(Q34682178)

3 August 2017

title

Subcellular localization determines the stability and axon protective capacity of axon survival factor Nmnat2. (English)

1 reference

3 August 2017

Stefan Milde

1

1 reference

3 August 2017

Jonathan Gilley

series ordinal

2

1 reference

3 August 2017

Michael P Coleman

series ordinal

3

1 reference

3 August 2017

language of work or name

English

0 references

publication date

16 April 2013

1 reference

3 August 2017

1 reference

3 August 2017

volume

11

1 reference

3 August 2017

issue

4

1 reference

3 August 2017

page(s)

e1001539

1 reference

Creative Commons Attribution 4.0 International

3 August 2017

copyright license

start time

16 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3627647/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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A novel Drosophila model of nerve injury reveals an essential role of Nmnat in maintaining axonal integrity

7 July 2018

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7 July 2018

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CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy

7 July 2018

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Mechanistic logic underlying the axonal transport of cytosolic proteins

7 July 2018

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Making and breaking synapses through local mRNA regulation

7 July 2018

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7 July 2018

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BIM(EL), an intrinsically disordered protein, is degraded by 20S proteasomes in the absence of poly-ubiquitylation.

7 July 2018

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Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization

7 July 2018

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Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs.

7 July 2018

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Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: new insights on structure and function relationship

7 July 2018

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Expression, localization, and biochemical characterization of nicotinamide mononucleotide adenylyltransferase 2

7 July 2018

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7 July 2018

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Overexpression of Wld(S) or Nmnat2 in mauthner cells by single-cell electroporation delays axon degeneration in live zebrafish.

7 July 2018

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Size dependence of protein diffusion in the cytoplasm of Escherichia coli

7 July 2018

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Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases

7 July 2018

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Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Refining the minimal sequence required for ERK1/2-dependent poly-ubiquitination and proteasome-dependent turnover of BIM.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Nmnat2 delays axon degeneration in superior cervical ganglia dependent on its NAD synthesis activity.

7 July 2018

1 reference

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Palmitoylation of the synaptic vesicle fusion machinery.

7 July 2018

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Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration

7 July 2018

1 reference

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Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice

7 July 2018

1 reference

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Dynamic protein palmitoylation in cellular signaling

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Role of axonal transport in neurodegenerative diseases

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

NAD(+) and axon degeneration revisited: Nmnat1 cannot substitute for Wld(S) to delay Wallerian degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Visualization of retroviral replication in living cells reveals budding into multivesicular bodies.

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Involvement of the ubiquitin-proteasome system in the early stages of wallerian degeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

A photoactivatable GFP for selective photolabeling of proteins and cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Mass spectrometric analysis of GAP-43/neuromodulin reveals the presence of a variety of fatty acylated species

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Palmitoylation-dependent control of degradation, life span, and membrane expression of the CCR5 receptor.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Pathophysiological relevance of mitochondria in NAD(+) metabolism.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Palmitoylation of the recombinant human A1 adenosine receptor: enhanced proteolysis of palmitoylation-deficient mutant receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Analysis of the palmitoylation and membrane targeting domain of neuromodulin (GAP-43) by site-specific mutagenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

The gene for slow Wallerian degeneration (Wld(s)) is also protective against vincristine neuropathy.

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001539

WldS mice are resistant to paclitaxel (taxol) neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001539

The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001539

Wld(S) mice are protected against the Parkinsonian mimetic MPTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001539

Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001539

Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001539

Identification of process-localized mRNAs from cultured rodent hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001539

Nmnat2 protects cardiomyocytes from hypertrophy via activation of SIRT6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001539

Cell culture medium affects GFP photostability: a solution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001539

The Wlds mutation delays robust loss of motor and sensory axons in a genetic model for myelin-related axonopathy.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627647

Age-dependent axonal transport and locomotor changes and tau hypophosphorylation in a “P301L” tau knockin mouse

26 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001539

Inhibiting axon degeneration and synapse loss attenuates apoptosis and disease progression in a mouse model of motoneuron disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23610559

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intracellular sorting of neuromodulin (GAP-43) mutants modified in the membrane targeting domain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23610559

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PBIO.1001539

1 reference

3 August 2017

1 reference

3 August 2017

1 reference