(Q34715639)

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Mutant Escherichia coli heat-labile toxin B subunit that separates toxoid-mediated signaling and immunomodulatory action from trafficking and delivery functions

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Mutant Escherichia coli heat-labile toxin B subunit that separates toxoid-mediated signaling and immunomodulatory action from trafficking and delivery functions (English)

1 reference

Europe PubMed Central

4 August 2017

Escherichia coli

1 reference

based on heuristic

inferred from title

5

object named as

Robert J Salmond

1 reference

Europe PubMed Central

4 August 2017

author name string

Sylvia A Fraser

1

1 reference

Europe PubMed Central

4 August 2017

Lolke de Haan

2

1 reference

Europe PubMed Central

4 August 2017

Arron R Hearn

3

1 reference

Europe PubMed Central

4 August 2017

Heather K Bone

4

1 reference

Europe PubMed Central

4 August 2017

A Jennifer Rivett

6

1 reference

Europe PubMed Central

4 August 2017

Neil A Williams

7

1 reference

Europe PubMed Central

4 August 2017

Timothy R Hirst

8

1 reference

Europe PubMed Central

4 August 2017

language of work or name

0 references

publication date

1 March 2003

1 reference

Europe PubMed Central

4 August 2017

Infection and Immunity

1 reference

Europe PubMed Central

4 August 2017

71

1 reference

Europe PubMed Central

4 August 2017

1527-1537

1 reference

Europe PubMed Central

4 August 2017

3

1 reference

Europe PubMed Central

4 August 2017

Modulation of human monocytes by Escherichia coli heat-labile enterotoxin B-subunit; altered cytokine production and its functional consequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

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Enhanced delivery of exogenous peptides into the class I antigen processing and presentation pathway

1 reference

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7 July 2018

Contribution of the ADP-ribosylating and receptor-binding properties of cholera-like enterotoxins in modulating cytokine secretion by human intestinal epithelial cells

1 reference

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7 July 2018

A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity

1 reference

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7 July 2018

Escherichia coli enterotoxin B subunit triggers apoptosis of CD8(+) T cells by activating transcription factor c-myc

1 reference

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7 July 2018

Cholera toxin and Escherichia coli enterotoxin B-subunits inhibit macrophage-mediated antigen processing and presentation: evidence for antigen persistence in non-acidic recycling endosomal compartments

1 reference

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7 July 2018

Escherichia coli heat-labile enterotoxin B subunit is a more potent mucosal adjuvant than its vlosely related homologue, the B subunit of cholera toxin

1 reference

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7 July 2018

Protective mucosal immunity to ocular herpes simplex virus type 1 infection in mice by using Escherichia coli heat-labile enterotoxin B subunit as an adjuvant.

1 reference

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Cholera toxin and related enterotoxins: a cell biological and immunological perspective.

1 reference

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The role of CD4 and CD8 T cells in recovery and protection from retroviral infection: lessons from the Friend virus model

1 reference

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7 July 2018

Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins

1 reference

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Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor

1 reference

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7 July 2018

Membrane traffic and the cellular uptake of cholera toxin

1 reference

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7 July 2018

Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic

1 reference

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7 July 2018

Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor beta1 and beta2 chain expression

1 reference

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7 July 2018

Ganglioside structure dictates signal transduction by cholera toxin and association with caveolae-like membrane domains in polarized epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Glycosphingolipids as novel targets for T-cell suppression by the B subunit of recombinant heat-labile enterotoxin

1 reference

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7 July 2018

Modulation of B-cell activation by the B subunit of Escherichia coli enterotoxin: receptor interaction up-regulates MHC class II, B7, CD40, CD25 and ICAM-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Prevention of autoimmune disease due to lymphocyte modulation by the B-subunit of Escherichia coli heat-labile enterotoxin

1 reference

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A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes

1 reference

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7 July 2018

Quantitative analysis of bacterial toxin affinity and specificity for glycolipid receptors by surface plasmon resonance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

A pH-dependent conformational change in the B-subunit pentamer of Escherichia coli heat-labile enterotoxin: structural basis and possible functional role for a conserved feature of the AB5 toxin family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Treatment of experimental autoimmune encephalomyelitis by feeding myelin basic protein conjugated to cholera toxin B subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Cross-linking of cell surface ganglioside GM1 induces the selective apoptosis of mature CD8+ T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Distinct effects of recombinant cholera toxin B subunit and holotoxin on different stages of class II MHC antigen processing and presentation by macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Potent immunogenicity of the B subunits of Escherichia coli heat-labile enterotoxin: receptor binding is essential and induces differential modulation of lymphocyte subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Purification of the B-subunit oligomer of Escherichia coli heat-labile enterotoxin by heterologous expression and secretion in a marine vibrio.

1 reference

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7 July 2018

Galactose-binding site in Escherichia coli heat-labile enterotoxin (LT) and cholera toxin (CT)

1 reference

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7 July 2018

The heat-labile enterotoxin of Escherichia coli binds to polylactosaminoglycan-containing receptors in CaCo-2 human intestinal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Comparison of the glycolipid-binding specificities of cholera toxin and porcine Escherichia coli heat-labile enterotoxin: identification of a receptor-active non-ganglioside glycolipid for the heat-labile toxin in infant rabbit small intestine.

1 reference

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7 July 2018

Rabbit intestinal glycoprotein receptor for Escherichia coli heat-labile enterotoxin lacking affinity for cholera toxin.

1 reference

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7 July 2018

Mechanism of action of cholera toxin: Effect of receptor density and multivalent binding on activation of adenylate cyclase

1 reference

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Lectin-binding sites as markers of Golgi subcompartments: proximal-to-distal maturation of oligosaccharides

1 reference

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Comparison of the carbohydrate-binding specificities of cholera toxin and Escherichia coli heat-labile enterotoxins LTh-I, LT-IIa, and LT-IIb

1 reference

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1 reference

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Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Inhibition of murine lymphocyte proliferation by the B subunit of cholera toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Generation of class I MHC-restricted T-T hybridomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Cholera toxin stimulates IL-1 production and enhances antigen presentation by macrophages in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

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Neoglycolipid analogs of ganglioside GM1 as functional receptors of cholera toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

7 July 2018

Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

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A homologue of the Escherichia coli DsbA protein involved in disulphide bond formation is required for enterotoxin biogenesis in Vibrio cholerae

1 reference

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Characterization of EBV-genome negative “null” and “T” cell lines derived from children with acute lymphoblastic leukemia and leukemic transformed non-Hodgkin lymphoma

1 reference

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7 July 2018

CD8+ T cell apoptosis induced by Escherichia coli heat-labile enterotoxin B subunit occurs via a novel pathway involving NF-kappaB-dependent caspase activation.

1 reference

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Antigen-receptor cross-linking and lipopolysaccharide trigger distinct phosphoinositide 3-kinase-dependent pathways to NF-kappa B activation in primary B cells

1 reference

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Mucosal immunoadjuvant activity of recombinant Escherichia coli heat-labile enterotoxin and its B subunit: induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with influenza virus surface antigen

1 reference

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26 October 2018

Induction of mucosal and systemic immune responses by intranasal immunization using recombinant cholera toxin B subunit as an adjuvant.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

26 October 2018

Recombinant cholera toxin B subunit acts as an adjuvant for the mucosal and systemic responses of mice to mucosally co-administered bovine serum albumin.

1 reference

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Cholera toxin binding affinity and specificity for gangliosides determined by surface plasmon resonance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=148879

26 October 2018

Kinetics of acid-mediated disassembly of the B subunit pentamer of Escherichia coli heat-labile enterotoxin. Molecular basis of pH stability.

1 reference

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26 October 2018

A Cholera Toxin B-subunit Variant That Binds Ganglioside GM1but Fails to Induce Toxicity

1 reference

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Modulation of B lymphocyte signalling by the B subunit of Escherichia coli heat-labile enterotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595472

12 December 2020

based on heuristic

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Action of Vibrio cholerae neuraminidase (sialidase) upon the surface of intact cells and their isolated sialolipid components

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595472

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based on heuristic

inferred from PubMed ID database lookup

Tryptophan residues of cholera toxin and its A and B protomers. Intrinsic fluorescence and solute quenching upon interacting with the ganglioside GM1, oligo-GM1, or dansylated oligo-GM1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular basis of immunomodulation by cholera toxin in vitro with possible association to the adjuvant function in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP-independent effects of cholera toxin on B cell activation. II. Binding of ganglioside GM1 induces B cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential induction of programmed cell death in CD8+ and CD4+ T cells by the B subunit of cholera toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of GM1 binding in the mucosal immunogenicity and adjuvant activity of the Escherichia coli heat-labile enterotoxin and its B subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/12595472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.71.3.1527-1537.2003

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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