(Q34720232)

English

Serotonin transporter interacts with the PDGFβ receptor in PDGF-BB-induced signaling and mitogenesis in pulmonary artery smooth muscle cells

scientific article

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Serotonin transporter interacts with the PDGFβ receptor in PDGF-BB-induced signaling and mitogenesis in pulmonary artery smooth muscle cells (English)

1 reference

Europe PubMed Central

4 August 2017

0 references

author name string

Wenying Ren

1

1 reference

Europe PubMed Central

4 August 2017

Stephanie W Watts

2

1 reference

Europe PubMed Central

4 August 2017

Barry L Fanburg

3

1 reference

Europe PubMed Central

4 August 2017

publication date

24 December 2010

1 reference

Europe PubMed Central

4 August 2017

American Journal of Physiology - Lung Cellular and Molecular Physiology

1 reference

Europe PubMed Central

4 August 2017

300

1 reference

Europe PubMed Central

4 August 2017

3

1 reference

Europe PubMed Central

4 August 2017

L486-97

1 reference

Europe PubMed Central

4 August 2017

Evaluation of imatinib mesylate in the treatment of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Regulation of platelet-derived growth factor receptor function by integrin-associated cell surface transglutaminase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Growth factors outside of the platelet-derived growth factor (PDGF) family employ reactive oxygen species/Src family kinases to activate PDGF receptor alpha and thereby promote proliferation and survival of cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Pulmonary hypertension: therapeutic targets within the serotonin system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Role of platelet-derived growth factors in physiology and medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Platelet-derived growth factor expression and function in idiopathic pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

The G protein G alpha(13) is required for growth factor-induced cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Reversal of experimental pulmonary hypertension by PDGF inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Serotonin-induced growth of pulmonary artery smooth muscle requires activation of phosphatidylinositol 3-kinase/serine-threonine protein kinase B/mammalian target of rapamycin/p70 ribosomal S6 kinase 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

A role for platelet-derived growth factor beta-receptor in a newborn rat model of endothelin-mediated pulmonary vascular remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Treatment of pulmonary arterial hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

PDGF signaling in cells and mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Attenuated hypoxic pulmonary hypertension in mice lacking the 5-hydroxytryptamine transporter gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Serotonin stimulates mitogen-activated protein kinase activity through the formation of superoxide anion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Signal transduction via platelet-derived growth factor receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Signaling through scaffold, anchoring, and adaptor proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Dimerization of cell surface receptors in signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Cloning and expression of a functional serotonin transporter from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064292

7 July 2018

Imatinib for the treatment of pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Characterization of the serotonin transporter knockout rat: a selective change in the functioning of the serotonergic system.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

The 5-HT transporter transactivates the PDGFbeta receptor in pulmonary artery smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Overexpression of the 5-hydroxytryptamine transporter gene: effect on pulmonary hemodynamics and hypoxia-induced pulmonary hypertension.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Differential effect of simvastatin on various signal transduction intermediates in cultured human smooth muscle cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Significant improvement of right ventricular function by imatinib mesylate in scleroderma-associated pulmonary arterial hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Serotonin (5-HT) transport in human platelets is modulated by Src-catalysed Tyr-phosphorylation of the plasma membrane transporter SERT.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Continuous fluoxetine administration prevents recurrence of pulmonary arterial hypertension and prolongs survival in rats.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Imatinib Mesylate in the Treatment of Refractory Idiopathic Pulmonary Arterial Hypertension

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00237.2010

21 January 2018

Role of platelet-derived growth factor in vascular remodeling during pulmonary hypertension in the ovine fetus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21186266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual effect of serotonin on growth of bovine pulmonary artery smooth muscle cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/21186266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/21186266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of Tyr phosphorylation of GTPase-activating protein with mitogenic action of serotonin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21186266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide as an intermediate signal for serotonin-induced mitogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21186266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21186266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of imatinib on PDGF-induced proliferation and PDGF receptor signaling in human arterial and venous smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21186266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPLUNG.00237.2010

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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