(Q40372287)

19 September 2017

Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L) (English)

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12 May 2020

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12

Karen H Ashe

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12 May 2020

author name string

Martin Ramsden

1

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12 May 2020

Linda Kotilinek

2

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12 May 2020

Colleen Forster

3

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12 May 2020

Jennifer Paulson

4

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12 May 2020

Eileen McGowan

5

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12 May 2020

Karen SantaCruz

6

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12 May 2020

Aaron Guimaraes

7

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12 May 2020

Mei Yue

8

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12 May 2020

Jada Lewis

9

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12 May 2020

George Carlson

10

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12 May 2020

Michael Hutton

11

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12 May 2020

language of work or name

English

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publication date

1 November 2005

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19 September 2017

Journal of Neuroscience

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12 May 2020

volume

25

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12 May 2020

page(s)

10637-10647

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12 May 2020

issue

46

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A protein factor essential for microtubule assembly

12 May 2020

cites work

1 reference

12 December 2020

Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein

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12 December 2020

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

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12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

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12 December 2020

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

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12 December 2020

Extended analysis of path data from mutant mice using the public domain software Wintrack

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12 December 2020

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

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12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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12 December 2020

Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease

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12 December 2020

Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

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12 December 2020

Inhibition of protein phosphatase 2A- and protein phosphatase 1-induced tau hyperphosphorylation and impairment of spatial memory retention in rats

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12 December 2020

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.

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12 December 2020

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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12 December 2020

Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles

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12 December 2020

Overactivation of glycogen synthase kinase-3 by inhibition of phosphoinositol-3 kinase and protein kinase C leads to hyperphosphorylation of tau and impairment of spatial memory.

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12 December 2020

Search strategies used by APP transgenic mice during navigation in the Morris water maze

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12 December 2020

Changed conformation of mutant Tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of Tau-4R/2N transgenic mice

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12 December 2020

Tau pathology in Alzheimer disease and other tauopathies

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12 December 2020

Bilateral injection of isoproterenol into hippocampus induces Alzheimer-like hyperphosphorylation of tau and spatial memory deficit in rat.

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12 December 2020

Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice

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12 December 2020

Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

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12 December 2020

Tau suppression in a neurodegenerative mouse model improves memory function

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12 December 2020

A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

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12 December 2020

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

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12 December 2020

Place navigation impaired in rats with hippocampal lesions

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12 December 2020

Control of memory formation through regulated expression of a CaMKII transgene

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12 December 2020

A vector for expressing foreign genes in the brains and hearts of transgenic mice

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12 December 2020

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

12 December 2020

Frontotemporal dementia and Parkinsonism linked to chromosome 17: a new group of tauopathies.

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12 December 2020

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

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12 December 2020

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

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12 December 2020

Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

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12 December 2020

Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly

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12 December 2020

Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

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12 December 2020

10.1523/JNEUROSCI.3279-05.2005

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725849&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6725849&resulttype=core&format=json

12 May 2020

1 reference