(Q44205872)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

title

Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

1 reference

Maria Grazia Spillantini

15

object named as

Maria Grazia Spillantini

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

14

Bernardino Ghetti

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

author name string

Bridget Allen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Esther Ingram

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Masaki Takao

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Michael J Smith

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Ross Jakes

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Kanwar Virdee

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Hirotaka Yoshida

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Max Holzer

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Molly Craxton

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Piers C Emson

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Cristiana Atzori

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Antonio Migheli

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

R Anthony Crowther

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

Michel Goedert

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

language of work or name

English

0 references

publication date

1 November 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

page(s)

9340-9351

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

Accelerated filament formation from tau protein with specific FTDP-17 missense mutations.

14 December 2019

cites work

1 reference

12 December 2020

p38 kinase is activated in the Alzheimer's disease brain

1 reference

12 December 2020

Tau pathology in a family with dementia and a P301L mutation in tau.

1 reference

12 December 2020

Assembly of paired helical filaments from mouse tau: implications for the neurofibrillary pathology in transgenic mouse models for Alzheimer's disease

1 reference

12 December 2020

Effects of frontotemporal dementia FTDP-17 mutations on heparin-induced assembly of tau filaments

1 reference

12 December 2020

Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau.

1 reference

12 December 2020

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

1 reference

12 December 2020

Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation

1 reference

12 December 2020

cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease.

1 reference

12 December 2020

FTDP-17: an early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation

1 reference

12 December 2020

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

1 reference

12 December 2020

Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein

1 reference

12 December 2020

Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein

1 reference

12 December 2020

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

1 reference

12 December 2020

Tau filament formation in transgenic mice expressing P301L tau.

1 reference

12 December 2020

A Japanese patient with frontotemporal dementia and parkinsonism by a tau P301S mutation

1 reference

12 December 2020

Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease

1 reference

12 December 2020

Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis

1 reference

12 December 2020

Tau gene mutation K257T causes a tauopathy similar to Pick's disease

1 reference

12 December 2020

Mammalian MAP kinase signalling cascades

1 reference

12 December 2020

Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear pa

1 reference

12 December 2020

The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase

1 reference

12 December 2020

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

1 reference

12 December 2020

Oligodendroglial tau filament formation in transgenic mice expressing G272V tau.

1 reference

12 December 2020

Neurodegenerative tauopathies

1 reference

12 December 2020

Gene expression profiling of the tau mutant (P301L) transgenic mouse brain

1 reference

12 December 2020

Pick's disease associated with the novel Tau gene mutation K369I.

1 reference

12 December 2020

A genomic sequence analysis of the mouse and human microtubule-associated protein tau.

1 reference

12 December 2020

The genetic and pathological classification of familial frontotemporal dementia

1 reference

12 December 2020

Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau.

1 reference

12 December 2020

FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain

1 reference

12 December 2020

Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau.

1 reference

12 December 2020

Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis.

1 reference

12 December 2020

Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in

1 reference

12 December 2020

Functional effects of tau gene mutations deltaN296 and N296H

1 reference

12 December 2020

Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

1 reference

12 December 2020

Protein kinases--the major drug targets of the twenty-first century?

1 reference

12 December 2020

p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]

1 reference

12 December 2020

Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state

1 reference

12 December 2020

Structure and novel exons of the human tau gene

1 reference

12 December 2020

Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms

1 reference

12 December 2020

Straight and paired helical filaments in Alzheimer disease have a common structural unit

1 reference

12 December 2020

Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization

1 reference

12 December 2020

A comparative study of modified Bielschowsky, Bodian and thioflavin S stains on Alzheimer's neurofibrillary tangles

1 reference

12 December 2020

Epitopes that span the tau molecule are shared with paired helical filaments.

1 reference

12 December 2020

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

1 reference

12 December 2020

Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain

1 reference

12 December 2020

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

1 reference

12 December 2020

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

12 December 2020

Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein

1 reference

12 December 2020

A study of apoptosis in normal and pathologic nervous tissue after in situ end-labeling of DNA strand breaks

1 reference

12 December 2020

Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404.

1 reference

12 December 2020

Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.

1 reference

12 December 2020

Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau

1 reference

12 December 2020

Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform

1 reference

12 December 2020

PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3 beta.

1 reference

12 December 2020

Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments

1 reference

12 December 2020

Characterization of mAb AP422, a novel phosphorylation-dependent monoclonal antibody against tau protein

1 reference

12 December 2020

AD2, a phosphorylation-dependent monoclonal antibody directed against tau proteins found in Alzheimer's disease

1 reference

12 December 2020

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans

1 reference

12 December 2020

The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

1 reference

12 December 2020

Stress-activated protein kinase/c-jun N-terminal kinase phosphorylates tau protein

1 reference

12 December 2020

Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments

1 reference

12 December 2020

Endogenous serine protease inhibitor modulates epileptic activity and hippocampal long-term potentiation

1 reference

12 December 2020

Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases

1 reference

12 December 2020

Diverse cell death pathways result from a single missense mutation in weaver mouse

1 reference

12 December 2020

Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation

1 reference

12 December 2020

Tau is a candidate gene for chromosome 17 frontotemporal dementia

1 reference

12 December 2020

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

1 reference

12 December 2020

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

1 reference

12 December 2020

Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau

1 reference

12 December 2020

Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly

1 reference

12 December 2020

Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

1 reference

12 December 2020

10.1523/JNEUROSCI.22-21-09340.2002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12417659%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

PubMed publication ID

12417659

1 reference