(Q34770617)

4 August 2017

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title

Reactivating the expression of methylation silenced genes in human cancer (English)

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4 August 2017

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2

David A Jones

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4 August 2017

Adam R Karpf

1

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PubMed ID

12154410

4 August 2017

language of work or name

English

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publication date

1 August 2002

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4 August 2017

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4 August 2017

21

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4 August 2017

5496-5503

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4 August 2017

35

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205602

4 August 2017

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cites work

Unresponsiveness to interferon associated with STAT1 protein deficiency in a gastric adenocarcinoma cell line.

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DNA strand methylation and sister chromatid exchanges in mammalian cells in vitro

21 January 2018

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The promise of retinoids to fight against cancer.

21 January 2018

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Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin

21 January 2018

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DNA hypermethylation in tumorigenesis: epigenetics joins genetics

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Roles of cell division and gene transcription in the methylation of CpG islands.

21 January 2018

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DNA methylation as a target for drug design

21 January 2018

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Modified oligonucleotides as bona fide antagonists of proteins interacting with DNA. Hairpin antagonists of the human DNA methyltransferase

21 January 2018

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

21 January 2018

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Demethylase activity is directed by histone acetylation

21 January 2018

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DNA hypomethylation leads to elevated mutation rates

21 January 2018

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Sp1 binding is inhibited by (m)Cp(m)CpG methylation.

21 January 2018

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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

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The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation.

21 January 2018

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Role of estrogen receptor gene demethylation and DNA methyltransferase.DNA adduct formation in 5-aza-2'deoxycytidine-induced cytotoxicity in human breast cancer cells

21 January 2018

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DNA methyltransferase Dnmt1 associates with histone deacetylase activity

21 January 2018

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Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription

21 January 2018

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CpG methylation has differential effects on the binding of YY1 and ETS proteins to the bi-directional promoter of the Surf-1 and Surf-2 genes

21 January 2018

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The potential of melanoma antigen expression in cancer therapy

21 January 2018

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Identification and characterization of a family of mammalian methyl-CpG binding proteins

21 January 2018

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Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

21 January 2018

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Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase

21 January 2018

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Cancer epigenetics comes of age

21 January 2018

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Cellular differentiation, cytidine analogs and DNA methylation

21 January 2018

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

21 January 2018

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Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

21 January 2018

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Inhibition of DNA methyltransferase stimulates the expression of signal transducer and activator of transcription 1, 2, and 3 genes in colon tumor cells

21 January 2018

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Methylation profiles of genomic DNA of mouse developmental brain detected by restriction landmark genomic scanning (RLGS) method

21 January 2018

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Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

DNA methylation and genetic instability in colorectal cancer cells

21 January 2018

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5-Azacytidine and sodium butyrate induce expression of aromatase in fibroblasts from chickens carrying the henny feathering trait but not from wild-type chickens

21 January 2018

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Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

21 January 2018

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Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

Active repression of methylated genes by the chromosomal protein MBD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

Molecular portraits of human breast tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

DNA methylation, methyltransferases, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

DNA methylation, chromatin inheritance, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

Chronic myelogenous leukemia in nonlymphoid blastic phase: analysis of the results of first salvage therapy with three different treatment approaches for 162 patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

Quantitative monitoring of gene expression patterns with a complementary DNA microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

Trichostatin A causes selective loss of DNA methylation in Neurospora

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

Methylation of an ETS site in the intron enhancer of the keratin 18 gene participates in tissue-specific repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

Methyl CpG binding proteins: coupling chromatin architecture to gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

7 January 2021

Studies on the hypomethylation of c-myc, c-Ha-ras oncogenes and histopathological changes in human gastric carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

7 January 2021

Down-regulation of human DNA-(cytosine-5) methyltransferase induces cell cycle regulators p16(ink4A) and p21(WAF/Cip1) by distinct mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

7 January 2021

Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

7 January 2021

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

7 January 2021

Molecular alterations in the TP53 gene of peripheral blood cells of patients with chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

7 January 2021

A phase II study of 5-aza-2'deoxycytidine (decitabine) in hormone independent metastatic (D2) prostate cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205602

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205602

1 reference

PubMed ID

12154410

Dimensions Publication ID

4 August 2017

0 references

1 reference

PubMed ID

12154410