(Q34680927)

3 August 2017

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title

Genetic profile of acute myeloid leukemia (English)

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3 August 2017

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Cristina Mecucci

1

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3 August 2017

Roberto Rosati

series ordinal

2

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3 August 2017

Roberta La Starza

series ordinal

3

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3 August 2017

publication date

1 March 2002

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Reviews in Clinical and Experimental Hematology

3 August 2017

published in

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3 August 2017

volume

6

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3 August 2017

issue

1

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3 August 2017

page(s)

3-25; discussion 86-7

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The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

3 August 2017

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Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

21 January 2018

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Variant and masked translocations in acute promyelocytic leukemia.

21 January 2018

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Fusion of retinoic acid receptor alpha to NuMA, the nuclear mitotic apparatus protein, by a variant translocation in acute promyelocytic leukaemia

21 January 2018

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Prognostic significance of minimal residual disease detection and PML/RAR-alpha isoform type: long-term follow-up in acute promyelocytic leukemia

21 January 2018

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Recurrent granulocytic sarcoma. An unusual variation of acute myelogenous leukemia associated with 8;21 chromosomal translocation and blast expression of the neural cell adhesion molecule

21 January 2018

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Leukemogenesis by CBF oncoproteins

21 January 2018

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Molecular detection of t(8;21)/AML1-ETO in AML M1/M2: correlation with cytogenetics, morphology and immunophenotype

21 January 2018

1 reference

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AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

21 January 2018

1 reference

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Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia

21 January 2018

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The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene

21 January 2018

1 reference

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Translocation t(8;16)(p11;p13) in acute non-lymphocytic leukemia: report on two new cases and review of the literature.

21 January 2018

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The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

21 January 2018

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MOZ is fused to p300 in an acute monocytic leukemia with t(8;22).

21 January 2018

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MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).

21 January 2018

1 reference

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Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia

21 January 2018

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Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia

21 January 2018

1 reference

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Rapid and sensitive detection of all types of MLL gene translocations with a single FISH probe set.

21 January 2018

1 reference

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ALL-1 partial duplication in acute leukemia

21 January 2018

1 reference

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Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

In utero rearrangements in the trithorax-related oncogene in infant leukaemias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

The t(1;12)(q21;p13) translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

The EVI1 gene in myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Meiotic origin of trisomy in neoplasms: evidence in a case of erythroleukaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

c-myc amplification in a preleukemia patient with trisomy 4 and double minutes: review of the unique coexistence of these two chromosome abnormalities in acute myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

MLL2, the second human homolog of the Drosophila trithorax gene, maps to 19q13.1 and is amplified in solid tumor cell lines

21 January 2018

1 reference

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A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

21 January 2018

1 reference

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FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

A FLT3 tyrosine kinase inhibitor is selectively cytotoxic to acute myeloid leukemia blasts harboring FLT3 internal tandem duplication mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Inhibition of FLT3-mediated transformation by use of a tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

FLT3 tyrosine kinase as a target molecule for selective antileukemia therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

In vivo treatment of mutant FLT3-transformed murine leukemia with a tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Identification of a ligand for the c-kit proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Expression of the C-kit receptor (CD117) is a feature of almost all subtypes of de novo acute myeloblastic leukemia (AML), including cytogenetically good-risk AML, and lacks prognostic significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Classes of c-KIT activating mutations: proposed mechanisms of action and implications for disease classification and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Molecular basis for modulation of biological function by alternate splicing of the Wilms' tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Transactivation of an intronic hematopoietic-specific enhancer of the human Wilms' tumor 1 gene by GATA-1 and c-Myb

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Constitutive expression of the Wilms' tumor gene (WT1) in the leukemic cell line U937 blocks parts of the differentiation program

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

The Wilms tumour gene WT1 in leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Inhibition of cell proliferation by C/EBP alpha occurs in many cell types, does not require the presence of p53 or Rb, and is not affected by large T-antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

A 30-kDa alternative translation product of the CCAAT/enhancer binding protein alpha message: transcriptional activator lacking antimitotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

The t(8;21) fusion product, AML-1-ETO, associates with C/EBP-alpha, inhibits C/EBP-alpha-dependent transcription, and blocks granulocytic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

BCR-ABL suppresses C/EBPalpha expression through inhibitory action of hnRNP E2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Abnormalities of the CEBP alpha transcription factor: a major target in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Point mutations of the RUNx1/AML1 gene in sporadic and familial myeloid leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

A novel CBFA2 single-nucleotide mutation in familial platelet disorder with propensity to develop myeloid malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

Detection of CBFB/MYH11 transcripts in patients with inversion and other abnormalities of chromosome 16 at presentation and remission

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1468-0734.2002.00060.X

10.1046/J.1468-0734.2002.00060.X

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference