(Q34768563)

4 August 2017

1 reference

title

HIV-1 regulatory proteins: targets for novel drug development (English)

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4 August 2017

1

Roger G Ptak

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4 August 2017

language of work or name

English

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publication date

1 August 2002

1 reference

Expert Opinion on Investigational Drugs

4 August 2017

published in

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4 August 2017

volume

11

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4 August 2017

issue

8

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4 August 2017

page(s)

1099-1115

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Transcription elongation factor P-TEFb mediates Tat activation of HIV-1 transcription at multiple stages

4 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Recruitment of cyclin T1/P-TEFb to an HIV type 1 long terminal repeat promoter proximal RNA target is both necessary and sufficient for full activation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Purification of a Tat-associated kinase reveals a TFIIH complex that modulates HIV-1 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Extensive interactions between HIV TAT and TAF(II)250.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Phosphorylation of the RAP74 subunit of TFIIF correlates with Tat-activated transcription of the HIV-1 long terminal repeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Regulation of carboxyl-terminal domain phosphatase by HIV-1 tat protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Cyclin T1 domains involved in complex formation with Tat and TAR RNA are critical for tat-activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Functional interaction between the HIV transactivator Tat and the transcriptional coactivator PC4 in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

HIV-1 Tat protein-mediated transactivation of the HIV-1 long terminal repeat promoter is potentiated by a novel nuclear Tat-interacting protein of 110 kDa, Tip110

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Human immunodeficiency virus type 1 Tat binding protein-1 is a transcriptional coactivator specific for TR

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

FBI-1 can stimulate HIV-1 Tat activity and is targeted to a novel subnuclear domain that includes the Tat-P-TEFb-containing nuclear speckles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Human GLI-2 is a tat activation response element-independent Tat cofactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

HIV-1 Tat protein interacts with mammalian capping enzyme and stimulates capping of TAR RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

HIV-1 tat transcriptional activity is regulated by acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Control of the histone-acetyltransferase activity of Tip60 by the HIV-1 transactivator protein, Tat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

The human immunodeficiency virus-1 Tat protein increases cell proliferation, alters sensitivity to zinc chelator-induced apoptosis, and changes Sp1 DNA binding in HeLa cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Association of HIV-1 Tat with the cellular protein, Puralpha, is mediated by RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Interaction of HIV-1 Tat with Puralpha in nuclei of human glial cells: characterization of RNA-mediated protein-protein binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Functional interaction between cyclin T1/cdk9 and Puralpha determines the level of TNFalpha promoter activation by Tat in glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Cell cycle regulation of human interleukin-8 gene expression by the human immunodeficiency virus type 1 Tat protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Tat is required for efficient HIV-1 reverse transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

The Tat protein of human immunodeficiency virus type 1 (HIV-1) can promote placement of tRNA primer onto viral RNA and suppress later DNA polymerization in HIV-1 reverse transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Role for human immunodeficiency virus type 1 Tat protein in suppression of viral reverse transcriptase activity during late stages of viral replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

HIV-1 Tat protein mimicry of chemokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Identification of specific molecular structures of human immunodeficiency virus type 1 Tat relevant for its biological effects on vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Angiogenic effects of extracellular human immunodeficiency virus type 1 Tat protein and its role in the pathogenesis of AIDS-associated Kaposi's sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Tat protein induces self-perpetuating permissivity for productive HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Nucleolar protein B23 stimulates nuclear import of the HIV-1 Rev protein and NLS-conjugated albumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

The post-transcriptional regulator Rev of HIV: implications for its interaction with the nucleolar protein B23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Structural model for the cooperative assembly of HIV-1 Rev multimers on the RRE as deduced from analysis of assembly-defective mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Site-specific phosphorylation of the human immunodeficiency virus type-1 Rev protein accelerates formation of an efficient RNA-binding conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Biochemical characterization of HIV-1 Rev as a potent activator of casein kinase II in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: implications for HIV-1 latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

In vitro interaction between human immunodeficiency virus type 1 Rev protein and splicing factor ASF/SF2-associated protein, p32

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

A human nucleoporin-like protein that specifically interacts with HIV Rev

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Identification of a novel cellular cofactor for the Rev/Rex class of retroviral regulatory proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

A new nucleoporin-like protein interacts with both HIV-1 Rev nuclear export signal and CRM-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Expression of exogenous Sam68, the 68-kilodalton SRC-associated protein in mitosis, is able to alleviate impaired Rev function in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

A role for KH domain proteins (Sam68-like mammalian proteins and quaking proteins) in the post-transcriptional regulation of HIV replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

A role for RNA helicase A in post-transcriptional regulation of HIV type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Sam68, RNA helicase A and Tap cooperate in the post-transcriptional regulation of human immunodeficiency virus and type D retroviral mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Inhibition of the HIV-1 rev-RRE complex formation by unfused aromatic cations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Aminoglycoside antibiotics, neamine and its derivatives as potent inhibitors for the RNA-protein interactions derived from HIV-1 activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Anti-HIV activity of a novel aminoglycoside-arginine conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

A new type of potent inhibitors of HIV-1 TAR RNA-Tat peptide binding by zinc(II)-macrocyclic tetraamine complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Docking studies reveal a selective binding of D-penicillamine to the transactivator protein of human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Aromatic polyamidines inhibiting the Tat-induced HIV-1 transcription recognize structured TAR-RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Inhibition of HIV-1 Tat-dependent trans activation by steric block chimeric 2'-O-methyl/LNA oligoribonucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Oligonucleotide analogue interference with the HIV-1 Tat protein-TAR RNA interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Enhanced inhibition of HIV-1 replication in macrophages by antisense oligonucleotides, ribozymes and acyclic nucleoside phosphonate analogs delivered in pH-sensitive liposomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

HIV Rev peptides conjugated with peptide nucleic acids and their efficient binding to RRE RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Construction of peptides with nucleobase amino acids: design and synthesis of the nucleobase-conjugated peptides derived from HIV-1 Rev and their binding properties to HIV-1 RRE RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

Pentosan polysulfate as an inhibitor of extracellular HIV-1 Tat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

HIV-1 Tat Inhibits IL-2 Gene Transcription Through Qualitative and Quantitative Alterations of the Cooperative Rel/AP1 Complex Bound to the CD28RE/AP1 Composite Element of the IL-2 Promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.11.8.1099

10.1517/13543784.11.8.1099

21 January 2018

Identifiers

DOI

1 reference

4 August 2017

1 reference