(Q34770630)

4 August 2017

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title

Modeling cancer in mice (English)

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4 August 2017

author name string

Laurie Jackson-Grusby

series ordinal

1

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4 August 2017

language of work or name

English

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publication date

1 August 2002

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4 August 2017

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4 August 2017

volume

21

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4 August 2017

issue

35

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4 August 2017

page(s)

5504-5514

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DNA hypermethylation in tumorigenesis: epigenetics joins genetics

4 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors

21 January 2018

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Improved properties of FLP recombinase evolved by cycling mutagenesis

21 January 2018

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Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse.

21 January 2018

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DNA hypomethylation leads to elevated mutation rates

21 January 2018

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Essential role for oncogenic Ras in tumour maintenance

21 January 2018

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Genomic analysis of metastasis reveals an essential role for RhoC

21 January 2018

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Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

The lac operator-repressor system is functional in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Lsh, a member of the SNF2 family, is required for genome-wide methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

New insights into host factor requirements for prokaryotic beta-recombinase-mediated reactions in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Reversible tumorigenesis by MYC in hematopoietic lineages

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Long-term, noninvasive imaging of regulated gene expression in living mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Dimeric ligands define a role for transcriptional activation domains in reinitiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Effects of an Rb mutation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Cancer epigenetics comes of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

The role of DNA methylation in cancer genetic and epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Targeted oncogene activation by site-specific recombination in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Conditional control of gene expression in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Ligand-regulated site-specific recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Production of gene-targeted sheep by nuclear transfer from cultured somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Recombinase-mediated gene activation and site-specific integration in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Chromosomal translocations in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Chromosome engineering in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Genome-wide location and function of DNA binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

The Kw recombinase, an integrase from Kluyveromyces waltii

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Generalized lacZ expression with the ROSA26 Cre reporter strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

21 January 2018

The new yeast genetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Visualizing the kinetics of tumor-cell clearance in living animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Chromosomal silencing and localization are mediated by different domains of Xist RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Cytosine methylation and the ecology of intragenomic parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

Hypomethylation of DNA from benign and malignant human colon neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

7 January 2021

Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

7 January 2021

Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

7 January 2021

Genome-wide analysis of DNA copy-number changes using cDNA microarrays

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

7 January 2021

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

7 January 2021

The cancer genome anatomy project: building an annotated gene index

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205603

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205603

1 reference

Dimensions Publication ID

4 August 2017

1029363793

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1 reference