(Q34727532)

4 August 2017

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title

Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis (English)

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4 August 2017

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6

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4 August 2017

2

Mark A Smith

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4 August 2017

1

Miguel A Pappolla

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4 August 2017

3

Tara Bryant-Thomas

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4 August 2017

9

Lorenzo M Refolo

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4 August 2017

8

Mary Sano

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4 August 2017

Nicolas Bazan

4

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4 August 2017

Suzana Petanceska

series ordinal

5

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4 August 2017

Leon J Thal

series ordinal

7

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4 August 2017

publication date

1 July 2002

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Free Radical Biology and Medicine

4 August 2017

published in

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4 August 2017

volume

33

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4 August 2017

issue

2

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4 August 2017

page(s)

173-181

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

4 August 2017

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Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

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7 January 2021

The molecular and cellular biology of tau.

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Alzheimer beta protein mediated oxidative damage of mitochondrial DNA: prevention by melatonin

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7 January 2021

Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease

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7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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7 January 2021

Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides

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7 January 2021

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

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7 January 2021

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

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Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

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Regulation of APP cleavage by alpha-, beta- and gamma-secretases

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7 January 2021

Abeta-generating enzymes: recent advances in beta- and gamma-secretase research

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7 January 2021

In search of gamma-secretase: presenilin at the cutting edge

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7 January 2021

Fibrillogenesis of synthetic amyloid-beta peptides is dependent on their initial secondary structure

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7 January 2021

Oxidative processes in Alzheimer's disease: the role of abeta-metal interactions

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7 January 2021

Solution Structures of β Peptide and Its Constituent Fragments: Relation to Amyloid Deposition

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7 January 2021

Structural and kinetic features of amyloid beta-protein fibrillogenesis

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7 January 2021

Alzheimer's disease: a re-examination of the amyloid hypothesis

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7 January 2021

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

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7 January 2021

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

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7 January 2021

A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease

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7 January 2021

Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol

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7 January 2021

Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

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7 January 2021

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

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7 January 2021

The role of cholesterol in the biosynthesis of beta-amyloid

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7 January 2021

Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease

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7 January 2021

Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study

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7 January 2021

Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: a population-based study of African Americans

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7 January 2021

Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study

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7 January 2021

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

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7 January 2021

Statins and the risk of dementia

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7 January 2021

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

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7 January 2021

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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7 January 2021

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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7 January 2021

Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion

1 reference

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7 January 2021

Preamyloid deposits in the cerebral cortex of patients with Alzheimer's disease and nondemented individuals.

1 reference

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7 January 2021

Heat-shock induces abnormalities in the cellular distribution of amyloid precursor protein (APP) and APP fusion proteins

1 reference

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7 January 2021

Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide.

1 reference

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7 January 2021

Processing of Alzheimer's amyloid precursor protein during H2O2-induced apoptosis in human neuronal cells

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7 January 2021

Oxygen free radicals and hypercholesterolemic atherosclerosis: effect of vitamin E

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7 January 2021

Reduction of Serum Cholesterol and Hypercholesterolemic Atherosclerosis in Rabbits by Secoisolariciresinol Diglucoside Isolated From Flaxseed

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7 January 2021

Membrane microdomains and caveolae

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7 January 2021

Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta

1 reference

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7 January 2021

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

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7 January 2021

Early contribution of oxidative glycation in Alzheimer disease

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7 January 2021

4-hydroxy-2-nonenal pyrrole adducts in human neurodegenerative disease.

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7 January 2021

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

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7 January 2021

Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress

1 reference

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7 January 2021

Autopsy samples of Alzheimer's cortex show increased peroxidation in vitro

1 reference

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7 January 2021

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

1 reference

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7 January 2021

Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

1 reference

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7 January 2021

D1-dopamine receptor abnormality in frontal cortex points to a functional alteration of cortical cell membranes in Alzheimer's disease.

1 reference

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7 January 2021

Cerebrovascular hypoperfusion: a risk factor for Alzheimer's disease? Animal model and postmortem human studies

1 reference

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7 January 2021

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Free radical damage, iron, and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Oxidative stress hypothesis in Alzheimer's disease

1 reference

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7 January 2021

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

1 reference

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7 January 2021

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Excitatory amino acids, growth factors, and calcium: a teeter-totter model for neural plasticity and degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

The superoxide-generating oxidase of phagocytic cells. Physiological, molecular and pathological aspects

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Pathological implications of nitric oxide, superoxide and peroxynitrite formation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Widespread peroxynitrite-mediated damage in Alzheimer's disease.

1 reference

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7 January 2021

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

1 reference

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7 January 2021

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

1 reference

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7 January 2021

Heat shock proteins protect against stress-related phosphorylation of tau in neuronal PC12 cells that have acquired thermotolerance

1 reference

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7 January 2021

In vitro polymerization of oxidized tau into filaments.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Two new genes for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

The gene defects responsible for familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Concentration-dependent inhibitory effects of apolipoprotein E on Alzheimer's beta-amyloid fibril formation in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

Opposite roles of apolipoprotein E in normal brains and in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900841-9

7 January 2021

10.1016/S0891-5849(02)00841-9

Identifiers

DOI

1 reference

4 August 2017

1 reference