(Q34768887)

4 August 2017

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title

Tethering on the brink: the evolutionarily conserved Mre11-Rad50 complex (English)

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4 August 2017

John C Connelly

1

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4 August 2017

David R F Leach

series ordinal

2

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4 August 2017

publication date

1 August 2002

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4 August 2017

number of pages

9

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Trends in Biochemical Sciences

inferred from page(s)

published in

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4 August 2017

volume

27

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4 August 2017

issue

8

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4 August 2017

page(s)

410-418

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Recombination at double-strand breaks and DNA ends: conserved mechanisms from phage to humans.

4 August 2017

cites work

1 reference

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7 January 2021

Structural and functional similarities between the SbcCD proteins of Escherichia coli and the RAD50 and MRE11 (RAD32) recombination and repair proteins of yeast.

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7 January 2021

Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine

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https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

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7 January 2021

Cell-cycle regulation of mammalian DNA double-strand-break repair

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7 January 2021

A DNA damage response pathway controlled by Tel1 and the Mre11 complex

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7 January 2021

Complex formation and functional versatility of Mre11 of budding yeast in recombination

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7 January 2021

DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex

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7 January 2021

Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants

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7 January 2021

Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair

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7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

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7 January 2021

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

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7 January 2021

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

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7 January 2021

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

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7 January 2021

Recombination and recombination-dependent DNA replication in bacteriophage T4.

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7 January 2021

Escherichia coli sbcC mutants permit stable propagation of DNA replicons containing a long palindrome

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7 January 2021

Identification of sbcD mutations as cosuppressors of recBC that allow propagation of DNA palindromes in Escherichia coli K-12.

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7 January 2021

Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair

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7 January 2021

Genes involved in the determination of the rate of inversions at short inverted repeats

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7 January 2021

Role of genes 46 and 47 in bacteriophage T4 reproduction. II. Formation of gaps on parental DNA of polynucleotide ligase defective mutants

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7 January 2021

The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination.

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7 January 2021

Overexpression, purification, and characterization of the SbcCD protein from Escherichia coli.

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7 January 2021

The SbcCD nuclease of Escherichia coli is a structural maintenance of chromosomes (SMC) family protein that cleaves hairpin DNA

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https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

DNA cleavage and degradation by the SbcCD protein complex from Escherichia coli

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7 January 2021

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

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7 January 2021

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

1 reference

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7 January 2021

Human Rad50/Mre11 is a flexible complex that can tether DNA ends

1 reference

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7 January 2021

DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways

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7 January 2021

A mechanistic basis for Mre11-directed DNA joining at microhomologies

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7 January 2021

Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination

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7 January 2021

Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

1 reference

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7 January 2021

Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

Structure of the Rad50 x Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

The SbcCD protein of Escherichia coli is related to two putative nucleases in the UvrA superfamily of nucleotide-binding proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

The symmetrical structure of structural maintenance of chromosomes (SMC) and MukB proteins: long, antiparallel coiled coils, folded at a flexible hinge

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

Bimodal activation of SMC ATPase by intra- and inter-molecular interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

Molecular architecture of SMC proteins and the yeast cohesin complex

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

Multiple sequence alignment with hierarchical clustering

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

Envisioning the fourth dimension of the genetic code: the structural biology of macromolecular recognition and conformational switching in DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0968-0004%2802%2902144-8

7 January 2021

10.1016/S0968-0004(02)02144-8

Identifiers

DOI

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4 August 2017

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