR radiosensitizes soft tissue sarcoma and tumor vasculature

7 July 2018

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Requirement for estrogen receptor alpha in a mouse model for human papillomavirus-associated cervical cancer

7 July 2018

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7 July 2018

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Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

7 July 2018

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p53 Loss synergizes with estrogen and papillomaviral oncogenes to induce cervical and breast cancers

7 July 2018

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Role of Rb-dependent and Rb-independent functions of papillomavirus E7 oncogene in head and neck cancer.

7 July 2018

1 reference

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Expression of an activated mammalian target of rapamycin in adenocarcinoma of the cervix: A potential biomarker and molecular target therapy

7 July 2018

1 reference

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mTOR is activated in the majority of malignant melanomas

7 July 2018

1 reference

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Antiproliferative effects of rapamycin as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines

7 July 2018

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Dissecting the Akt/mammalian target of rapamycin signaling network: emerging results from the head and neck cancer tissue array initiative.

7 July 2018

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Mammalian target of rapamycin inhibitors as possible adjuvant therapy for microscopic residual disease in head and neck squamous cell cancer

7 July 2018

1 reference

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HPV16 E6 confers p53-dependent and p53-independent phenotypes in the epidermis of mice deficient for E6AP.

7 July 2018

1 reference

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Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Growing roles for the mTOR pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

The minor capsid protein L2 contributes to two steps in the human papillomavirus type 31 life cycle.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Estrogen contributes to the onset, persistence, and malignant progression of cervical cancer in a human papillomavirus-transgenic mouse model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

The human papillomavirus type 16 E6 gene alone is sufficient to induce carcinomas in transgenic animals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogene.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Inhibition of T and B lymphocyte proliferation by rapamycin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Targeting mammalian target of rapamycin by rapamycin prevents tumor progression in an oral-specific chemical carcinogenesis model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Comparative analysis of cervical cancer in women and in a human papillomavirus-transgenic mouse model: identification of minichromosome maintenance protein 7 as an informative biomarker for human cervical cancer.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Rapamycin selectively inhibits the growth of childhood rhabdomyosarcoma cells through inhibition of signaling via the type I insulin-like growth factor receptor.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058330

Incidence of types of cancer among HIV-infected persons compared with the general population in the United States, 1992-2003

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21149330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of the immune response by rapamycin, a new antifungal antibiotic

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21149330

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1940-6207.CAPR-10-0228

1 reference

3 August 2017

1 reference

3 August 2017

1 reference