(Q40161957)

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Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells

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scholarly article

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Europe PubMed Central

18 September 2017

Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells (English)

1 reference

Europe PubMed Central

18 September 2017

1 reference

based on heuristic

inferred from title

Margaret Fahnestock

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672502&resulttype=core&format=json

16 May 2020

author name string

Diego J Garzon

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672502&resulttype=core&format=json

16 May 2020

language of work or name

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publication date

1 March 2007

1 reference

Europe PubMed Central

18 September 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672502&resulttype=core&format=json

16 May 2020

27

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672502&resulttype=core&format=json

16 May 2020

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672502&resulttype=core&format=json

16 May 2020

2628-2635

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672502&resulttype=core&format=json

16 May 2020

Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

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Toward a molecular biology of memory: the light's coming on!

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophins and synaptic plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of sodium dodecyl sulfate-stable amyloid beta-protein dimers in the hippocampus CA1 not exhibiting neurofibrillary tangle formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Region-Specific Neurotrophin Imbalances in Alzheimer Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in the nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased synaptic inhibition in dentate gyrus of mice with reduced levels of endogenous brain-derived neurotrophic factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human neuroblastomas with unfavorable biologies express high levels of brain-derived neurotrophic factor mRNA and a variety of its variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta -amyloid-(1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF dependence in neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta -peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new brain-derived neurotrophic factor transcript and decrease in brain-derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF and activity-dependent synaptic modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rat brain-derived neurotrophic factor-encoding gene generates multiple transcripts through alternative use of 5' exons and polyadenylation sites.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic slaughter in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro model of neurotoxicity of Abeta 1-42 and neuroprotection by a pentapeptide: irreversible events during the first hour

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human neuroblastoma cells in culture: a model for neuronal cell differentiation and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta/A4-evoked degeneration of differentiated SH-SY5Y human neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of brain-derived neurotrophic factor promoter regions mediating tissue-specific, axotomy-, and neuronal activity-induced expression in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain insults in rats induce increased expression of the BDNF gene through differential use of multiple promoters.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: a central role for amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential usage of multiple brain-derived neurotrophic factor promoters in the rat brain following neuronal activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived neurotrophic factor is reduced in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CREB and memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a signaling pathway involved in calcium regulation of BDNF expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities of neural circuitry in Alzheimer's disease: hippocampus and cortical cholinergic innervation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344400

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5053-06.2007

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672502&resulttype=core&format=json

16 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672502&resulttype=core&format=json

16 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672502&resulttype=core&format=json

16 May 2020

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