(Q34752048)

4 August 2017

title

Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy (English)

1 reference

4 August 2017

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11

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4 August 2017

Tony Jourdan

1

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Resat Cinar

Resat Cinar

7

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Avi Rosenberg

Avi Z Rosenberg

3

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Brian James Earley

Brian James Earley

5

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Gergő Szanda

2

Gergő Szanda

1 reference

4 August 2017

Joseph Tam

4

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4 August 2017

Grzegorz Godlewski

6

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4 August 2017

Ziyi Liu

8

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4 August 2017

Jie Liu

9

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4 August 2017

Cynthia Ju

10

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4 August 2017

George Kunos

12

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4 August 2017

language of work or name

English

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publication date

24 November 2014

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Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

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4 August 2017

volume

111

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4 August 2017

issue

50

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4 August 2017

page(s)

E5420-8

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Estimating podocyte number and density using a single histologic section

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Nox as a target for diabetic complications

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Modulating the endocannabinoid system in human health and disease--successes and failures

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Uric acid best predicts metabolically unhealthy obesity with increased cardiovascular risk in youth and adults

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Angiotensin II reduces cardiac AdipoR1 expression through AT1 receptor/ROS/ERK1/2/c-Myc pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Renin inhibition in the treatment of diabetic kidney disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Cardinal role of the intrarenal renin-angiotensin system in the pathogenesis of diabetic nephropathy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Podocyte biology and pathogenesis of kidney disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Central and peripheral cannabinoid receptors as therapeutic targets in the control of food intake and body weight

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Angiotensin II induces tumor necrosis factor-α expression and release from cultured human podocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

The endocannabinoid system and plant-derived cannabinoids in diabetes and diabetic complications

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Hyperglycemia induces apoptosis via CB1 activation through the decrease of FAAH 1 in retinal pigment epithelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Role of angiotensin II in the development of nephropathy and podocytopathy of diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-gamma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

CB1 receptor inhibition leads to decreased vascular AT1 receptor expression, inhibition of oxidative stress and improved endothelial function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

CB1 antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

The future of endocannabinoid-oriented clinical research after CB1 antagonists.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Obesity, diabetes, and chronic kidney disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Insight on the pathogenesis of diabetic nephropathy from the study of podocyte and mesangial cell biology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Intrarenal oxidative stress and augmented angiotensinogen are precedent to renal injury in Zucker diabetic fatty rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Transcriptional regulation of the cannabinoid receptor type 1 gene in T cells by cannabinoids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

NADPH oxidases in the kidney

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Vascular NAD(P)H oxidases: specific features, expression, and regulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Podocyte injury promotes progressive nephropathy in zucker diabetic fatty rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Role of angiotensin II in diabetic nephropathy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Blockade of cannabinoid CB1 receptors improves renal function, metabolic profile, and increased survival of obese Zucker rats

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419901111

Ibipinabant attenuates β-cell loss in male Zucker diabetic fatty rats independently of its effects on body weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419901111

The effect of angiotensin II receptor blockade on an end-stage renal failure model of type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419901111

Analysis of the relationship of leptin, high-sensitivity C-reactive protein, adiponectin, insulin, and uric acid to metabolic syndrome in lean, overweight, and obese young females

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419901111

The high glucose-induced stimulation of B1R and B2R expression via CB(1)R activation is involved in rat podocyte apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419901111

Common polymorphism in the cannabinoid type 1 receptor gene (CNR1) is associated with microvascular complications in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419901111

Podocyte injury enhances filtration of liver-derived angiotensinogen and renal angiotensin II generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419901111

Increased inflammatory biomarkers in hypertensive type 2 diabetic patients: improvement after angiotensin II type 1 receptor blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419901111

Angiotensin II receptor blocker inhibits tumour necrosis factor-alpha-induced cell damage in human renal proximal tubular epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419901111

JD-5006 and JD-5037: peripherally restricted (PR) cannabinoid-1 receptor blockers related to SLV-319 (Ibipinabant) as metabolic disorder therapeutics devoid of CNS liabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419901111

Expression of cannabinoid receptors in human kidney

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273328

Magnitude of end-stage renal disease in IDDM: a 35 year follow-up study

26 October 2018

1 reference

12 December 2020

Renal effects of angiotensin II receptor blockade and angiotensin-converting enzyme inhibition in healthy subjects

1 reference

12 December 2020

Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance

1 reference

12 December 2020

Elevated atrial natriuretic peptides and early renal failure in type 2 diabetic Goto-Kakizaki rats

1 reference

12 December 2020

Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes

1 reference

12 December 2020

Blockade of cannabinoid receptor 1 improves insulin resistance, lipid metabolism, and diabetic nephropathy in db/db mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1419901111

1 reference

4 August 2017

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4 August 2017

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