(Q35747152)

English

CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy

scientific article published on 25 October 2011

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scholarly article

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15 January 2020

CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy (English)

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15 January 2020

1 reference

based on heuristic

inferred from title

neurodegeneration

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based on heuristic

inferred from title

4

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15 January 2020

author name string

M Cecilia Ljungberg

1

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Yousuf O Ali

2

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Jie Zhu

3

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Kazuhiro Oka

5

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R Grace Zhai

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Hui-Chen Lu

7

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publication date

25 October 2011

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Human Molecular Genetics

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21

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251-267

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describes a project that uses

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11 June 2022

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based on heuristic

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Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration

1 reference

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Axonal degeneration is blocked by nicotinamide mononucleotide adenylyltransferase (Nmnat) protein transduction into transected axons.

1 reference

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1 reference

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1 reference

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1 reference

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Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

1 reference

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1 reference

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Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress

1 reference

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1 reference

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Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity

1 reference

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The Drosophila cell corpse engulfment receptor Draper mediates glial clearance of severed axons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Ultrastructural neuronal pathology in transgenic mice expressing mutant (P301L) human tau.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Neuroprotection after transient global cerebral ischemia in Wld(s) mutant mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

P300 amplitude as a possible correlate of frontal degeneration in schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Tau protein pathology in neurodegenerative diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276285

25 September 2018

Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve

1 reference

https://pubmed.ncbi.nlm.nih.gov/22027994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP response element-binding protein (CREB) and CAAT/enhancer-binding protein beta (C/EBPbeta) bind chimeric DNA sites with high affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22027994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequency of tau gene mutations in familial and sporadic cases of non-Alzheimer dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22027994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FTDP-17: an early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22027994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDR492

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22027994%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22027994%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22027994%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

ResearchGate publication ID

0 references

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