(Q34725251)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078428%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

review article

1 reference

title

The preclinical properties of a novel group II metabotropic glutamate receptor agonist LY379268 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078428%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Gabor Imre

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078428%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

publication date

1 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078428%20AND%20SRC:MED&resulttype=core&format=json

CNS Neuroscience & Therapeutics

29 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078428%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078428%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078428%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

444-464

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078428%20AND%20SRC:MED&resulttype=core&format=json

Serotonin, via 5-HT2A receptors, increases EPSCs in layer V pyramidal cells of prefrontal cortex by an asynchronous mode of glutamate release

29 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Suppression of alcohol self-administration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)-3,4-DCPG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Comparison of the effect of glutamate receptor modulators in the 6 Hz and maximal electroshock seizure models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Protective role of group-II metabotropic glutamate receptors against nigro-striatal degeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

LY379268, a potent and selective Group II metabotropic glutamate receptor agonist, is neuroprotective in gerbil global, but not focal, cerebral ischaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

The novel mGluR2/3 agonist LY379268 attenuates cue-induced reinstatement of heroin seeking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

The mGluR2/3 agonist LY379268 attenuates context- and discrete cue-induced reinstatement of sucrose seeking but not sucrose self-administration in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Protection of neonatal rat brain from hypoxic-ischemic injury by LY379268, a Group II metabotropic glutamate receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Regulation of neurotransmitter release by metabotropic glutamate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Dopamine and 5-HT turnover are increased by the mGlu2/3 receptor agonist LY379268 in rat medial prefrontal cortex, nucleus accumbens and striatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Acute increases in monoamine release in the rat prefrontal cortex by the mGlu2/3 agonist LY379268 are similar in profile to risperidone, not locally mediated, and can be elicited in the presence of uptake blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Pharmacology and functions of metabotropic glutamate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Expression of glutamate uptake transporters after dibutyryl cyclic AMP differentiation and traumatic injury in cultured astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Glutamate receptors and nociception: implications for the drug treatment of pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Analgesic effects of the selective group II (mGlu2/3) metabotropic glutamate receptor agonists LY379268 and LY389795 in persistent and inflammatory pain models after acute and repeated dosing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Activity-dependent presynaptic autoinhibition by group II metabotropic glutamate receptors at the perforant path inputs to the dentate gyrus and CA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

The mGlu2/3 receptor agonist LY379268 blocks the expression of locomotor sensitization by amphetamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Activation of group II mGlu receptors blocks the enhanced drug taking induced by previous exposure to amphetamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Neuroprotection by metabotropic glutamate receptor glutamate receptor agonists: LY354740, LY379268 and LY389795.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Effects of the selective metabotropic glutamate agonist LY354740 in a rat model of permanent ischaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Cloning, distribution and functional expression of the human mGlu6 metabotropic glutamate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Changes in subcellular localization of metabotropic glutamate receptor subtypes during postnatal development of mouse thalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Effects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: modulation by a group II selective metabotropic glutamate receptor agonist LY379268.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Group II mGlu receptor activation suppresses norepinephrine release in the ventral hippocampus and locomotor responses to acute ketamine challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Diagnosis, Prevention and Treatment of Aspirin-Induced Asthma and Rhinitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Imipramine treatment up-regulates the expression and function of mGlu2/3 metabotropic glutamate receptors in the rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Metabotropic glutamate receptors 2 and 3 expressed by astrocytes in rat ventrobasal thalamus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Anti-epileptic activity of group II metabotropic glutamate receptor agonists (--)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268) and (--)-2-thia-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY389795).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Astrocyte mGlu(2/3)-mediated cAMP potentiation is calcium sensitive: studies in murine neuronal and astrocyte cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Design, synthesis, and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY354740): a potent, selective, and orally active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxioly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Evaluation of the mGluR2/3 agonist LY379268 in rodent models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Distribution of a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat and mouse: an immunohistochemical study with a monoclonal antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

The group II metabotropic glutamate receptor agonist, LY379268, inhibits both cocaine- and food-seeking behavior in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

The metabotropic glutamate receptors, mGluR2 and mGluR3, show unique postsynaptic, presynaptic and glial localizations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Striatal metabotropic glutamate receptor function following experimental parkinsonism and chronic levodopa treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Effects of memantine, an NMDA receptor antagonist, on place preference conditioned with drug and nondrug reinforcers in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Endogenous activation of group-II metabotropic glutamate receptors inhibits the hypothalamic-pituitary-adrenocortical axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

The metabotropic glutamate receptor 5 antagonist MPEP and the mGluR2 agonist LY379268 modify disease progression in a transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Pharmacological agents acting at subtypes of metabotropic glutamate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Systemic pre-treatment with a group II mGlu agonist, LY379268, reduces hyperalgesia in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Insight into the function of Group I and Group II metabotropic glutamate (mGlu) receptors: behavioural characterization and implications for the treatment of CNS disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Metabotropic glutamate receptors as novel targets for anxiety and stress disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

Group II metabotropic glutamate receptor modulation of DOI-induced c-fos mRNA and excitatory responses in the cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00024.X

The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats

21 January 2018

1 reference

12 December 2020

Selective activation of group II mGluRs with LY354740 does not prevent neuronal excitotoxicity

1 reference

12 December 2020

Group II selective metabotropic glutamate receptor agonists and local cerebral glucose use in the rat

1 reference

12 December 2020

Physiological antagonism between 5-hydroxytryptamine(2A) and group II metabotropic glutamate receptors in prefrontal cortex

1 reference

12 December 2020

Tolerance to the motor impairment, but not to the reversal of PCP-induced motor activities by oral administration of the mGlu2/3 receptor agonist, LY379268

1 reference

12 December 2020

Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors

1 reference

12 December 2020

Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine

1 reference

12 December 2020

The potent, selective mGlu2/3 receptor agonist LY379268 increases extracellular levels of dopamine, 3,4-dihydroxyphenylacetic acid, homovanillic acid, and 5-hydroxyindole-3-acetic acid in the medial prefrontal cortex of the freely moving rat

1 reference

12 December 2020

Neuroprotective effects of LY379268, a selective mGlu2/3 receptor agonist: investigations into possible mechanism of action in vivo

1 reference

12 December 2020

l-glutamate as a central neurotransmitter: looking back

1 reference

12 December 2020

The mGlu(2/3) receptor agonist LY379268 selectively blocks amphetamine ambulations and rearing

1 reference

12 December 2020

Memantine and ACPC affect conditioned place preference induced by cocaine in rats.

1 reference

12 December 2020

Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells.

1 reference

12 December 2020

Time-dependent reversal of long-term potentiation by low-frequency stimulation at the hippocampal mossy fiber-CA3 synapses.

1 reference

12 December 2020

Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system

1 reference

12 December 2020

Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity.

1 reference

12 December 2020

Group II mGlu receptor agonists inhibit behavioural and electrophysiological effects of DOI in mice

1 reference

12 December 2020

Effects of the mGlu2/3 receptor agonist LY379268 on motor activity in phencyclidine-sensitized rats

1 reference

12 December 2020

Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats

1 reference

12 December 2020

Modulation of stress-induced and stimulated hyperprolactinemia with the group II metabotropic glutamate receptor selective agonist, LY379268.

1 reference

12 December 2020

The group II metabotropic glutamate receptor agonist (-)-2-oxa-4-aminobicyclo[3.1.0.]hexane-4,6-dicarboxylate (LY379268) and clozapine reverse phencyclidine-induced behaviors in monoamine-depleted rats

1 reference

12 December 2020

Direct and indirect modulation of the N-methyl D-aspartate receptor

1 reference

12 December 2020

Toluene-induced locomotor activity is blocked by 6-hydroxydopamine lesions of the nucleus accumbens and the mGluR2/3 agonist LY379268.

1 reference

12 December 2020

Group II metabotropic glutamate receptors regulate the vulnerability to hypoxic brain damage.

1 reference

12 December 2020

Serotonergic/glutamatergic interactions: the effects of mGlu 2/3 receptor ligands in rats trained with LSD and PCP as discriminative stimuli

1 reference

12 December 2020

Selective action of (-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268), a group II metabotropic glutamate receptor agonist, on basal and phencyclidine-induced dopamine release in the nucleus accumbens shell

1 reference

12 December 2020

The mGlu2/3 receptor agonist LY379268 injected into cortex or thalamus decreases neuronal injury in retrosplenial cortex produced by NMDA receptor antagonist MK-801: possible implications for psychosis

1 reference

12 December 2020

Dopamine is not required for the hyperlocomotor response to NMDA receptor antagonists

1 reference

12 December 2020

Comparison of the effects of diazepam, the CRF1 antagonist CP-154,526 and the group II mGlu receptor agonist LY379268 on stress-evoked extracellular norepinephrine levels

1 reference

12 December 2020

Metabotropic glutamate receptors and neuroadaptation to antidepressants: imipramine-induced down-regulation of beta-adrenergic receptors in mice treated with metabotropic glutamate 2/3 receptor ligands.

1 reference

12 December 2020

The preferential mGlu2/3 receptor antagonist, LY341495, reduces the frequency of spike-wave discharges in the WAG/Rij rat model of absence epilepsy

1 reference

12 December 2020

A selective allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors has effects similar to an orthosteric mGlu2/3 receptor agonist in mouse models predictive of antipsychotic activity

1 reference

12 December 2020

Effects of the mGluR2/3 agonist LY379268 on ketamine-evoked behaviours and neurochemical changes in the dentate gyrus of the rat.

1 reference

12 December 2020

Distribution of the mRNA for a metabotropic glutamate receptor (mGluR3) in the rat brain: an in situ hybridization study

1 reference

12 December 2020

Modulation of glial cell signaling by adenosine and pharmacological reinforcement. A neuroprotective strategy?

1 reference

12 December 2020

Roles of metabotropic glutamate receptors in glial function and glial-neuronal communication

1 reference

12 December 2020

The neuroprotective activity of group-II metabotropic glutamate receptors requires new protein synthesis and involves a glial-neuronal signaling

1 reference

12 December 2020

Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex.

1 reference

12 December 2020

mGluR II agonist inhibition of LTP induction, and mGluR II antagonist inhibition of LTD induction, in the dentate gyrus in vitro.

1 reference

12 December 2020

The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception

1 reference

12 December 2020

Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus

1 reference

12 December 2020

Regulation of the glial Na+-dependent glutamate transporters by cyclic AMP analogs and neurons

1 reference

12 December 2020

Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta

1 reference

12 December 2020

AMPA receptors and motivation for drug: effect of the selective antagonist NBQX on behavioural sensitization and on self-administration in mice.

1 reference

12 December 2020

Metabotropic glutamate receptors: electrophysiological properties and role in plasticity

1 reference

12 December 2020

10.1111/J.1527-3458.2007.00024.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078428%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18078428%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference