(Q34695691)

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Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 activation and IFN-beta expression: relevance to therapeutic effects in models of multiple sclerosis

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 activation and IFN-beta expression: relevance to therapeutic effects in models of multiple sclerosis (English)

1 reference

Europe PubMed Central

4 August 2017

multiple sclerosis

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object named as

Paul N Moynagh

6

1 reference

ORCID Public Data File 2021

3

object named as

Bruno Gran

1 reference

Europe PubMed Central

4 August 2017

author name string

Eric J Downer

1

1 reference

Europe PubMed Central

4 August 2017

Eileen Clifford

2

1 reference

Europe PubMed Central

4 August 2017

Hendrik J Nel

4

1 reference

Europe PubMed Central

4 August 2017

Padraic G Fallon

5

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Europe PubMed Central

4 August 2017

language of work or name

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publication date

18 January 2011

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Europe PubMed Central

4 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

4 August 2017

286

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Europe PubMed Central

4 August 2017

10316-10328

1 reference

Europe PubMed Central

4 August 2017

12

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Europe PubMed Central

4 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3060486/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060486

7 July 2018

Treatment of early multiple sclerosis: the value of treatment initiation after a first clinical episode

1 reference

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A role for galanin in human and experimental inflammatory demyelination

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The IKK-related kinases: from innate immunity to oncogenesis

1 reference

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Mechanisms of control of neuron survival by the endocannabinoid system

1 reference

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Adverse effects of medical cannabinoids: a systematic review

1 reference

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7 July 2018

Astrocytes in multiple sclerosis: a product of their environment

1 reference

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Role of the innate immune system in autoimmune inflammatory demyelination

1 reference

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7 July 2018

The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice

1 reference

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7 July 2018

The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.

1 reference

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Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors.

1 reference

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7 July 2018

Cannabinoids for the treatment of inflammation.

1 reference

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7 July 2018

The cannabinoid agonist WIN 55,212-2 inhibits TNF-alpha-induced neutrophil transmigration across ECV304 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060486

7 July 2018

Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis

1 reference

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7 July 2018

In silico patent searching reveals a new cannabinoid receptor

1 reference

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7 July 2018

Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity

1 reference

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7 July 2018

The synthetic cannabinoid R(+)WIN 55,212-2 inhibits the interleukin-1 signaling pathway in human astrocytes in a cannabinoid receptor-independent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060486

7 July 2018

TLR signalling and activation of IRFs: revisiting old friends from the NF-kappaB pathway

1 reference

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7 July 2018

Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060486

7 July 2018

Cannabinoids and neuroinflammation

1 reference

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7 July 2018

Immunoregulation of a viral model of multiple sclerosis using the synthetic cannabinoid R+WIN55,212

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060486

7 July 2018

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

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7 July 2018

TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060486

7 July 2018

Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA.

1 reference

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7 July 2018

Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family

1 reference

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IRF family of transcription factors as regulators of host defense

1 reference

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7 July 2018

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

1 reference

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7 July 2018

Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG)

1 reference

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7 July 2018

Molecular characterization of a peripheral receptor for cannabinoids

1 reference

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7 July 2018

Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

1 reference

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7 July 2018

Delta 9-tetrahydrocannabinol: a novel treatment for experimental autoimmune encephalomyelitis

1 reference

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7 July 2018

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

1 reference

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7 July 2018

Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188599

21 January 2018

Effect of sublingual application of cannabinoids on intraocular pressure: a pilot study.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188599

21 January 2018

Broad expression of Toll-like receptors in the human central nervous system

1 reference

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21 January 2018

Lipopolysaccharide pretreatment modulates the disease course in experimental autoimmune encephalomyelitis.

1 reference

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21 January 2018

A novel anti-inflammatory role of NCAM-derived mimetic peptide, FGL.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188599

21 January 2018

Impaired maturation and altered regulatory function of plasmacytoid dendritic cells in multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188599

21 January 2018

Interferon-beta stabilizes barrier characteristics of the blood-brain barrier in four different species in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188599

21 January 2018

The anti-inflammatory activities of cannabinoid receptor ligands in mouse peritonitis models

1 reference

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21 January 2018

Win 55212-2, a cannabinoid receptor agonist, attenuates leukocyte/endothelial interactions in an experimental autoimmune encephalomyelitis model.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188599

21 January 2018

TLR3-mediated IFN-β gene induction is negatively regulated by the TLR adaptor MyD88 adaptor-like

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188599

21 January 2018

Cannabinoids ablate release of TNFalpha in rat microglial cells stimulated with lypopolysaccharide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188599

21 January 2018

Effect of the cannabinoid receptor ligand, WIN 55,212-2, on superoxide anion and TNF-alpha production by human mononuclear cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188599

21 January 2018

Evidences of cannabinoids-induced modulation of paroxysmal events in an experimental model of partial epilepsy in the rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.188599

21 January 2018

Effects of cannabinoid receptor agonist and antagonist ligands on production of inflammatory cytokines and anti-inflammatory interleukin-10 in endotoxemic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diminished production of type-I interferons and interleukin-2 in patients with multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Magnetic resonance imaging results of the PRISMS trial: a randomized, double-blind, placebo-controlled study of interferon-beta1a in relapsing-remitting multiple sclerosis. Prevention of Relapses and Disability by Interferon-beta1a Subcutaneously in

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting Edge: TLR3 stimulation suppresses experimental autoimmune encephalomyelitis by inducing endogenous IFN-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epstein-Barr virus and multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21245146

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.188599

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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