(Q34769812)

4 August 2017

title

GM2/GD2 and GM3 gangliosides have no effect on cellular cholesterol pools or turnover in normal or NPC1 mice (English)

1 reference

4 August 2017

Hao Li

1

1 reference

4 August 2017

Stephen D Turley

2

1 reference

4 August 2017

Benny Liu

3

1 reference

4 August 2017

Joyce J Repa

4

1 reference

4 August 2017

John M Dietschy

5

1 reference

4 August 2017

publication date

30 April 2008

1 reference

Journal of Lipid Research

4 August 2017

published in

1 reference

4 August 2017

volume

49

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4 August 2017

issue

8

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4 August 2017

page(s)

1816-1828

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Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain

4 August 2017

cites work

1 reference

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Pregnane X receptor (PXR) activation: a mechanism for neuroprotection in a mouse model of Niemann-Pick C disease

7 July 2018

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The power of real-time PCR.

7 July 2018

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Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1/apolipoprotein A-I pathway: 1-phenyl-2-decanoylamino-3-morpholino-1-propanol is a novel cholesterol efflux accelerator

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Interruption of ganglioside synthesis produces central nervous system degeneration and altered axon-glial interactions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Quantitative real-time polymerase chain reaction measurement of regulators of G-protein signaling mRNA levels in mouse tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal

7 July 2018

1 reference

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Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport

7 July 2018

1 reference

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Enhanced insulin sensitivity in mice lacking ganglioside GM3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Combinatorial ganglioside biosynthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Control of cholesterol turnover in the mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Cessation of rapid late endosomal tubulovesicular trafficking in Niemann-Pick type C1 disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

How cells handle cholesterol.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Sterol-modulated glycolipid sorting occurs in niemann-pick C1 late endosomes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Intracellular cholesterol trafficking: role of the NPC1 protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Cholesterol accumulation in tissues of the Niemann-pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organ

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Lipid changes in Niemann-Pick disease type C brain: personal experience and review of the literature

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Sphingomyelin depletion in cultured cells blocks proteolysis of sterol regulatory element binding proteins at site 1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Cholesterol-induced interfacial area condensations of galactosylceramides and sphingomyelins with identical acyl chains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Depletion of plasma-membrane sphingomyelin rapidly alters the distribution of cholesterol between plasma membranes and intracellular cholesterol pools in cultured fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Tracking cell cholesterol with cholesterol oxidase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Receptor-mediated endocytosis: insights from the lipoprotein receptor system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Receptor-mediated and bulk-phase endocytosis cause macrophage and cholesterol accumulation in Niemann-Pick C disease

7 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800180-JLR200

Cholesterol accumulation in NPC1-deficient neurons is ganglioside dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800180-JLR200

Delineation of molecular changes in intrahepatic cholesterol metabolism resulting from diminished cholesterol absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800180-JLR200

Molecular, anatomical, and biochemical events associated with neurodegeneration in mice with Niemann-Pick type C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800180-JLR200

Cholesterol is sequestered in the brains of mice with Niemann-Pick type C disease but turnover is increased.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800180-JLR200

A novel cholesterol stain reveals early neuronal cholesterol accumulation in the Niemann-Pick type C1 mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800180-JLR200

Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800180-JLR200

Cholesterol substrate pools and steroid hormone levels are normal in the face of mutational inactivation of NPC1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800180-JLR200

Increased levels of GM2 ganglioside in fibroblasts from a patient with juvenile Niemann-Pick disease type C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800180-JLR200

Cholesterol accumulation and liver cell death in mice with Niemann-Pick type C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800180-JLR200

Cholesterol balance and metabolism in mice with loss of function of Niemann-Pick C protein.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

Membrane lipids of adult human brain: lipid composition of frontal and temporal lobe in subjects of age 20 to 100 years.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3072295

The role of sphingolipids in the process of signal transduction

26 October 2018

1 reference

12 December 2020

Rates of sterol synthesis and uptake in the major organs of the rat in vivo

1 reference

12 December 2020

Measurement of rates of cholesterol synthesis using tritiated water

1 reference

12 December 2020

Effects of sphingomyelin degradation on cell cholesterol oxidizability and steady-state distribution between the cell surface and the cell interior

1 reference

12 December 2020

Alleviation of neuronal ganglioside storage does not improve the clinical course of the Niemann-Pick C disease mouse

1 reference

12 December 2020

Centripetal cholesterol flow from the extrahepatic organs through the liver is normal in mice with mutated Niemann-Pick type C protein (NPC1)

1 reference

12 December 2020

Marked reduction in bile acid synthesis in cholesterol 7alpha-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia

1 reference

12 December 2020

Lysosomal unesterified cholesterol content correlates with liver cell death in murine Niemann-Pick type C disease

1 reference

12 December 2020

10.1194/JLR.M800180-JLR200

Identifiers

DOI

1 reference

4 August 2017

1 reference

4 August 2017

1 reference