(Q34714061)

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Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3.

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Europe PubMed Central

PubMed publication ID

4 August 2017

Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3. (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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reactive oxygen species

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based on heuristic

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author name string

Weijie Gao

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Fenglian Xiao

2

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Xiaoping Wang

3

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Tongsheng Chen

4

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Europe PubMed Central

PubMed publication ID

4 August 2017

publication date

1 October 2013

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Europe PubMed Central

PubMed publication ID

4 August 2017

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Europe PubMed Central

PubMed publication ID

4 August 2017

18

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Europe PubMed Central

PubMed publication ID

4 August 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

1201-1213

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Artesunate induces ROS-mediated apoptosis in doxorubicin-resistant T leukemia cells

1 reference

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21 January 2018

Artemisinin selectively decreases functional levels of estrogen receptor-alpha and ablates estrogen-induced proliferation in human breast cancer cells

1 reference

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21 January 2018

Artemisinin blocks prostate cancer growth and cell cycle progression by disrupting Sp1 interactions with the cyclin-dependent kinase-4 (CDK4) promoter and inhibiting CDK4 gene expression.

1 reference

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Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells

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Dihydroartemisinin Induces Apoptosis by a Bak-Dependent Intrinsic Pathway

1 reference

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21 January 2018

The role of heme and the mitochondrion in the chemical and molecular mechanisms of mammalian cell death induced by the artemisinin antimalarials

1 reference

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21 January 2018

Experimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of Action

1 reference

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21 January 2018

Single-cell analysis of dihydroartemisinin–induced apoptosis through reactive oxygen species–mediated caspase-8 activation and mitochondrial pathway in ASTC-a-1 cells using fluorescence imaging techniques

1 reference

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21 January 2018

The JNK inhibitor SP600125 enhances dihydroartemisinin-induced apoptosis by accelerating Bax translocation into mitochondria in human lung adenocarcinoma cells

1 reference

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21 January 2018

Amplification activation loop between caspase-8 and -9 dominates artemisinin-induced apoptosis of ASTC-a-1 cells

1 reference

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21 January 2018

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

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21 January 2018

Mitochondrial activation of apoptosis

1 reference

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21 January 2018

Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death

1 reference

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21 January 2018

Cleavage of Bid by executioner caspases mediates feed forward amplification of mitochondrial outer membrane permeabilization during genotoxic stress-induced apoptosis in Jurkat cells

1 reference

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21 January 2018

Sulfur mustard induces apoptosis in lung epithelial cells via a caspase amplification loop

1 reference

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21 January 2018

Fas/CD95-mediated apoptosis of type II cells is blocked by Toxoplasma gondii primarily via interference with the mitochondrial amplification loop

1 reference

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21 January 2018

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

1 reference

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21 January 2018

TNF-alpha induces two distinct caspase-8 activation pathways

1 reference

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21 January 2018

Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.

1 reference

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21 January 2018

Etoposide induces protein kinase Cdelta- and caspase-3-dependent apoptosis in neuroblastoma cancer cells

1 reference

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21 January 2018

Autocrine amplification loop in statin-induced apoptosis of human melanoma cells.

1 reference

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21 January 2018

Resveratrol induces apoptosis via a Bak-mediated intrinsic pathway in human lung adenocarcinoma cells

1 reference

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21 January 2018

Bid is not required for Bax translocation during UV-induced apoptosis

1 reference

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21 January 2018

Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation.

1 reference

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21 January 2018

Dihydroartemisinin induces apoptosis and sensitizes human ovarian cancer cells to carboplatin therapy

1 reference

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21 January 2018

The role of calcium, P38 MAPK in dihydroartemisinin-induced apoptosis of lung cancer PC-14 cells.

1 reference

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21 January 2018

Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells.

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21 January 2018

Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines

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21 January 2018

Artesunate activates mitochondrial apoptosis in breast cancer cells via iron-catalyzed lysosomal reactive oxygen species production

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21 January 2018

Artesunate induces apoptosis via a Bak-mediated caspase-independent intrinsic pathway in human lung adenocarcinoma cells

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21 January 2018

Effects of artemisinin and its derivatives on growth inhibition and apoptosis of oral cancer cells.

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21 January 2018

Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis

1 reference

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21 January 2018

Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction

1 reference

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21 January 2018

Lysosomal membrane permeabilization in cell death

1 reference

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21 January 2018

Evidence for the Involvement of Carbon-centered Radicals in the Induction of Apoptotic Cell Death by Artemisinin Compounds

1 reference

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21 January 2018

Identifiers

10.1007/S10495-013-0857-Z

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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