(Q34737067)

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Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24973094%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24973094%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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Ronald N. Hines

6

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21 March 2020

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Swetha Rudraiah

1

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21 March 2020

Philip R Rohrer

2

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21 March 2020

Igor Gurevich

3

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21 March 2020

Michael J Goedken

4

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21 March 2020

Theodore Rasmussen

5

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21 March 2020

José E Manautou

7

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21 March 2020

publication date

27 June 2014

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21 March 2020

Toxicological Sciences

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21 March 2020

141

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21 March 2020

1

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21 March 2020

263-277

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21 March 2020

Analysis of changes in hepatic gene expression in a murine model of tolerance to acetaminophen hepatotoxicity (autoprotection).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Current issues with acetaminophen hepatotoxicity--a clinically relevant model to test the efficacy of natural products

1 reference

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7 July 2018

The potential of knockout mouse lines in defining the role of flavin-containing monooxygenases in drug metabolism

1 reference

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7 July 2018

Flavin-containing monooxygenase-3: induction by 3-methylcholanthrene and complex regulation by xenobiotic chemicals in hepatoma cells and mouse liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Mechanisms of acetaminophen-induced liver necrosis

1 reference

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7 July 2018

Deletion of the mouse Fmo1 gene results in enhanced pharmacological behavioural responses to imipramine

1 reference

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7 July 2018

A high-efficiency system for the generation and study of human induced pluripotent stem cells

1 reference

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7 July 2018

Aryl hydrocarbon receptor-dependent induction of flavin-containing monooxygenase mRNAs in mouse liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Acquired resistance to acetaminophen hepatotoxicity is associated with induction of multidrug resistance-associated protein 4 (Mrp4) in proliferating hepatocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Molecular and functional characterization of drug-metabolizing enzymes and transporter expression in the novel spontaneously immortalized human hepatocyte line HC-04.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Differential gene expression in mouse liver associated with the hepatoprotective effect of clofibrate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Developmental and tissue-specific expression of human flavin-containing monooxygenases 1 and 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Human flavin-containing monooxygenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Intracellular signaling mechanisms of acetaminophen-induced liver cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Cytochrome P450 2C8 and flavin-containing monooxygenases are involved in the metabolism of tazarotenic acid in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Interindividual differences of human flavin-containing monooxygenase 3: genetic polymorphisms and functional variation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Repeat exposure to incremental doses of acetaminophen provides protection against acetaminophen-induced lethality in mice: an explanation for high acetaminophen dosage in humans without hepatic injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Physiological factors affecting protein expression of flavin-containing monooxygenases 1, 3 and 5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Effect of methimazole, an FMO substrate and competitive inhibitor, on the neurotoxicity of 3,3'-iminodipropionitrile in male rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Selective protein covalent binding and target organ toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Characterization of flavin-containing monooxygenase 5 (FMO5) cloned from human and guinea pig: evidence that the unique catalytic properties of FMO5 are not confined to the rabbit ortholog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Methimazole-associated cholestatic liver injury: case report and brief literature review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Role of hepatocellular regeneration in CCl4 autoprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

7 July 2018

Studies on the Nature and Regulation of the Cellular Thiol:Disulphide Potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271123

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Inhibition of hepatic mixed-function oxidase activity in vitro and in vivo by various thiono-sulfur-containing compounds

1 reference

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7 July 2018

Acetaminophen metabolism does not contribute to gender difference in its hepatotoxicity in mouse.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU124

21 January 2018

Molecular cloning, sequencing, and expression in Escherichia coli of mouse flavin-containing monooxygenase 3 (FMO3): comparison with the human isoform

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU124

21 January 2018

Cell-, tissue-, sex- and developmental stage-specific expression of mouse flavin-containing monooxygenases (Fmos).

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU124

21 January 2018

Mechanisms for the cytotoxicity of cysteamine

1 reference

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The Case for Limiting Acetaminophen-Related Deaths: Smaller Doses and Unbundling the Opioid–Acetaminophen Compounds

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU124

21 January 2018

Clofibrate pretreatment diminishes acetaminophen's selective covalent binding and hepatotoxicity.

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU124

21 January 2018

Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU124

21 January 2018

Cholestasis induced by model organic anions protects from acetaminophen hepatotoxicity in male CD-1 mice

1 reference

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21 January 2018

Role of yeast flavin-containing monooxygenase in maintenance of thiol-disulfide redox potential

1 reference

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21 January 2018

Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU124

21 January 2018

Microsomal oxidation of thiobenzamide. A photometric assay for the flavin-containing monooxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism-dependent hepatotoxicity of methimazole in mice depleted of glutathione

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of sulfhydryl groups in biology and medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional activity of the mouse flavin-containing monooxygenase forms 1, 3, and 5

1 reference

https://pubmed.ncbi.nlm.nih.gov/24973094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/TOXSCI/KFU124

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24973094%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24973094%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24973094%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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