(Q34761828)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Novel delivery system enhances efficacy of antiretroviral therapy in animal model for HIV-1 encephalitis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

main subject

HIV

0 references

anti-retroviral agent

0 references

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

6

Howard E Gendelman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Timothy J Spitzenberger

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

David Heilman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Casey Diekmann

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Elena V Batrakova

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

William F Elmquist

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Yuri Persidsky

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

publication date

25 October 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

Journal of Cerebral Blood Flow & Metabolism

21 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

1033-1042

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

Blood-brain barrier: structural components and function under physiologic and pathologic conditions

21 December 2019

cites work

1 reference

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Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Hippocampal synaptic dysfunction in a murine model of human immunodeficiency virus type 1 encephalitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

In vitro and in vivo models for assessing drug efflux transporter activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

The multidrug transporter, P-glycoprotein, actively mediates cholesterol redistribution in the cell membrane

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Functional expression and localization of P-glycoprotein at the blood brain barrier

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Human immunodeficiency virus type 1 uses lipid raft-colocalized CD4 and chemokine receptors for productive entry into CD4(+) T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Impaired spatial cognition and synaptic potentiation in a murine model of human immunodeficiency virus type 1 encephalitis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Reservoirs of human immunodeficiency virus type 1: the main obstacles to viral eradication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Plasma membrane rafts play a critical role in HIV-1 assembly and release

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Functional expression of P-glycoprotein in rat brain microglia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

The late stage of human immunodeficiency virus type 1 assembly is an energy-dependent process

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

P-glycoprotein limits oral availability, brain, and fetal penetration of saquinavir even with high doses of ritonavir

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Pluronic P85 enhances the delivery of digoxin to the brain: in vitro and in vivo studies.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Mononuclear phagocytes mediate blood-brain barrier compromise and neuronal injury during HIV-1-associated dementia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Incidence and prevalence of neurological disorders associated with HIV since the introduction of highly active antiretroviral therapy (HAART).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Evaluation of antiretroviral drug efficacy for HIV-1 encephalitis in SCID mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

An analysis of HIV-1-associated inflammatory products in brain tissue of humans and SCID mice with HIV-1 encephalitis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Human immunodeficiency virus encephalitis in SCID mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Failure to detect nelfinavir in the cerebrospinal fluid of HIV-1--infected patients with and without AIDS dementia complex.

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

Optimal structure requirements for pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood–brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

Altered P-glycoprotein expression in AIDS patients with HIV encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

The efficacy of potent anti-retroviral drug combinations tested in a murine model of HIV-1 encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

Membrane fluidization by ether, other anesthetics, and certain agents abolishes P-glycoprotein ATPase activity and modulates efflux from multidrug-resistant cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

The membrane lipid environment modulates drug interactions with the P-glycoprotein multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

Effects of a P-glycoprotein inhibitor on brain and plasma concentrations of anti-human immunodeficiency virus drugs administered in combination in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

Differential effects of p-glycoprotein and multidrug resistance protein-1 on productive human immunodeficiency virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

Mechanism of pluronic effect on P-glycoprotein efflux system in blood-brain barrier: contributions of energy depletion and membrane fluidization.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070745

HIV-associated neurologic disease incidence changes:: Multicenter AIDS Cohort Study, 1990-1998

26 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.JCBFM.9600414

Fundamental relationships between the composition of pluronic block copolymers and their hypersensitization effect in MDR cancer cells

21 January 2018

1 reference

12 December 2020

Of mice and men: a model of HIV encephalitis

1 reference

12 December 2020

Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer

1 reference

12 December 2020

Effects of cholesterol and enantiomeric cholesterol on P-glycoprotein localization and function in low-density membrane domains

1 reference

12 December 2020

Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes

1 reference

12 December 2020

Neuropathology and general autopsy findings in AIDS during the last 15 years

1 reference

12 December 2020

Distribution kinetics of a micelle-forming block copolymer Pluronic P85

1 reference

12 December 2020

Micelles of poly(oxyethylene)-poly(oxypropylene) block copolymer (pluronic) as a tool for low-molecular compound delivery into a cell: phosphorylation of intracellular proteins with micelle incorporated [gamma-32P]ATP

1 reference

12 December 2020

Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapy

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.JCBFM.9600414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17063148%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PubMed publication ID

17063148

1 reference