(Q34753015)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

p53 prevents neurodegeneration by regulating synaptic genes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Bess Frost

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Shouyong Peng

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Yawei J Yang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Peter J Park

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Mel Feany

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

1 December 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

23 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

18055-18060

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

Connecting the dots between tau dysfunction and neurodegeneration

23 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Late-Onset Alzheimer's Disease Genes and the Potentially Implicated Pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Tau promotes neurodegeneration through global chromatin relaxation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

The genetics and neuropathology of Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

p73: a multifunctional protein in neurobiology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Replication of BIN1 association with Alzheimer's disease and evaluation of genetic interactions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Drosophila as a model for age-related impairment in locomotor and other behaviors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Genome-wide analysis of genetic loci associated with Alzheimer disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

p53-family proteins and their regulators: hubs and spokes in tumor suppression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Normalization and experimental design for ChIP-chip data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Cell cycle regulation in the postmitotic neuron: oxymoron or new biology?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Oxidative stress mediates tau-induced neurodegeneration in Drosophila

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

p53 isoforms can regulate p53 transcriptional activity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

MatInspector and beyond: promoter analysis based on transcription factor binding sites

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

The p53 homologue p73 accumulates in the nucleus and localizes to neurites and neurofibrillary tangles in Alzheimer disease brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Genetic modifiers of tauopathy in Drosophila.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Alzheimer's disease is a synaptic failure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Active genes are tri-methylated at K4 of histone H3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Targeted mutagenesis by homologous recombination in D. melanogaster

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Drosophila p53 binds a damage response element at the reaper locus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Drosophila p53 is a structural and functional homolog of the tumor suppressor p53.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Changes of p53 in the brains of patients with Alzheimer's disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273405

Cell cycle activation linked to neuronal cell death initiated by DNA damage

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

A neuroprotective role for the DNA damage checkpoint in tauopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

p63 Regulates adult neural precursor and newly born neuron survival to control hippocampal-dependent Behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

p73 or p53 directly regulates human p53 transcription to maintain cell cycle checkpoints.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

Contribution of asymmetric synapse loss to lateralizing clinical deficits in frontotemporal dementias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

Genetic association of PICALM polymorphisms with Alzheimer's disease in Han Chinese

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1419083111

21 January 2018

Identifiers

DOI

10.1073/PNAS.1419083111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25453105%20AND%20SRC:MED&resulttype=core&format=json