(Q34713167)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

title

Uric acid promotes apoptosis in human proximal tubule cells by oxidative stress and the activation of NADPH oxidase NOX 4 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

0 references

1 reference

1

1 reference

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25 February 2020

Giacomo Garibotto

6

1 reference

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25 February 2020

author name string

Elena Ratto

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Barbara Villaggio

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Emanuele Luigi Parodi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Roberto Pontremoli

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Francesca Viazzi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

language of work or name

English

0 references

publication date

16 December 2014

1 reference

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25 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

issue

12

1 reference

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25 February 2020

page(s)

e115210

1 reference

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Creative Commons Attribution 4.0 International

25 February 2020

copyright license

start time

16 December 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Effects of uric acid-lowering therapy on renal outcomes: a systematic review and meta-analysis

1 reference

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Uric acid and chronic kidney disease: which is chasing which?

7 July 2018

1 reference

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Determinants of kidney oxygen consumption and their relationship to tissue oxygen tension in diabetes and hypertension.

7 July 2018

1 reference

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Febuxostat suppressed renal ischemia-reperfusion injury via reduced oxidative stress

7 July 2018

1 reference

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Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Serum uric acid levels and incident chronic kidney disease in patients with type 2 diabetes and preserved kidney function.

7 July 2018

1 reference

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IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Apoptosis and acute kidney injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Renal tubulointerstitial hypoxia: cause and consequence of kidney dysfunction.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Differentially expressed protein profile of renal tubule cell stimulated by elevated uric acid using SILAC coupled to LC-MS.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Myofibroblast differentiation during fibrosis: role of NAD(P)H oxidases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

NAD(P)H oxidase and renal epithelial ion transport

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

New paradigms in cell death in human diabetic nephropathy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Serum uric acid levels predict the development of albuminuria over 6 years in patients with type 1 diabetes: findings from the Coronary Artery Calcification in Type 1 Diabetes study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Elevated uric acid increases the risk for kidney disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Uricosuric action of losartan via the inhibition of urate transporter 1 (URAT 1) in hypertensive patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Uric acid: the oxidant-antioxidant paradox

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Uric acid and incident kidney disease in the community

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Treatment with the xanthine oxidase inhibitor febuxostat lowers uric acid and alleviates systemic and glomerular hypertension in experimental hyperuricaemia.

7 July 2018

1 reference

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Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

NADPH oxidases in the kidney

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Serum uric acid: a risk factor and a target for treatment?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Targeting XIAP for the treatment of malignancy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Uric acid as a mediator of endothelial dysfunction, inflammation, and vascular disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

The multispecific organic anion transporter family: properties and pharmacological significance

7 July 2018

1 reference

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Angiotensin II-induced mesangial cell apoptosis: role of oxidative stress.

7 July 2018

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IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

7 July 2018

1 reference

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Significance of hyperuricemia on the early detection of renal failure in a cohort of screened subjects

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

Mild hyperuricemia and subclinical renal damage in untreated primary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

Uric acid causes vascular smooth muscle cell proliferation by entering cells via a functional urate transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

Mild hyperuricemia induces vasoconstriction and maintains glomerular hypertension in normal and remnant kidney rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

ICE/CED3-like proteases as therapeutic targets for the control of inappropriate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type 2 diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

High molecular weight plasma proteins induce apoptosis and Fas/FasL expression in human proximal tubular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

The impact of serum uric acid on cardiovascular outcomes in the LIFE study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

Hydroxylated estrogen metabolites influence the proliferation of cultured human monocytes: possible role in synovial tissue hyperplasia.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4267812

Uric acid-induced endothelial dysfunction is associated with mitochondrial alterations and decreased intracellular ATP concentrations

26 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0115210

Advanced oxidation protein products: a causative link between oxidative stress and podocyte depletion

21 January 2018

1 reference

12 December 2020

An initial reduction in serum uric acid during angiotensin receptor blocker treatment is associated with cardiovascular protection: a post-hoc analysis of the RENAAL and IDNT trials

1 reference

12 December 2020

Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of endpoints in non-insulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial

1 reference

12 December 2020

Uric acid and serum antioxidant capacity: a reaction to atherosclerosis?

1 reference

12 December 2020

Hypertriglyceridaemia and hyperuricaemia are risk factors for progression of IgA nephropathy

1 reference

12 December 2020

Nephrology forum: apoptotic regulatory proteins in renal injury

1 reference

12 December 2020

Serum uric acid and renal prognosis in patients with IgA nephropathy

1 reference

12 December 2020

Apoptosis of tubular epithelial cells in familial juvenile gouty nephropathy

1 reference

12 December 2020

Uric acid inhibits renal proximal tubule cell proliferation via at least two signaling pathways involving PKC, MAPK, cPLA2, and NF-κB

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0115210

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

PubMed publication ID

25514209

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25514209%20AND%20SRC:MED&resulttype=core&format=json