(Q34729967)

4 August 2017

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title

DNA polymerase zeta (pol zeta) in higher eukaryotes (English)

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4 August 2017

4

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4 August 2017

2

John P Wittschieben

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PubMed ID

18157155

4 August 2017

Birgitte Ø Wittschieben

series ordinal

3

object named as

Birgitte Ø Wittschieben

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4 August 2017

Gregory N Gan

1

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4 August 2017

1 January 2008

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4 August 2017

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4 August 2017

18

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4 August 2017

174-183

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4 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/cr.2007.117

4 August 2017

0 references

cites work

Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Cellular roles of DNA polymerase zeta and Rev1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

UV-induced reversion of his4 frameshift mutations in rad6, rev1, and rev3 mutants of yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Thymine-thymine dimer bypass by yeast DNA polymerase zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Transcription-associated mutagenesis in yeast is directly proportional to the level of gene expression and influenced by the direction of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

The relative roles in vivo of Saccharomyces cerevisiae Pol eta, Pol zeta, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cis-syn cyclobutane dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Deoxycytidyl transferase activity of yeast REV1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

ATR homolog Mec1 controls association of DNA polymerase zeta-Rev1 complex with regions near a double-strand break

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Complex formation with Rev1 enhances the proficiency of Saccharomyces cerevisiae DNA polymerase zeta for mismatch extension and for extension opposite from DNA lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Proliferating cell nuclear antigen promotes translesion synthesis by DNA polymerase zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

The 9-1-1 checkpoint clamp physically interacts with polzeta and is partially required for spontaneous polzeta-dependent mutagenesis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

A ubiquitin-binding motif in the translesion DNA polymerase Rev1 mediates its essential functional interaction with ubiquitinated proliferating cell nuclear antigen in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

A full-length cDNA of hREV3 is predicted to encode DNA polymerase zeta for damage-induced mutagenesis in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Alternative splicing, genomic structure, and fine chromosome localization of REV3L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Identification, chromosomal mapping and tissue-specific expression of hREV3 encoding a putative human DNA polymerase zeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Molecular cloning, expression and chromosomal localisation of the mouse Rev3l gene, encoding the catalytic subunit of polymerase zeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Functional analysis of p53 binding under differential stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Response of REV3 promoter to N-methyl-N'-nitro-N-nitrosoguanidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Molecular characterization of seizure-related genes isolated by differential screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

The property of DNA polymerase zeta: REV7 is a putative protein involved in translesion DNA synthesis and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

The human REV1 gene codes for a DNA template-dependent dCMP transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

A human REV7 homolog that interacts with the polymerase zeta catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Structure and enzymatic properties of a stable complex of the human REV1 and REV7 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Mouse Rev1 protein interacts with multiple DNA polymerases involved in translesion DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Biochemical properties of the human REV1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Deoxycytidyl transferase activity of the human REV1 protein is closely associated with the conserved polymerase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Roles of the polymerase and BRCT domains of Rev1 protein in translesion DNA synthesis in yeast in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Vertebrate DNA damage tolerance requires the C-terminus but not BRCT or transferase domains of REV1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

The BRCT domain of mammalian Rev1 is involved in regulating DNA translesion synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Co-localization in replication foci and interaction of human Y-family members, DNA polymerase pol eta and REVl protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

REV1 protein interacts with PCNA: significance of the REV1 BRCT domain in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Analyses of ultraviolet-induced focus formation of hREV1 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

The catalytic activity of REV1 is employed during immunoglobulin gene diversification in DT40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Characterization of MAD2B and other mitotic spindle checkpoint genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Rev7/MAD2B links c-Jun N-terminal protein kinase pathway signaling to activation of the transcription factor Elk-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

MAD2B is an inhibitor of the anaphase-promoting complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

A bacterial effector targets Mad2L2, an APC inhibitor, to modulate host cell cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Inactivation of human MAD2B in nasopharyngeal carcinoma cells leads to chemosensitization to DNA-damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

hREV3 is essential for error-prone translesion synthesis past UV or benzo[a]pyrene diol epoxide-induced DNA lesions in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

The function of the human homolog of Saccharomyces cerevisiae REV1 is required for mutagenesis induced by UV light

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

DNA polymerase zeta regulates cisplatin cytotoxicity, mutagenicity, and the rate of development of cisplatin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

DNA polymerase zeta accounts for the reduced cytotoxicity and enhanced mutagenicity of cisplatin in human colon carcinoma cells that have lost DNA mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Suppression of hREV1 expression reduces the rate at which human ovarian carcinoma cells acquire resistance to cisplatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Human REV1 modulates the cytotoxicity and mutagenicity of cisplatin in human ovarian carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Multiple roles of Rev3, the catalytic subunit of polzeta in maintaining genome stability in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Multiple roles of vertebrate REV genes in DNA repair and recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen (PCNA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Involvement of nucleotide excision repair in a recombination-independent and error-prone pathway of DNA interstrand cross-link repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

The pso mutants of Saccharomyces cerevisiae comprise two groups: one deficient in DNA repair and another with altered mutagen metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

DNA interstrand cross-link repair in the cell cycle: a critical role for polymerase zeta in G1 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Disruption of the developmentally regulated Rev3l gene causes embryonic lethality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Disruption of the Rev3l-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Sez4 gene encoding an elongation subunit of DNA polymerase zeta is required for normal embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Immortalized mouse cell lines that lack a functional Rev3 gene are hypersensitive to UV irradiation and cisplatin treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Isolation and genetic characterisation of the Drosophila homologue of (SCE)REV3, encoding the catalytic subunit of DNA polymerase zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Purification of Drosophila DNA polymerase zeta by REV1 protein-affinity chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Drosophila DNA polymerase zeta interacts with recombination repair protein 1, the Drosophila homologue of human abasic endonuclease 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Cloning and characterization of Rrp1, the gene encoding Drosophila strand transferase: carboxy-terminal homology to DNA repair endo/exonucleases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Drosophila Rrp1 protein: an apurinic endonuclease with homologous recombination activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Disruption of the AtREV3 gene causes hypersensitivity to ultraviolet B light and gamma-rays in Arabidopsis: implication of the presence of a translesion synthesis mechanism in plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Tolerance of dividing cells to replication stress in UVB-irradiated Arabidopsis roots: requirements for DNA translesion polymerases eta and zeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Roles of Arabidopsis AtREV1 and AtREV7 in translesion synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Decreased Frequency of Somatic Hypermutation and Impaired Affinity Maturation but Intact Germinal Center Formation in Mice Expressing Antisense RNA to DNA Polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

Mutagenesis in eukaryotes dependent on DNA polymerase zeta and Rev1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

7 January 2021

Pathways of ultraviolet mutability in Saccharomyces cerevisiae. I. Some properties of double mutants involving uvs9 and rev

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

7 January 2021

REV7, a new gene concerned with UV mutagenesis in yeast

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

7 January 2021

REV3, a Saccharomyces cerevisiae gene whose function is required for induced mutagenesis, is predicted to encode a nonessential DNA polymerase

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

7 January 2021

The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

7 January 2021

DNA polymerase zeta introduces multiple mutations when bypassing spontaneous DNA damage in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

7 January 2021

Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA.

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

7 January 2021

An essential role for REV3 in mammalian cell survival: absence of REV3 induces p53-independent embryonic death

1 reference

https://api.crossref.org/works/10.1038%2FCR.2007.117

7 January 2021

Identifiers

DOI

10.1038/CR.2007.117

1 reference

4 August 2017

1 reference

PubMed ID

18157155