(Q34752295)

4 August 2017

title

hERG 1b is critical for human cardiac repolarization (English)

1 reference

4 August 2017

David K Jones

1

0 references

author name string

Fang Liu

2

1 reference

4 August 2017

Ravi Vaidyanathan

3

1 reference

4 August 2017

L Lee Eckhardt

4

1 reference

4 August 2017

Matthew C Trudeau

5

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4 August 2017

Gail A Robertson

6

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4 August 2017

language of work or name

English

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publication date

1 December 2014

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4 August 2017

number of pages

5

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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4 August 2017

volume

111

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4 August 2017

issue

50

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4 August 2017

page(s)

18073-18077

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The enigmatic cytoplasmic regions of KCNH channels

4 August 2017

cites work

1 reference

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The eag domain regulates hERG channel inactivation gating via a direct interaction

7 July 2018

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Determinants of incomplete penetrance and variable expressivity in heritable cardiac arrhythmia syndromes

7 July 2018

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Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr).

7 July 2018

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Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel

7 July 2018

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hERG1a N-terminal eag domain-containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: a possible mechanism for long QT syndrome

7 July 2018

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7 July 2018

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hERG subunit composition determines differential drug sensitivity.

7 July 2018

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Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

7 July 2018

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7 July 2018

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7 July 2018

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Beat-by-beat QT interval variability, but not QT prolongation per se, predicts drug-induced torsades de pointes in the anaesthetised methoxamine-sensitized rabbit

7 July 2018

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Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics

7 July 2018

1 reference

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hERG1a/1b heteromeric currents exhibit amplified attenuation of inactivation in variant 1 short QT syndrome

7 July 2018

1 reference

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Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome

7 July 2018

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Endoplasmic reticulum retention and rescue by heteromeric assembly regulate human ERG 1a/1b surface channel composition

7 July 2018

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Cardiac IKr channels minimally comprise hERG 1a and 1b subunits

7 July 2018

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7 July 2018

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Differential distribution of cardiac ion channel expression as a basis for regional specialization in electrical function

7 July 2018

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Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain

7 July 2018

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Two isoforms of the mouse ether-a-go-go-related gene coassemble to form channels with properties similar to the rapidly activating component of the cardiac delayed rectifier K+ current

7 July 2018

1 reference

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Electrophysiological characterization of an alternatively processed ERG K+ channel in mouse and human hearts

7 July 2018

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High affinity open channel block by dofetilide of HERG expressed in a human cell line.

7 July 2018

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7 July 2018

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A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

7 July 2018

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HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

7 July 2018

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Excitation and Impulse Conduction in the Human Fetal Heart

7 July 2018

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7 July 2018

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Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs.

26 October 2018

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Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach.

26 October 2018

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International Conference on Harmonisation; guidance on S7B Nonclinical Evaluation of the Potential for Delayed Ventricular Repolarization (QT Interval Prolongation) by Human Pharmaceuticals; availability. Notice.

26 October 2018

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Prolongation of the QT interval and the sudden infant death syndrome.

26 October 2018

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Electrical activity of a single fibre of the human embryonic heart

26 October 2018

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12 December 2020

Basic electrophysiological parameters and frequency sensitivity of the ventricular myocardium of human embryos

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12 December 2020

In vivo mechanisms precipitating torsades de pointes in a canine model of drug-induced long-QT1 syndrome

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12 December 2020

Relation of increased short-term variability of QT interval to congenital long-QT syndrome

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12 December 2020

Usefulness of short-term variability of QT intervals as a predictor for electrical remodeling and proarrhythmia in patients with nonischemic heart failure

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12 December 2020

Translational potential of human embryonic and induced pluripotent stem cells for myocardial repair: insights from experimental models

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1414945111

1 reference

4 August 2017

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4 August 2017

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