(Q34746605)

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Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

Robert J. Desnick

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Robert J Desnick

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

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Lisa Edelmann

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2 January 2020

Ruth Kornreich

3

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Europe PubMed Central

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2 January 2020

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17 January 2008

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2 January 2020

American Journal of Human Genetics

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

82

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

495-500

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

CYP2C9, CYP2C19 and CYP2D6 allele frequencies in the Ashkenazi Jewish population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

7 July 2018

Warfarin dose and the pharmacogenomics of CYP2C9 and VKORC1 - rationale and perspectives

1 reference

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Pharmacogenetics-based coumarin therapy

1 reference

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7 July 2018

Appraisal of current vitamin K dosing algorithms for the reversal of over-anticoagulation with warfarin: the need for a more tailored dosing regimen

1 reference

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Pharmacogenetics of warfarin: current status and future challenges

1 reference

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7 July 2018

Genetic influences on the response to warfarin

1 reference

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7 July 2018

The human cytochrome P450 Allele Nomenclature Committee Web site: submission criteria, procedures, and objectives

1 reference

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7 July 2018

The c.-1639G > A polymorphism of the VKORC1 gene is a major determinant of the response to acenocoumarol in anticoagulated patients

1 reference

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7 July 2018

Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose

1 reference

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7 July 2018

A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

7 July 2018

Clinical consequences of cytochrome P450 2C9 polymorphisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

7 July 2018

Vitamin K epoxide reductase: homology, active site and catalytic mechanism

1 reference

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7 July 2018

The risk of bleeding complications in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon

1 reference

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7 July 2018

Racial and ethnic differences in warfarin response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

7 July 2018

Identification of the gene for vitamin K epoxide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

7 July 2018

Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

7 July 2018

Clinical relevance of genetic polymorphisms in the human CYP2C9 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

7 July 2018

CYP2C9 allelic variants: ethnic distribution and functional significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

7 July 2018

Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

7 July 2018

Genotypes of the cytochrome p450 isoform, CYP2C9, and the vitamin K epoxide reductase complex subunit 1 conjointly determine stable warfarin dose: a prospective study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

26 October 2018

A warfarin-dosing model in Asians that uses single-nucleotide polymorphisms in vitamin K epoxide reductase complex and cytochrome P450 2C9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

26 October 2018

Influence of coagulation factor, vitamin K epoxide reductase complex subunit 1, and cytochrome P450 2C9 gene polymorphisms on warfarin dose requirements.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

26 October 2018

A vitamin K epoxide reductase complex subunit-1 (VKORC1) mutation in a patient with vitamin K antagonist resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

26 October 2018

The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

26 October 2018

Pharmacodynamic resistance to warfarin associated with a Val66Met substitution in vitamin K epoxide reductase complex subunit 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

26 October 2018

A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2427171

26 October 2018

Racial background is a determinant factor in the maintenance dosage of warfarin.

1 reference

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26 October 2018

Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy

1 reference

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26 October 2018

VKORCI haplotypes and their impact on the inter-individual and inter-ethnical variability of oral anticoagulation

1 reference

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9 December 2018

Main haplotypes and mutational analysis of vitamin K epoxide reductase (VKORC1) in a Swedish population: a retrospective analysis of case records

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new vitamin K epoxide reductase complex subunit-1 (VKORC1) mutation in a patient with decreased stability of CYP2C9 enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estimation of warfarin maintenance dose based on VKORC1 (-1639 G>A) and CYP2C9 genotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18252229

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.AJHG.2007.10.002

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18252229%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

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