(Q34729793)

4 August 2017

A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer (English)

1 reference

4 August 2017

1 reference

Ignacio Varela

20

0 references

Chang-Lung Lee

object named as

Chang-Lung Lee

15

0 references

Angelika Schnieke

object named as

Angelika E Schnieke

23

0 references

David Kirsch

17

object named as

David G Kirsch

1 reference

4 August 2017

24

Hans-Reimer Rodewald

1 reference

4 August 2017

Nina Schönhuber

1

1 reference

4 August 2017

Barbara Seidler

2

1 reference

4 August 2017

Kathleen Schuck

3

1 reference

4 August 2017

Christian Veltkamp

4

1 reference

4 August 2017

Christina Schachtler

5

1 reference

4 August 2017

Magdalena Zukowska

6

1 reference

4 August 2017

Stefan Eser

7

1 reference

4 August 2017

Thorsten B Feyerabend

8

1 reference

4 August 2017

Mariel C Paul

9

1 reference

4 August 2017

Philipp Eser

10

1 reference

4 August 2017

Sabine Klein

11

1 reference

4 August 2017

Andrew M Lowy

12

1 reference

4 August 2017

Ruby Banerjee

13

1 reference

4 August 2017

Fangtang Yang

14

1 reference

4 August 2017

Everett J Moding

16

1 reference

4 August 2017

Angelika Scheideler

18

1 reference

4 August 2017

Dario R Alessi

19

1 reference

4 August 2017

Allan Bradley

21

1 reference

4 August 2017

Alexander Kind

22

1 reference

4 August 2017

Roland Rad

25

1 reference

4 August 2017

Roland M Schmid

26

1 reference

4 August 2017

Günter Schneider

27

1 reference

4 August 2017

Dieter Saur

28

1 reference

4 August 2017

language of work or name

English

0 references

publication date

19 October 2014

1 reference

4 August 2017

1 reference

4 August 2017

20

1 reference

4 August 2017

11

1 reference

4 August 2017

1340-1347

1 reference

https://scigraph.springernature.com/pub.10.1038/nm.3646

4 August 2017

0 references

cites work

A modular and flexible ESC-based mouse model of pancreatic cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Efemp1 and p27(Kip1) modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

7 July 2018

Cancer statistics, 2013

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Generation of primary tumors with Flp recombinase in FRT-flanked p53 mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

RAS oncogenes: weaving a tumorigenic web

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Mast cells in tumor microenvironment promotes the in vivo growth of pancreatic ductal adenocarcinoma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Genetically engineered mouse models of pancreatic cancer: unravelling tumour biology and progressing translational oncology.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

A conditional knockout resource for the genome-wide study of mouse gene function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Uncoupling cancer mutations reveals critical timing of p53 loss in sarcomagenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Context-dependent transformation of adult pancreatic cells by oncogenic K-Ras

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

A Cre-loxP-based mouse model for conditional somatic gene expression and knockdown in vivo by using avian retroviral vectors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

A global double-fluorescent Cre reporter mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Vagaries of conditional gene targeting

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Pathology of genetically engineered mouse models of pancreatic exocrine cancer: consensus report and recommendations.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

CXCR4 expression increases liver and lung metastasis in a mouse model of pancreatic cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Mast cells: the Jekyll and Hyde of tumor growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Single-nucleotide promoter polymorphism alters transcription of neuronal nitric oxide synthase exon 1c in infantile hypertrophic pyloric stenosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Essential role of PDK1 in regulating cell size and development in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Independent prognostic value of eosinophil and mast cell infiltration in colorectal cancer tissue

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4270133

Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer

7 July 2018

1 reference

Mast cells and pancreatic cancer

21 January 2018

1 reference

Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors

21 January 2018

1 reference

Interstitial cells of Cajal integrate excitatory and inhibitory neurotransmission with intestinal slow-wave activity

21 January 2018

1 reference

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

21 January 2018

1 reference

An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus.

21 January 2018

1 reference

A porcine model of familial adenomatous polyposis

21 January 2018

1 reference

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25326799

12 December 2020

inferred from PubMed ID database lookup

Chronic Pancreatitis Is Essential for Induction of Pancreatic Ductal Adenocarcinoma by K-Ras Oncogenes in Adult Mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25326799

12 December 2020

inferred from PubMed ID database lookup

Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25326799

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NM.3646

1 reference

release_oky2u7skx5eonf5tanwhnerfuu

4 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/oky2u7skx5eonf5tanwhnerfuu

24 November 2022

mapped directly with Wikidata item

PMCID

4270133

1 reference

4 August 2017

1 reference