(Q34737266)

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Molecular properties of HLA-DQ alleles conferring susceptibility to or protection from insulin-dependent diabetes mellitus: keys to the fate of islet beta-cells

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Europe PubMed Central

PubMed publication ID

4 August 2017

1 reference

Europe PubMed Central

Molecular properties of HLA-DQ alleles conferring susceptibility to or protection from insulin-dependent diabetes mellitus: keys to the fate of islet beta-cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

1 reference

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George K. Papadopoulos

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George K Papadopoulos

2

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author name string

Antonis K Moustakas

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

publication date

1 May 2002

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

American Journal of Medical Genetics Part A

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Europe PubMed Central

PubMed publication ID

4 August 2017

115

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Europe PubMed Central

PubMed publication ID

4 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

37-47

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Type 1 diabetes-predisposing MHC alleles influence the selection of glutamic acid decarboxylase (GAD) 65-specific T cells in a transgenic model.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

High affinity presentation of an autoantigenic peptide in type I diabetes by an HLA class II protein encoded in a haplotype protecting from disease.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Dendritic cells and the control of immunity

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Allelic variation in transcription modulates MHC class II expression and function.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Endosomal proteolysis and MHC class II function

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Association of susceptibility to spontaneous diabetes in rat with genes of major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Autoreactive and immunoregulatory T-cell subsets in insulin-dependent diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Crystal structure of I-Ak in complex with a dominant epitope of lysozyme

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

High precursor frequency of human T cells reactive to HLA-DQ molecules expressed on mouse L cell transfectants

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Use of eluted peptide sequence data to identify the binding characteristics of peptides to the insulin-dependent diabetes susceptibility allele HLA-DQ8 (DQ 3.2).

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Evidence for a long prediabetic period in type I (insulin-dependent) diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Peripheral tolerance as a multi-step mechanism

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

How the immune system works to protect the host from infection: a personal view

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Preferential presentation of herpes simplex virus T-cell antigen by HLA DQA1*0501/DQB1*0201 in comparison to HLA DQA1*0201/DQB1*0201.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Involvement of both major histocompatibility complex class II alpha and beta chains in CD4 function indicates a role for ordered oligomerization in T cell activation

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

HLA-DQB1 codon 57 is critical for peptide binding and recognition.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

HLA-DQ tetramers identify epitope-specific T cells in peripheral blood of herpes simplex virus type 2-infected individuals: direct detection of immunodominant antigen-responsive cells

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Irreversible association of peptides with class II MHC molecules in living cells.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Monocytes are differentially activated through HLA-DR, -DQ, and -DP molecules via mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Complete sequence and gene map of a human major histocompatibility complex. The MHC sequencing consortium

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Mechanisms of tolerance to self

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

A unified hypothesis for the complex genetics of HLA associations with IDDM.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Molecular basis for HLA-DQ associations with IDDM.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

SYFPEITHI: database for MHC ligands and peptide motifs

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

T-cell responses to autoantigens in IDDM. The search for the Holy Grail

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Immunological suppression by human CD8+ T cells is receptor dependent and HLA-DQ restricted

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Polymorphic amino acid variations in HLA-DQ are associated with systematic physical property changes and occurrence of IDDM. Members of the Swedish Childhood Diabetes Study

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Crystal structures of two I-Ad-peptide complexes reveal that high affinity can be achieved without large anchor residues

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Molecular basis of celiac disease

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

HLA and disease associations: detecting the strongest association

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to type 1 (insulin-dependent) diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

DRB1*0403 protects against IDDM in Caucasians with the high-risk heterozygous DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 genotype. Belgian Diabetes Registry

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

The peptide binding motif of the disease associated HLA-DQ (alpha 1* 0501, beta 1* 0201) molecule

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Genetic control of autoimmune diabetes in the NOD mouse

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

HLA-DQ is epistatic to HLA-DR in controlling the immune response to schistosomal antigen in humans

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Prevention of autoimmune insulitis by expression of I–E molecules in NOD mice

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Prevention of diabetes in non-obese diabetic I-Ak transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FAJMG.10342

21 January 2018

Identifiers

10.1002/AJMG.10342

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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