(Q48128010)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20631169%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

beta-Amyloid disrupts activity-dependent gene transcription required for memory through the CREB coactivator CRTC1 (English)

1 reference

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7 February 2020

2

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7 February 2020

Alfredo Miñano-Molina

3

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7 February 2020

Roser Masgrau

4

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7 February 2020

José Rodríguez-Alvarez

9

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7 February 2020

Carlos A. Saura

10

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Cristina Guardia-Laguarta

7 February 2020

6

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7 February 2020

author name string

Judit España

1

1 reference

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7 February 2020

Elsa Martín

5

1 reference

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7 February 2020

Alberto Lleó

7

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7 February 2020

Lydia Giménez-Llort

8

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7 February 2020

language of work or name

English

0 references

publication date

1 July 2010

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7 February 2020

published in

Journal of Neuroscience

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7 February 2020

volume

30

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7 February 2020

issue

28

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7 February 2020

page(s)

9402-9410

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describes a project that uses

7 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6632424/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

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Selective changes of calcineurin (protein phosphatase 2B) activity in Alzheimer's disease cerebral cortex

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12 December 2020

Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised

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12 December 2020

Experience-dependent gene expression in the rat hippocampus after spatial learning: a comparison of the immediate-early genes Arc, c-fos, and zif268.

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Transcriptional regulation by the phosphorylation-dependent factor CREB

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12 December 2020

Calcium regulation of neuronal gene expression

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Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture

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12 December 2020

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Alzheimer's disease is a synaptic failure

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Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice.

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12 December 2020

Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

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12 December 2020

P-type calcium channels in rat central and peripheral neurons

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12 December 2020

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

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12 December 2020

Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells

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12 December 2020

TORCs: transducers of regulated CREB activity

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12 December 2020

Synaptic slaughter in Alzheimer's disease

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12 December 2020

Increased phosphorylation of the neuronal L-type Ca(2+) channel Ca(v)1.2 during aging

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12 December 2020

The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector

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12 December 2020

Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

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12 December 2020

Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins

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12 December 2020

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

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12 December 2020

Regulation of NMDA receptor trafficking by amyloid-beta

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12 December 2020

Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice.

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12 December 2020

Mapping behaviorally relevant neural circuits with immediate-early gene expression.

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12 December 2020

Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory

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12 December 2020

CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases

1 reference

12 December 2020

cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase

1 reference

12 December 2020

L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes

1 reference

12 December 2020

Differential effects of Ca2+ and cAMP on transcription mediated by MEF2D and cAMP-response element-binding protein in hippocampal neurons.

1 reference

12 December 2020

Ubiquitin hydrolase Uch-L1 rescues beta-amyloid-induced decreases in synaptic function and contextual memory

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12 December 2020

Modeling behavioral and neuronal symptoms of Alzheimer's disease in mice: a role for intraneuronal amyloid.

1 reference

12 December 2020

Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles

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12 December 2020

AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss

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12 December 2020

Requirement of TORC1 for late-phase long-term potentiation in the hippocampus

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12 December 2020

Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress.

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12 December 2020

Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells

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12 December 2020

TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity

1 reference

12 December 2020

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

1 reference

12 December 2020

Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression

1 reference

12 December 2020

Calcineurin activity is required for depolarization-induced, CREB-dependent gene transcription in cortical neurons.

1 reference

12 December 2020

Deregulation of NMDA-receptor function and down-stream signaling in APP[V717I] transgenic mice.

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12 December 2020

Evidence of Abeta- and transgene-dependent defects in ERK-CREB signaling in Alzheimer's models

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12 December 2020

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12 December 2020

Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.

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12 December 2020

Communication between the synapse and the nucleus in neuronal development, plasticity, and disease

1 reference

12 December 2020

The Creb1 coactivator Crtc1 is required for energy balance and fertility

1 reference

12 December 2020

Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease.

1 reference

12 December 2020

From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function

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12 December 2020

Gene expression changes in the course of normal brain aging are sexually dimorphic

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12 December 2020

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12 December 2020

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

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12 December 2020

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12 December 2020

TORC1 regulates activity-dependent CREB-target gene transcription and dendritic growth of developing cortical neurons.

1 reference

12 December 2020

Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects

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12 December 2020

Mild cholesterol depletion reduces amyloid-beta production by impairing APP trafficking to the cell surface

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12 December 2020

Physical and functional interaction between calcineurin and the cardiac L-type Ca2+ channel

1 reference

12 December 2020

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

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12 December 2020

Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice

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12 December 2020

Reversal of long-term dendritic spine alterations in Alzheimer disease models

1 reference

12 December 2020

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

1 reference

12 December 2020

Requirement for BDNF in activity-dependent survival of cortical neurons.

1 reference

12 December 2020

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein.

1 reference

12 December 2020

Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement

1 reference

12 December 2020

Phosphorylated CREB binds specifically to the nuclear protein CBP

1 reference

12 December 2020

CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression

1 reference

12 December 2020

TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300

1 reference

12 December 2020

10.1523/JNEUROSCI.2154-10.2010

Identifiers

DOI

1 reference

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7 February 2020

1 reference

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7 February 2020

1 reference