(Q34750573)

4 August 2017

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title

Beta-amyloid (Abeta) protein in cerebrospinal fluid as a biomarker for Alzheimer's disease (English)

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4 August 2017

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2

Kaj Blennow

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4 August 2017

Niels Andreasen

1

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4 August 2017

publication date

1 July 2002

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4 August 2017

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4 August 2017

volume

23

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4 August 2017

issue

7

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4 August 2017

page(s)

1205-1214

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Unusual phenotypic alteration of beta amyloid precursor protein (betaAPP) maturation by a new Val-715 --> Met betaAPP-770 mutation responsible for probable early-onset Alzheimer's disease

4 August 2017

cites work

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7 January 2021

Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease.

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7 January 2021

Cerebrospinal fluid tau and Abeta42 as predictors of development of Alzheimer's disease in patients with mild cognitive impairment

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7 January 2021

Evaluation of CSF-tau and CSF-Abeta42 as diagnostic markers for Alzheimer disease in clinical practice

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7 January 2021

Serpents on the road to dementia and death. Accumulating evidence from several studies points to the normal function of presenilin 1 and suggests how the mutant protein contributes to deposition of amyloid plaques in Alzheimer's disease.

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7 January 2021

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

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7 January 2021

Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene

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7 January 2021

Consensus Report of the Working Group on: “Molecular and Biochemical Markers of Alzheimer’s Disease” 11The names of the Working Group Members and the names of the Working Group Advisory Committee Members are listed in the Appendix A(section VI)

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7 January 2021

A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques.

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7 January 2021

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

1 reference

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7 January 2021

A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43)

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Low cerebrospinal-fluid concentrations of soluble amyloid beta-protein precursor in hereditary Alzheimer's disease

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7 January 2021

Clinical-neuropathological correlations in Alzheimer's disease and related dementias

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7 January 2021

High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Amyloid beta-peptide is produced by cultured cells during normal metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

1 reference

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7 January 2021

Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

1 reference

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7 January 2021

Cerebrospinal fluid markers for Alzheimer's disease evaluated after acute ischemic stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease.

1 reference

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7 January 2021

Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Diagnostic accuracy of Alzheimer's disease: a clinicopathological study.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Cerebrospinal fluid A beta42 is increased early in sporadic Alzheimer's disease and declines with disease progression

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Longitudinal study of cerebrospinal fluid levels of tau, A beta1-40, and A beta1-42(43) in Alzheimer's disease: a study in Japan.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Decreased CSF amyloid beta42 and normal tau levels in dementia with Lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Diagnostic accuracy of Alzheimer's disease: a neuropathological study.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

The effects of age, apolipoprotein E phenotype and gender on the concentration of amyloid-beta (A beta) 40, A beta 4242, apolipoprotein E and transthyretin in human cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Elevated abeta42 in skeletal muscle of Alzheimer disease patients suggests peripheral alterations of AbetaPP metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Amyloid-beta peptides interact with plasma proteins and erythrocytes: implications for their quantitation in plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Novel Leu723Pro amyloid precursor protein mutation increases amyloid beta42(43) peptide levels and induces apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Plasma amyloid beta-peptide 1-42 and incipient Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Peptide compositions of the cerebrovascular and senile plaque core amyloid deposits of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the alpha 1-antichymotrypsin gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Early-onset Alzheimer disease caused by a new mutation (V717L) in the amyloid precursor protein gene

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Decreased beta-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Longitudinal study of cerebrospinal fluid amyloid proteins and apolipoprotein E in patients with probable Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Differences between vascular and plaque core amyloid in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease: implications for disease pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Cerebrospinal beta-amyloid ((1-42)) in early Alzheimer's disease: association with apolipoprotein E genotype and cognitive decline.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Amyloid and lipids in the pathology of Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Combination assay of CSF tau, A beta 1-40 and A beta 1-42(43) as a biochemical marker of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

CSF levels of tau, beta-amyloid(1-42) and GAP-43 in frontotemporal dementia, other types of dementia and normal aging

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

The genetic defect causing familial Alzheimer's disease maps on chromosome 21.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Soluble amyloid beta-protein is a marker of Alzheimer amyloid in brain but not in cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Biochemical evidence for the long-tail form (A beta 1-42/43) of amyloid beta protein as a seed molecule in cerebral deposits of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Amyloid beta protein in plasma from patients with sporadic Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Amyloid beta protein 42(43) in cerebrospinal fluid of patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Relationship between apoE genotype and CSF beta-amyloid (1-42) and tau in patients with probable and definite Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

The NINCDS-ADRDA Work Group criteria for the clinical diagnosis of probable Alzheimer's disease: a clinicopathologic study of 57 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Decreased Levels of Amyloid-beta 1-42 in Cerebrospinal Fluid of Creutzfeldt-Jakob Disease Patients

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Concentrations of amyloid beta protein in cerebrospinal fluid of patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Characterization of beta-amyloid peptide from human cerebrospinal fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

1 reference

https://api.crossref.org/works/10.1016%2FS0196-9781%2802%2900056-6

7 January 2021

10.1016/S0196-9781(02)00056-6

Identifiers

DOI

1 reference

4 August 2017

1 reference